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DOCK10 dedicator of cytokinesis 10 [ Equus caballus (horse) ]

Gene ID: 100061558, updated on 8-Mar-2024

Summary

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Official Symbol
DOCK10provided by VGNC
Official Full Name
dedicator of cytokinesis 10provided by VGNC
Primary source
VGNC:VGNC:17263
See related
Ensembl:ENSECAG00000000357
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See DOCK10 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
60
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (13181873..13360461, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 6 NC_009149.2 (13401655..13610870, complement)

Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene cullin 3 Neighboring gene putative coiled-coil domain-containing protein 195 Neighboring gene neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 Neighboring gene uncharacterized LOC111773788

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dendritic spine morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dedicator of cytokinesis protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009149.3 Reference EquCab3.0 Primary Assembly

    Range
    13181873..13360461 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001493461.6 → XP_001493511.3  dedicator of cytokinesis protein 10 isoform X8

    UniProtKB/TrEMBL
    A0A9L0S524, F6XD01
    Related
    ENSECAP00000002093.4, ENSECAT00000002924.4
    Conserved Domains (4) summary
    cd08697
    Location:665 → 854
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1685 → 2130
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cd13267
    Location:176 → 296
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:59 → 147
    DUF3398; Domain of unknown function (DUF3398)

  2. XM_023642438.1 → XP_023498206.1  dedicator of cytokinesis protein 10 isoform X5

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1460 → 1907
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  3. XM_023642440.1 → XP_023498208.1  dedicator of cytokinesis protein 10 isoform X7

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cl06123
    Location:1469 → 1881
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  4. XM_023642439.1 → XP_023498207.1  dedicator of cytokinesis protein 10 isoform X6

    UniProtKB/TrEMBL
    A0A9L0S524
    Related
    ENSECAP00000002049.4, ENSECAT00000002863.4
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cl06123
    Location:1469 → 1883
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  5. XM_023642437.1 → XP_023498205.1  dedicator of cytokinesis protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1469 → 1914
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  6. XM_023642435.1 → XP_023498203.1  dedicator of cytokinesis protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1469 → 1914
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  7. XM_023642436.1 → XP_023498204.1  dedicator of cytokinesis protein 10 isoform X3

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1469 → 1916
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain

  8. XM_023642434.1 → XP_023498202.1  dedicator of cytokinesis protein 10 isoform X1

    UniProtKB/TrEMBL
    A0A9L0S524
    Conserved Domains (3) summary
    cd08697
    Location:449 → 638
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11699
    Location:1469 → 1916
    DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
    cl17171
    Location:1 → 80
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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