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tti2 TELO2 interacting protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 100334230, updated on 11-Apr-2024

Summary

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Official Symbol
tti2provided by ZNC
Official Full Name
TELO2 interacting protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-25
See related
Ensembl:ENSDARG00000073773 AllianceGenome:ZFIN:ZDB-GENE-110411-25
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch73-316k5.2
Summary
Predicted to be part of ASTRA complex. Predicted to be active in centrosome; cytosol; and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TTI2 (TELO2 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See tti2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (45381322..45395244)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (45373444..45387365)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene poly(A) binding protein, cytoplasmic 1-like Neighboring gene charged multivesicular body protein 4Bb Neighboring gene MAK16 homolog (S. cerevisiae) Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b Neighboring gene uncharacterized LOC792551

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of TTT Hsp90 cochaperone complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TTT Hsp90 cochaperone complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TELO2-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    45381322..45395244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002663205.5 → XP_002663251.1  TELO2-interacting protein 2

    UniProtKB/TrEMBL
    A0A8M1RR58, E7F592
    Related
    ENSDARP00000100891.3, ENSDART00000110364.4
    Conserved Domains (1) summary
    pfam10521
    Location:148 → 372
    DUF2454; Protein of unknown function (DUF2454)
Nucleotide Protein Strain
Heading Accession and Version

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