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BACE2 beta-secretase 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100442149, updated on 26-Mar-2024

Summary

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Gene symbol
BACE2
Gene description
beta-secretase 2
Locus tag
CR201_G0029321
See related
Ensembl:ENSPPYG00000011433
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See BACE2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 22 NC_072007.2 (51524746..51632566)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 21 NC_072006.1 (45702736..45809501)

Chromosome 22 - NC_072007.2Genomic Context describing neighboring genes Neighboring gene DS cell adhesion molecule Neighboring gene uncharacterized LOC129052326 Neighboring gene small nucleolar RNA SNORA51 Neighboring gene uncharacterized LOC129052328 Neighboring gene placenta-specific protein 4-like Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene MX dynamin like GTPase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 2
Names
beta-site APP-cleaving enzyme 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072007.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    51524746..51632566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009233980.4 → XP_009232255.3  beta-secretase 2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Miscellaneous