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SESN3 sestrin 3 [ Equus caballus (horse) ]

Gene ID: 100061072, updated on 17-Aug-2024

Summary

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Official Symbol
SESN3provided by VGNC
Official Full Name
sestrin 3provided by VGNC
Primary source
VGNC:VGNC:22871
See related
Ensembl:ENSECAG00000017743
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See SESN3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 7 NC_009150.3 (6770732..6838923, complement)

Chromosome 7 - NC_009150.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111774206 Neighboring gene endonuclease domain containing 1 Neighboring gene uncharacterized LOC111774207 Neighboring gene uncharacterized LOC111774209 Neighboring gene uncharacterized LOC111774208 Neighboring gene microRNA mir-7143 Neighboring gene uncharacterized LOC106783371

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009150.3 Chromosome 7 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin-3
Names
Sestrin-3-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009150.3 Reference EquCab3.0 Primary Assembly

    Range
    6770732..6838923 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001916022.5 → XP_001916057.1  sestrin-3 isoform X1

    See identical proteins and their annotated locations for XP_001916057.1

    UniProtKB/TrEMBL
    A0A9L0TR43
    Related
    ENSECAP00000089626.1, ENSECAT00000095786.1
    Conserved Domains (1) summary
    pfam04636
    Location:39 → 490
    PA26; PA26 p53-induced protein (sestrin)

  2. XM_023644693.1 → XP_023500461.1  sestrin-3 isoform X2

    UniProtKB/TrEMBL
    F6S6U7
    Related
    ENSECAP00000053383.1, ENSECAT00000077781.2
    Conserved Domains (1) summary
    pfam04636
    Location:1 → 412
    PA26; PA26 p53-induced protein (sestrin)
Nucleotide Protein
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