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KANK2 KN motif and ankyrin repeat domains 2 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100011126, updated on 8-May-2024

Summary

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Gene symbol
KANK2
Gene description
KN motif and ankyrin repeat domains 2
See related
EnsemblRapid:ENSMODG00000006347
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See KANK2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 3 NC_077229.1 (96905495..96933823)
103 previous assembly MonDom5 (GCF_000002295.2) 3 NC_008803.1 (429869683..429898013)

Chromosome 3 - NC_077229.1Genomic Context describing neighboring genes Neighboring gene tetraspanin 16 Neighboring gene dedicator of cytokinesis 6 Neighboring gene angiopoietin like 8 Neighboring gene SPC24 component of NDC80 kinetochore complex Neighboring gene low density lipoprotein receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of intracellular estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of vitamin D receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
KN motif and ankyrin repeat domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077229.1 Reference mMonDom1.pri

    Range
    96905495..96933823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007488515.2 → XP_007488577.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_007488577.1

    Related
    ENSMODP00000007877.5, ENSMODT00000008036.5
    Conserved Domains (6) summary
    cd00204
    Location:760 → 891
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12075
    Location:31 → 69
    KN_motif; KN motif
    pfam12796
    Location:770 → 868
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:731 → 786
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:857 → 912
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:765 → 797
    ANK; ANK repeat [structural motif]

  2. XM_007488518.2 → XP_007488580.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    F6ZS59
    Conserved Domains (6) summary
    cd00204
    Location:759 → 890
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12075
    Location:31 → 69
    KN_motif; KN motif
    pfam12796
    Location:769 → 867
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:730 → 785
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:856 → 911
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:764 → 796
    ANK; ANK repeat [structural motif]

  3. XM_007488519.3 → XP_007488581.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X3

    Conserved Domains (4) summary
    cd00204
    Location:759 → 833
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12075
    Location:31 → 69
    KN_motif; KN motif
    pfam13637
    Location:766 → 825
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:765 → 797
    ANK; ANK repeat [structural motif]

  4. XM_056822736.1 → XP_056678714.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X4

  5. XM_007488516.3 → XP_007488578.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_007488578.1

    Conserved Domains (6) summary
    cd00204
    Location:760 → 891
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12075
    Location:31 → 69
    KN_motif; KN motif
    pfam12796
    Location:770 → 868
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:731 → 786
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:857 → 912
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:765 → 797
    ANK; ANK repeat [structural motif]

  6. XM_056822733.1 → XP_056678711.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

  7. XM_007488517.2 → XP_007488579.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_007488579.1

    Conserved Domains (6) summary
    cd00204
    Location:760 → 891
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12075
    Location:31 → 69
    KN_motif; KN motif
    pfam12796
    Location:770 → 868
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:731 → 786
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:857 → 912
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:765 → 797
    ANK; ANK repeat [structural motif]

  8. XM_056822735.1 → XP_056678713.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    F6ZS59

  9. XM_056822734.1 → XP_056678712.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    F6ZS59
Nucleotide Protein
Heading Accession and Version

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