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IL12B interleukin 12B [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100435254, updated on 26-Mar-2024

Summary

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Gene symbol
IL12B
Gene description
interleukin 12B
Locus tag
CR201_G0004656
See related
Ensembl:ENSPPYG00000016000
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 4 NC_071989.2 (168066246..168082445, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 5 NC_071990.1 (167288015..167304504, complement)

Chromosome 4 - NC_071989.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA68 Neighboring gene ubiquitin like domain containing CTD phosphatase 1 Neighboring gene U4atac minor spliceosomal RNA Neighboring gene uncharacterized LOC103890763 Neighboring gene uncharacterized LOC134761451

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-12 subunit beta
Names
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071989.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    168066246..168082445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054556166.2 → XP_054412141.1  interleukin-12 subunit beta isoform X2

  2. XM_002816140.5 → XP_002816186.1  interleukin-12 subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A2J8X6W7, A0A663DH67, H2PH86
    Related
    ENSPPYP00000017906.1
    Conserved Domains (3) summary
    smart00408
    Location:42 → 90
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:235 → 325
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam10420
    Location:126 → 216
    IL12p40_C; Cytokine interleukin-12p40 C-terminus
Nucleotide Protein
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Gene LinkOut

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