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HMCN1 hemicentin 1 [ Equus caballus (horse) ]

Gene ID: 100052277, updated on 8-Mar-2024

Summary

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Official Symbol
HMCN1provided by VGNC
Official Full Name
hemicentin 1provided by VGNC
Primary source
VGNC:VGNC:18801
See related
Ensembl:ENSECAG00000007173
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See HMCN1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
109
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (19618847..20058399)
102 previous assembly EquCab2.0 (GCF_000002305.2) 5 NC_009148.2 (22378165..22816071)

Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102149797 Neighboring gene uncharacterized LOC111773470 Neighboring gene 1-acyl-sn-glycerol-3-phosphate acyltransferase beta-like Neighboring gene microRNA mir-8969 Neighboring gene proteoglycan 4 Neighboring gene translocated promoter region, nuclear basket protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell-cell adhesion mediator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dendrite self-avoidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hemicentin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009148.3 Reference EquCab3.0 Primary Assembly

    Range
    19618847..20058399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023640716.1 → XP_023496484.1  hemicentin-1 isoform X6

    UniProtKB/TrEMBL
    A0A9L0SCV6
    Conserved Domains (9) summary
    smart00209
    Location:4589 → 4641
    TSP1; Thrombospondin type 1 repeats
    smart00409
    Location:896 → 977
    IG; Immunoglobulin
    smart00410
    Location:1086 → 1167
    IG_like; Immunoglobulin like
    cd00198
    Location:42 → 198
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07679
    Location:1171 → 1258
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2383 → 2461
    Ig_3; Immunoglobulin domain
    cd00096
    Location:3169 → 3238
    Ig; Immunoglobulin domain
    cl11960
    Location:2222 → 2277
    Ig; Immunoglobulin domain
    cl28434
    Location:520 → 608
    I-set; Immunoglobulin I-set domain

  2. XM_023640714.1 → XP_023496482.1  hemicentin-1 isoform X4

    UniProtKB/TrEMBL
    A0A9L0SCV6
    Conserved Domains (12) summary
    smart00179
    Location:5432 → 5471
    EGF_CA; Calcium-binding EGF-like domain
    smart00209
    Location:4589 → 4641
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1086 → 1167
    IG_like; Immunoglobulin like
    smart00682
    Location:4868 → 5092
    G2F; G2 nidogen domain and fibulin
    cd00054
    Location:5230 → 5263
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00198
    Location:42 → 198
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07679
    Location:1171 → 1258
    I-set; Immunoglobulin I-set domain
    pfam07645
    Location:5272 → 5313
    EGF_CA; Calcium-binding EGF domain
    pfam13927
    Location:2383 → 2461
    Ig_3; Immunoglobulin domain
    cd00096
    Location:3169 → 3238
    Ig; Immunoglobulin domain
    cl11960
    Location:2222 → 2277
    Ig; Immunoglobulin domain
    cl28434
    Location:3354 → 3430
    I-set; Immunoglobulin I-set domain

  3. XM_023640713.1 → XP_023496481.1  hemicentin-1 isoform X3

    UniProtKB/TrEMBL
    A0A9L0SCV6, A0A9L0SJG4
    Related
    ENSECAP00000074334.1, ENSECAT00000107608.1
    Conserved Domains (12) summary
    smart00179
    Location:5315 → 5354
    EGF_CA; Calcium-binding EGF-like domain
    smart00209
    Location:4589 → 4641
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1086 → 1167
    IG_like; Immunoglobulin like
    smart00682
    Location:4868 → 5092
    G2F; G2 nidogen domain and fibulin
    cd00054
    Location:5230 → 5263
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00198
    Location:42 → 198
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07679
    Location:1171 → 1258
    I-set; Immunoglobulin I-set domain
    pfam07645
    Location:5272 → 5313
    EGF_CA; Calcium-binding EGF domain
    pfam13927
    Location:2383 → 2461
    Ig_3; Immunoglobulin domain
    cd00096
    Location:3169 → 3238
    Ig; Immunoglobulin domain
    cl11960
    Location:2222 → 2277
    Ig; Immunoglobulin domain
    cl28434
    Location:3354 → 3430
    I-set; Immunoglobulin I-set domain

