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bcar3 BCAR3, NSP family adaptor protein [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100036719, updated on 8-Mar-2024

Summary

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Official Symbol
bcar3provided by Xenbase
Official Full Name
BCAR3, NSP family adaptor proteinprovided by Xenbase
Primary source
Xenbase:XB-GENE-6076062
See related
Ensembl:ENSXETG00000008226
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
nsp2; and-34; sh2d3b
Orthologs
human mouse all
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Genomic context

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See bcar3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (103941757..104016101)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (93766767..93847038)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene putative ferric-chelate reductase 1 Neighboring gene transfer RNA arginine (anticodon UCU) Neighboring gene uncharacterized LOC116410431 Neighboring gene formin binding protein 1 like Neighboring gene uncharacterized LOC105947290 Neighboring gene uncharacterized XB1000829 Neighboring gene down-regulator of transcription 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
breast cancer anti-estrogen resistance protein 3
Names
breast cancer anti-estrogen resistance 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097265.1 → NP_001090734.1  breast cancer anti-estrogen resistance protein 3

    See identical proteins and their annotated locations for NP_001090734.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129006
    UniProtKB/TrEMBL
    A1L1D5, F7CNV7
    Related
    ENSXETP00000018036.5, ENSXETT00000018036.5
    Conserved Domains (2) summary
    cd10337
    Location:147 → 282
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:536 → 808
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    103941757..104016101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012960374.3 → XP_012815828.2  breast cancer anti-estrogen resistance protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6I8SUE4, A0A8J0SH89
    Conserved Domains (2) summary
    cd10337
    Location:59 → 194
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:448 → 720
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_018092863.2 → XP_017948352.2  breast cancer anti-estrogen resistance protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8J0T340
    Conserved Domains (1) summary
    cl02485
    Location:228 → 500
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein Strain
Heading Accession and Version

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