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MTA1 metastasis associated 1 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100014351, updated on 8-May-2024

Summary

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Gene symbol
MTA1
Gene description
metastasis associated 1
See related
EnsemblRapid:ENSMODG00000014663
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See MTA1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 1 NC_077227.1 (303406082..303598526)
103 previous assembly MonDom5 (GCF_000002295.2) 1 NC_008801.1 (296835649..297026661)

Chromosome 1 - NC_077227.1Genomic Context describing neighboring genes Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC103099361 Neighboring gene mitogen-activated protein kinase 1-like Neighboring gene uncharacterized LOC103101570 Neighboring gene cysteine rich protein 2 Neighboring gene cysteine rich protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metastasis-associated protein MTA1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077227.1 Reference mMonDom1.pri

    Range
    303406082..303598526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016425614.2 → XP_016281100.1  metastasis-associated protein MTA1 isoform X5

    Related
    ENSMODP00000018323.5, ENSMODT00000018656.5

  2. XM_056821296.1 → XP_056677274.1  metastasis-associated protein MTA1 isoform X6

  3. XM_007473327.3 → XP_007473389.1  metastasis-associated protein MTA1 isoform X1

    UniProtKB/TrEMBL
    F7EPH6
    Related
    ENSMODP00000074973.1, ENSMODT00000144875.1
    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  4. XM_007473331.3 → XP_007473393.1  metastasis-associated protein MTA1 isoform X3

    Related
    ENSMODP00000062558.1, ENSMODT00000109374.1
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:371 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  5. XM_007473329.3 → XP_007473391.1  metastasis-associated protein MTA1 isoform X2

    UniProtKB/TrEMBL
    A0A5F8GVT0
    Related
    ENSMODP00000070319.1, ENSMODT00000131837.1
    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  6. XM_007473332.3 → XP_007473394.1  metastasis-associated protein MTA1 isoform X4

    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:371 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain
Nucleotide Protein
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