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LOC100072916 arachidonate 12-lipoxygenase, 12S-type [ Equus caballus (horse) ]

Gene ID: 100072916, updated on 18-Sep-2024

Summary

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Gene symbol
LOC100072916
Gene description
arachidonate 12-lipoxygenase, 12S-type
See related
Ensembl:ENSECAG00000022015
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
ALOX12
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Genomic context

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Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (50370279..50382072)

Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene arachidonate 12-lipoxygenase, 12S-type Neighboring gene uncharacterized LOC111775726 Neighboring gene uncharacterized LOC111775725 Neighboring gene uncharacterized LOC111775727 Neighboring gene chromosome 11 C17orf49 homolog Neighboring gene ribonuclease K

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009154.3 Chromosome 11 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in arachidonate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hepoxilin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoxygenase pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12S-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009154.3 Reference EquCab3.0 Primary Assembly

    Range
    50370279..50382072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014737319.2 → XP_014592805.2  arachidonate 12-lipoxygenase, 12S-type

    UniProtKB/TrEMBL
    A0A9L0TNZ0, F6X3M3
    Related
    ENSECAP00000019594.2, ENSECAT00000023641.3
    Conserved Domains (2) summary
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    cl27717
    Location:217 → 654
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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