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DNA2 DNA replication helicase/nuclease 2 [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100391749, updated on 8-Mar-2024

Summary

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Gene symbol
DNA2
Gene description
DNA replication helicase/nuclease 2
See related
Ensembl:ENSCJAG00000019040
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 12 NC_071453.1 (58508741..58561843)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 12 NC_048394.1 (59316722..59369834)

Chromosome 12 - NC_071453.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 25 member 16 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L36a-like Neighboring gene U6 spliceosomal RNA Neighboring gene RUN and FYVE domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences. Maudhoo MD, et al. Gigascience, 2014. PMID 25243066, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-flap endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in replication fork reversal IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication ATP-dependent helicase/nuclease DNA2
Names
DNA replication helicase 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071453.1 Reference mCalJa1.2.pat.X

    Range
    58508741..58561843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009009829.4 → XP_009008077.1  DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1

    UniProtKB/TrEMBL
    F7IQ53
    Related
    ENSCJAP00000035413.2
    Conserved Domains (5) summary
    pfam08696
    Location:71 → 282
    Dna2; DNA replication factor Dna2
    pfam13086
    Location:625 → 796
    AAA_11; AAA domain
    pfam13087
    Location:805 → 1018
    AAA_12; AAA domain
    cl00641
    Location:259 → 397
    Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
    cl21455
    Location:625 → 829
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_009009831.4 → XP_009008079.1  DNA replication ATP-dependent helicase/nuclease DNA2 isoform X2

    UniProtKB/TrEMBL
    F7IQ53
    Conserved Domains (5) summary
    pfam08696
    Location:71 → 282
    Dna2; DNA replication factor Dna2
    pfam13086
    Location:548 → 719
    AAA_11; AAA domain
    pfam13087
    Location:728 → 941
    AAA_12; AAA domain
    cl00641
    Location:259 → 397
    Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
    cl21455
    Location:548 → 752
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_009009828.4 → XP_009008076.1  DNA replication ATP-dependent helicase/nuclease DNA2 isoform X3

    UniProtKB/TrEMBL
    F7IQ53
    Conserved Domains (5) summary
    TIGR00376
    Location:471 → 1033
    TIGR00376; DNA helicase, putative
    pfam08696
    Location:71 → 282
    Dna2; DNA replication factor Dna2
    pfam13087
    Location:805 → 1018
    AAA_12; AAA domain
    cl00641
    Location:259 → 397
    Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
    cl21455
    Location:625 → 829
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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