  4. XM_001491510.5 → XP_001491560.2  hemicentin-1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0SCV6, F6TQY1
    Related
    ENSECAP00000006481.3, ENSECAT00000008627.4
    Conserved Domains (12) summary
    smart00179
    Location:5432 → 5471
    EGF_CA; Calcium-binding EGF-like domain
    smart00209
    Location:4589 → 4641
    TSP1; Thrombospondin type 1 repeats
    smart00409
    Location:1086 → 1167
    IG; Immunoglobulin
    smart00682
    Location:4868 → 5092
    G2F; G2 nidogen domain and fibulin
    cd00054
    Location:5230 → 5263
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00198
    Location:42 → 198
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07679
    Location:1171 → 1258
    I-set; Immunoglobulin I-set domain
    pfam07645
    Location:5272 → 5313
    EGF_CA; Calcium-binding EGF domain
    pfam13927
    Location:2383 → 2461
    Ig_3; Immunoglobulin domain
    cd00096
    Location:3169 → 3238
    Ig; Immunoglobulin domain
    cl11960
    Location:2222 → 2277
    Ig; Immunoglobulin domain
    cl28434
    Location:3354 → 3430
    I-set; Immunoglobulin I-set domain

  5. XM_023640712.1 → XP_023496480.1  hemicentin-1 isoform X2

    UniProtKB/TrEMBL
    A0A9L0SCV6
    Conserved Domains (12) summary
    smart00179
    Location:5390 → 5429
    EGF_CA; Calcium-binding EGF-like domain
    smart00209
    Location:4547 → 4599
    TSP1; Thrombospondin type 1 repeats
    smart00409
    Location:854 → 935
    IG; Immunoglobulin
    smart00410
    Location:1044 → 1125
    IG_like; Immunoglobulin like
    smart00682
    Location:4826 → 5050
    G2F; G2 nidogen domain and fibulin
    cd00054
    Location:5188 → 5221
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07679
    Location:1129 → 1216
    I-set; Immunoglobulin I-set domain
    pfam07645
    Location:5230 → 5271
    EGF_CA; Calcium-binding EGF domain
    pfam13927
    Location:2341 → 2419
    Ig_3; Immunoglobulin domain
    cd00096
    Location:3127 → 3196
    Ig; Immunoglobulin domain
    cl11960
    Location:2180 → 2235
    Ig; Immunoglobulin domain
    cl28434
    Location:3312 → 3388
    I-set; Immunoglobulin I-set domain

  6. XM_023640715.1 → XP_023496483.1  hemicentin-1 isoform X5

    UniProtKB/TrEMBL
    A0A9L0SCV6
    Conserved Domains (12) summary
    smart00179
    Location:4787 → 4826
    EGF_CA; Calcium-binding EGF-like domain
    smart00209
    Location:3944 → 3996
    TSP1; Thrombospondin type 1 repeats
    smart00409
    Location:251 → 332
    IG; Immunoglobulin
    smart00410
    Location:441 → 522
    IG_like; Immunoglobulin like
    smart00682
    Location:4223 → 4447
    G2F; G2 nidogen domain and fibulin
    cd00054
    Location:4585 → 4618
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07679
    Location:526 → 613
    I-set; Immunoglobulin I-set domain
    pfam07645
    Location:4627 → 4668
    EGF_CA; Calcium-binding EGF domain
    pfam13927
    Location:1738 → 1816
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2524 → 2593
    Ig; Immunoglobulin domain
    cl11960
    Location:1577 → 1632
    Ig; Immunoglobulin domain
    cl28434
    Location:2709 → 2785
    I-set; Immunoglobulin I-set domain

RNA

  1. XR_002807924.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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