ClinVar Genomic variation as it relates to human health
NM_002524.5(NRAS):c.222A>G (p.Thr74=)
Germline
Classification
(3)
Benign/Likely benign
criteria provided, multiple submitters, no conflicts
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
NRAS | - | - |
GRCh38 GRCh37 |
285 | 307 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
Likely benign (1) |
|
Mar 1, 2021 | RCV002428208.2 | |
Benign (1) |
|
Nov 27, 2023 | RCV003098737.2 | |
NRAS-related disorder
|
Likely benign (1) |
|
Jul 9, 2021 | RCV003896188.1 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated May 19, 2024