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UCP1 uncoupling protein 1 [ Equus caballus (horse) ]

Gene ID: 100063105, updated on 17-Aug-2024

Summary

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Official Symbol
UCP1provided by VGNC
Official Full Name
uncoupling protein 1provided by VGNC
Primary source
VGNC:VGNC:24766
See related
Ensembl:ENSECAG00000026962
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 2 NC_009145.3 (91148926..91160923)

Chromosome 2 - NC_009145.3Genomic Context describing neighboring genes Neighboring gene ring finger protein 150 Neighboring gene TBC1 domain family member 9 Neighboring gene uncharacterized LOC111770373 Neighboring gene ELMO domain containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009145.3 Chromosome 2 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interplay Among the Daily Rhythm of the Thyroid Hormones, Uncoupling Protein 1 and the Clock Gene Per2 in Horses. Giannetto C, et al. J Equine Vet Sci, 2023 Jul. PMID 37088111
  2. Serum levels of mitochondrial uncoupling protein 1, leptin, and lipids during late pregnancy and the early postpartum period in mares. Arfuso F, et al. Theriogenology, 2016 Sep 15. PMID 27165993

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Interplay Among the Daily Rhythm of the Thyroid Hormones, Uncoupling Protein 1 and the Clock Gene Per2 in Horses.
    Title: Interplay Among the Daily Rhythm of the Thyroid Hormones, Uncoupling Protein 1 and the Clock Gene Per2 in Horses.
  2. Significant negative correlations were found between UCP1 and total lipids, triglycerides, VLDLs, Total-Chol, and LDL values. Positive correlations were found between leptin and total lipids, triglycerides, VLDLs, Total-Chol, and LDLs.
    Title: Serum levels of mitochondrial uncoupling protein 1, leptin, and lipids during late pregnancy and the early postpartum period in mares.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidative phosphorylation uncoupler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adaptive thermogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cold IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: mitochondrial brown fat uncoupling protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009145.3 Reference EquCab3.0 Primary Assembly

    Range
    91148926..91160923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001915531.2 → XP_001915566.2  LOW QUALITY PROTEIN: mitochondrial brown fat uncoupling protein 1

    UniProtKB/TrEMBL
    F6PTQ7
    Related
    ENSECAP00000022921.2, ENSECAT00000028856.3
    Conserved Domains (1) summary
    pfam00153
    Location:107 → 203
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
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