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PTPRK protein tyrosine phosphatase receptor type K [ Equus caballus (horse) ]

Gene ID: 100073063, updated on 17-Aug-2024

Summary

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Official Symbol
PTPRKprovided by VGNC
Official Full Name
protein tyrosine phosphatase receptor type Kprovided by VGNC
Primary source
VGNC:VGNC:22034
See related
Ensembl:ENSECAG00000005833
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See PTPRK in Genome Data Viewer
Location:
chromosome: 10
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 10 NC_009153.3 (75874122..76377182, complement)

Chromosome 10 - NC_009153.3Genomic Context describing neighboring genes Neighboring gene chromosome 10 C6orf58 homolog Neighboring gene thymocyte selection associated Neighboring gene nucleoside diphosphate kinase B pseudogene Neighboring gene laminin subunit alpha 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009153.3 Chromosome 10 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase kappa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009153.3 Reference EquCab3.0 Primary Assembly

    Range
    75874122..76377182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023651051.1 → XP_023506819.1  receptor-type tyrosine-protein phosphatase kappa isoform X3

    UniProtKB/TrEMBL
    A0A3Q2HWN4
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:929 → 1156
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain

  2. XM_023651049.1 → XP_023506817.1  receptor-type tyrosine-protein phosphatase kappa isoform X1

    UniProtKB/TrEMBL
    A0A3Q2HWN4
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00409
    Location:201 → 287
    IG; Immunoglobulin
    cd00047
    Location:929 → 1162
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain

  3. XM_023651050.1 → XP_023506818.1  receptor-type tyrosine-protein phosphatase kappa isoform X2

    UniProtKB/TrEMBL
    A0A3Q2HWN4
    Related
    ENSECAP00000005913.2, ENSECAT00000007969.4
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00409
    Location:201 → 287
    IG; Immunoglobulin
    cd00047
    Location:928 → 1161
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain

  4. XM_023651052.1 → XP_023506820.1  receptor-type tyrosine-protein phosphatase kappa isoform X4

    UniProtKB/TrEMBL
    A0A3Q2IAE1
    Related
    ENSECAP00000042821.3, ENSECAT00000035676.3
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00409
    Location:201 → 287
    IG; Immunoglobulin
    cd00047
    Location:913 → 1146
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain

  5. XM_023651054.1 → XP_023506822.1  receptor-type tyrosine-protein phosphatase kappa isoform X6

    UniProtKB/TrEMBL
    A0A3Q2GYB7
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:912 → 1139
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain

  6. XM_023651053.1 → XP_023506821.1  receptor-type tyrosine-protein phosphatase kappa isoform X5

    UniProtKB/TrEMBL
    A0A3Q2GYB7
    Related
    ENSECAP00000025973.3, ENSECAT00000034511.3
    Conserved Domains (4) summary
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:913 → 1140
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00041
    Location:487 → 582
    fn3; Fibronectin type III domain
Nucleotide Protein
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