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Kcnj2 potassium inwardly rectifying channel subfamily J member 2 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100135566, updated on 8-Mar-2024

Summary

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Gene symbol
Kcnj2
Gene description
potassium inwardly rectifying channel subfamily J member 2
See related
Ensembl:ENSCPOG00000004956
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Also known as
IRK1; IRK-1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947495.1 (4886968..4897348, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176416.1 (72605637..72614801)

NW_026947495.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478379 Neighboring gene ferritin light chain-like Neighboring gene uncharacterized LOC106025457 Neighboring gene potassium inwardly rectifying channel subfamily J member 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional expression of a vertebrate inwardly rectifying K+ channel in yeast. Tang W, et al. Mol Biol Cell, 1995 Sep. PMID 8534918, Free PMC Article
  2. Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes. Liu GX, et al. J Physiol, 2001 Apr 1. PMID 11283229, Free PMC Article
  3. Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. Rae JL, et al. Exp Eye Res, 1998 Mar. PMID 9533862

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inward rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inward rectifier potassium channel 2
Names
cardiac inward rectifier potassium channel
inward rectifier K(+) channel Kir2.1
inward rectifier potassium channel Kir2.1
inwardly-rectifying potassium channel Kir2.1
potassium channel, inwardly rectifying subfamily J member 2
potassium voltage-gated channel subfamily J member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172975.1 → NP_001166446.1  inward rectifier potassium channel 2

    See identical proteins and their annotated locations for NP_001166446.1

    Status: PROVISIONAL

    Source sequence(s)
    AF183914
    UniProtKB/Swiss-Prot
    P52185
    UniProtKB/TrEMBL
    A0A2C9F1F5, Q549A2
    Conserved Domains (3) summary
    pfam01007
    Location:48 → 186
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:1 → 47
    IRK_N; Inward rectifier potassium channel N-terminal
    pfam17655
    Location:193 → 366
    IRK_C; Inward rectifier potassium channel C-terminal domain

RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947495.1 Reference mCavPor4.1

    Range
    4886968..4897348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013142291.3 → XP_012997745.1  inward rectifier potassium channel 2 isoform X1

    See identical proteins and their annotated locations for XP_012997745.1

    UniProtKB/Swiss-Prot
    P52185
    UniProtKB/TrEMBL
    A0A2C9F1F5, Q549A2
    Related
    ENSCPOP00000031029.1
    Conserved Domains (3) summary
    pfam01007
    Location:48 → 186
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:1 → 47
    IRK_N; Inward rectifier potassium channel N-terminal
    pfam17655
    Location:193 → 366
    IRK_C; Inward rectifier potassium channel C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P52185.1 GenPept UniProtKB/Swiss-Prot:P52185

Gene LinkOut

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