nsun6 NOP2/Sun RNA methyltransferase 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nsun6provided by ZNC
Official Full Name: NOP2/Sun RNA methyltransferase 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-080808-8
See related: Ensembl:ENSDARG00000103478 AllianceGenome:ZFIN:ZDB-GENE-080808-8
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable RNA binding activity and methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to act upstream of or within methylation. Orthologous to human NSUN6 (NOP2/Sun RNA methyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (71776924..71812909)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (71585139..71621117)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA methylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within RNA methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative methyltransferase NSUN6

Names: NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

71776924..71812909

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017357152.2 → XP_017212641.1 putative methyltransferase NSUN6 isoform X2

UniProtKB/TrEMBL

A0A8M6Z0B3

Conserved Domains (3) summary

smart00359
Location:111 → 199

PUA; Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase

COG0144
Location:184 → 458

RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

cl17173
Location:225 → 455

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_017357149.2 → XP_017212638.1 putative methyltransferase NSUN6 isoform X1

UniProtKB/TrEMBL

A0A0R4IAT4, A0A8M2BGC6

Related

ENSDARP00000131024.1, ENSDART00000158782.2

Conserved Domains (3) summary

smart00359
Location:112 → 200

PUA; Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase

COG0144
Location:185 → 459

RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

cl17173
Location:226 → 456

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_017357151.2 → XP_017212640.1 putative methyltransferase NSUN6 isoform X1

UniProtKB/TrEMBL

A0A0R4IAT4, A0A8M2BGC6

Conserved Domains (3) summary

smart00359
Location:112 → 200

PUA; Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase

COG0144
Location:185 → 459

RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

cl17173
Location:226 → 456

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_005169055.4 → XP_005169112.1 putative methyltransferase NSUN6 isoform X1

See identical proteins and their annotated locations for XP_005169112.1

UniProtKB/TrEMBL

A0A0R4IAT4, A0A8M2BGC6

Conserved Domains (3) summary

smart00359
Location:112 → 200

PUA; Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase

COG0144
Location:185 → 459

RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

cl17173
Location:226 → 456

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_017357150.2 → XP_017212639.1 putative methyltransferase NSUN6 isoform X1

UniProtKB/TrEMBL

A0A0R4IAT4, A0A8M2BGC6

Related

ENSDARP00000137583.1, ENSDART00000161344.3

Conserved Domains (3) summary

smart00359
Location:112 → 200

PUA; Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase

COG0144
Location:185 → 459

RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

cl17173
Location:226 → 456

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...