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DIO1 iodothyronine deiodinase 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100101570, updated on 8-Mar-2024

Summary

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Gene symbol
DIO1
Gene description
iodothyronine deiodinase 1
See related
Ensembl:ENSOCUG00000008826
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See DIO1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 13 NC_067386.1 (112983112..112997125, complement)

Chromosome 13 - NC_067386.1Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 25 Neighboring gene uncharacterized LOC127493903 Neighboring gene U6 spliceosomal RNA Neighboring gene Yip1 domain family member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067386.1 Chromosome 13 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness. Debaveye Y, et al. Thyroid, 2008 May. PMID 18466079

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thyroxine 5'-deiodinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
type I iodothyronine deiodinase
Names
5DI
DIOI
deiodinase, iodothyronine type I
type 1 DI
type-I 5'-deiodinase
NP_001093428.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099958.1 → NP_001093428.1  type I iodothyronine deiodinase

    See identical proteins and their annotated locations for NP_001093428.1

    Status: VALIDATED

    Source sequence(s)
    EF428025
    UniProtKB/Swiss-Prot
    A4GT88
    UniProtKB/TrEMBL
    G1SVZ1
    Related
    ENSOCUP00000007619.3, ENSOCUT00000008823.3
    Conserved Domains (1) summary
    cl00388
    Location:8 → 248
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067386.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    112983112..112997125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4GT88.2 GenPept UniProtKB/Swiss-Prot:A4GT88

Gene LinkOut

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