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Literature

PubMed

PubMed® comprises more than 36 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Featured Bookshelf titles

LiverTox

Clinical and Research Information on Drug-Induced Liver Injury

Drug Therapy for Early Rheumatoid Arthritis

A Systematic Review Update

Donahue KE, Gartlehner G, Schulman ER, et al.

Browse the Bookshelf

Literature databases

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Data

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein sequence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information

News

Research news

NIH News Releases JAN. 31, 2024

NIH study shows higher mortality rates for patients on respiratory support in rural intermediate care units

Findings highlight the importance of providing ICU-level care to rural patients with respiratory failure

The Scientist JAN. 29, 2024

Zero Gravity, Zero Gain: The Genetics Behind Muscle Loss in Space

Simulated microgravity in mice reveals a constellation of genes that may influence muscle weakening during spaceflight.

NPR News JAN. 28, 2024

Coronavirus FAQ: How long does my post-COVID protection last? When is it booster time?

Max Barnhart

How long does immunity last after an infection? Are rapid tests always accurate? How often is a booster in order? In this installment of our FAQ series, we look into questions about "COVID time."

More news

Recent blog posts

NIH Director's Blog FEB. 1, 2024

Findings in Tuberculosis Immunity Point Toward New Approaches to Treatment and Prevention

Tuberculosis, caused by the bacteria Mycobacterium tuberculosis (Mtb), took 1.3 million lives in 2022, making it the second leading infectious killer around the world after COVID-19. Current TB treatments require months of daily medicine and certain cases of TB are becoming increasingly difficult to treat because of drug resistance. While TB case counts had been steadily decreasing before the COVID-19 pandemic, in the last couple of years there’s been an uptick. Although a TB vaccine exists and offers some protection to young children, the vaccine, known as BCG, has not effectively prevented TB in adults. Developing more protective and longer lasting TB vaccines remains an urgent priority for NIH. As part of this effort, NIH Immune Mechanisms of Protection Against Mycobacterium tuberculosis Centers (IMPAc-TB) are working to learn more about how we can harness our immune systems to mount the best protection against Mtb. And I’m happy to share some encouraging results now reported in the journal PLoS Pathogens, which show progress in understanding TB immunity and suggest additional strategies to fight this deadly bacterial infection in the future.

NCBI Insights JAN. 31, 2024

Enhancements to ClinVar Website Now Live

As previously announced, we updated the ClinVar website as part of our effort to better support the display of submitted somatic variation data.  What changed?  Updated ClinVar search results Germline / Somatic origin filter Somatic Classification and Review Status summary Updated Variant (VCV)  record page Includes both Germline and Somatic data for the same variant … Continue reading Enhancements to ClinVar Website Now Live

NCBI Insights JAN. 30, 2024

HomoloGene Now Redirects to NCBI Datasets Gene

A new way to view and download related genes  As previously announced, HomoloGene now automatically redirects to the NCBI Datasets Gene page giving you easy access to up-to-date sequence and homology data. The NCBI Datasets Gene Table provides a link to NCBI Orthologs with expanded gene and protein information and links to tools. NCBI Orthologs … Continue reading HomoloGene Now Redirects to NCBI Datasets Gene