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ME3 malic enzyme 3 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100342604, updated on 8-Mar-2024

Summary

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Gene symbol
ME3
Gene description
malic enzyme 3
See related
Ensembl:ENSOCUG00000012005
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 1 NC_067374.1 (143937931..144133895)

Chromosome 1 - NC_067374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127483673 Neighboring gene serine protease 23 Neighboring gene coiled-coil domain containing 81 Neighboring gene protein tyrosine phosphatase type IVA 1 Neighboring gene 60S ribosomal protein L39-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067374.1 Chromosome 1 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyruvate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADP-dependent malic enzyme, mitochondrial
Names
malic enzyme 3, NADP(+)-dependent, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067374.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    143937931..144133895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008263027.3 → XP_008261249.1  NADP-dependent malic enzyme, mitochondrial

    See identical proteins and their annotated locations for XP_008261249.1

    UniProtKB/TrEMBL
    G1T2F0
    Conserved Domains (3) summary
    cd05312
    Location:305 → 582
    NAD_bind_1_malic_enz; NAD(P) binding domain of malic enzyme (ME), subgroup 1
    PLN03129
    Location:4 → 588
    PLN03129; NADP-dependent malic enzyme; Provisional
    pfam00390
    Location:114 → 295
    malic; Malic enzyme, N-terminal domain

  2. XM_002708650.4 → XP_002708696.1  NADP-dependent malic enzyme, mitochondrial

    See identical proteins and their annotated locations for XP_002708696.1

    UniProtKB/TrEMBL
    G1T2F0
    Related
    ENSOCUP00000035588.1
    Conserved Domains (3) summary
    cd05312
    Location:305 → 582
    NAD_bind_1_malic_enz; NAD(P) binding domain of malic enzyme (ME), subgroup 1
    PLN03129
    Location:4 → 588
    PLN03129; NADP-dependent malic enzyme; Provisional
    pfam00390
    Location:114 → 295
    malic; Malic enzyme, N-terminal domain
Nucleotide Protein
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