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SHARPIN SHANK associated RH domain interactor [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100392136, updated on 8-Mar-2024

Summary

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Gene symbol
SHARPIN
Gene description
SHANK associated RH domain interactor
See related
Ensembl:ENSCJAG00000021452
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
human mouse all
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Genomic context

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See SHARPIN in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 16 NC_071457.1 (51845180..51850087)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 16 NC_048398.1 (51987252..51992301)

Chromosome 16 - NC_071457.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 97 Neighboring gene MAF1 homolog, negative regulator of RNA polymerase III Neighboring gene cytochrome c-1 Neighboring gene glycosylphosphatidylinositol anchor attachment 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences. Maudhoo MD, et al. Gigascience, 2014. PMID 25243066, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein linear polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of LUBAC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sharpin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071457.1 Reference mCalJa1.2.pat.X

    Range
    51845180..51850087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035276481.2 → XP_035132372.1  sharpin isoform X1

    UniProtKB/TrEMBL
    U3BMK3
    Conserved Domains (4) summary
    smart00547
    Location:370 → 391
    ZnF_RBZ; Zinc finger domain
    sd00029
    Location:370 → 389
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cd01799
    Location:236 → 320
    Ubl_HOIL1; ubiquitin-like (Ubl) domain found in heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1) and similar proteins
    pfam16764
    Location:30 → 128
    Sharpin_PH; Sharpin PH domain

  2. XM_035276482.2 → XP_035132373.1  sharpin isoform X2

    UniProtKB/TrEMBL
    U3BMK3
    Conserved Domains (4) summary
    smart00547
    Location:368 → 389
    ZnF_RBZ; Zinc finger domain
    sd00029
    Location:368 → 387
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cd01799
    Location:236 → 320
    Ubl_HOIL1; ubiquitin-like (Ubl) domain found in heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1) and similar proteins
    pfam16764
    Location:30 → 128
    Sharpin_PH; Sharpin PH domain

  3. XM_002759147.6 → XP_002759193.3  sharpin isoform X3

    See identical proteins and their annotated locations for XP_002759193.3

    UniProtKB/TrEMBL
    F7DAG5, F7DAH8, U3BMK3
    Related
    ENSCJAP00000039928.2
    Conserved Domains (4) summary
    smart00547
    Location:353 → 374
    ZnF_RBZ; Zinc finger domain
    sd00029
    Location:353 → 372
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam16764
    Location:30 → 127
    Sharpin_PH; Sharpin PH domain
    cl00155
    Location:241 → 301
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
Heading Accession and Version

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