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NCBI Insights MAY 13, 2021

Prokaryotic representative genomes update–over 900 new species!

We are happy to announce an updated bacterial and archaeal representative genome collection! We have selected 13,835 among 214,000 prokaryotic RefSeq assemblies to represent their respective species. The collection has increased by 6% since December 2020. About 950 species are represented for the first time, 476 species are represented by a better assembly, and 170 …

NIH Director's Blog MAY 13, 2021

Finding Better Ways to Image the Retina

Every day, all around the world, eye care professionals are busy performing dilated eye exams. By looking through a patient's widened pupil, they can view the retina—the postage stamp-sized tissue lining the back of the inner eye—and look for irregularities that may signal the development of vision loss.

NCBI Insights MAY 12, 2021

Assemble and annotate your prokaryotic genomes with RAPT

Do you need an easy way to analyze a bacterium you just isolated? The Read assembly and Annotation Pipeline Tool (RAPT) is a pilot service for the assembly and gene annotation of public or private Illumina genomic reads sequenced from bacterial or archaeal isolates. We’ll be giving a webinar on webRAPT on May 19, but …

Research news

NPR News YESTERDAY

Confused By CDC's Latest Mask Guidance? Here's What We've Learned

The Centers for Disease Control and Prevention shifted its stance this week on the need to wear masks if you're vaccinated. What's that mean for kids? For travel? For work? Experts weigh in.

The Scientist YESTERDAY

COVID-19’s Origins Need Further Investigation, Say Scientists

A letter signed by 18 researchers argues that hypotheses about zoonotic spillover or accidental lab release both "remain viable" in the absence of additional evidence.

More news COVID-19 news

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NCBI Virus

The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences

LitCovid

A curated literature hub for the latest scientific information on COVID-19

BLAST

Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis

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The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

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MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

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Experimentally-determined biomolecular structures

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Genome sequence assemblies, large-scale functional genomics data, and source biological samples

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Genome assembly information

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Biological projects providing data to NCBI

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Descriptions of biological source materials

Genome

Genome sequencing projects by organism

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DNA and RNA sequences

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High-throughput sequence reads

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Taxonomic classification and nomenclature

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein seqeuence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

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Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

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Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

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Online mendelian inheritance in man

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Repository of chemical information, molecular pathways, and tools for bioactivity screening

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Bioactivity screening studies

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Chemical information with structures, information and links

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Molecular pathways with links to genes, proteins and chemicals

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Deposited substance and chemical information