DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: DYRK1A
Gene description: dual specificity tyrosine phosphorylation regulated kinase 1A
See related: Ensembl:ENSOCUG00000005814
Gene type: protein coding
RefSeq status: MODEL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: DYRK; MNBH; RP86
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	Unplaced Scaffold	NW_026259175.1 (1845470..1990444, complement)

NW_026259175.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NW_026259175 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine/tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-threonine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity tyrosine-phosphorylation-regulated kinase 1A

Names: Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Protein kinase minibrain homolog; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

NW_026259175.1 Reference UM_NZW_1.0 Primary Assembly

Range

1845470..1990444 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008274878.3 → XP_008273100.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

See identical proteins and their annotated locations for XP_008273100.1

UniProtKB/TrEMBL

A0A5F9CH10, G1SPQ6

Conserved Domains (2) summary

smart00220
Location:159 → 479

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_017350781.2 → XP_017206270.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A5F9CH10, G1SPQ6

Conserved Domains (2) summary

smart00220
Location:159 → 479

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_051833628.1 → XP_051689588.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

A0A5F9CH10
XM_051833624.1 → XP_051689584.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A5F9CH10, G1SPQ6
XM_051833625.1 → XP_051689585.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

A0A5F9CH10
XM_051833623.1 → XP_051689583.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A5F9CH10, G1SPQ6
XM_051833627.1 → XP_051689587.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

A0A5F9CH10