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Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
A tool to find regions of similarity between biological sequences
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
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Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
Repository of chemical information, molecular pathways, and tools for bioactivity screening
NIH-funded study explains how intravenous immune globulin helps children with rare COVID condition.
Scientists are learning how this pollutant damages plants and trees, setting off a cascade of effects that harms everything from soil microbes to wildlife.
Recent blog posts
Guest post by Valerie Schneider, PhD, staff scientist at the National Library of Medicine’s National Center for Biotechnology Information, National Institutes of Health. In a post from earlier this year, A Journey to Spur Innovation and Discovery, I shared news of an exciting NIH-supported NLM initiative, now known as the NIH Comparative Genomics Resource (CGR). … Continue reading "Using Comparative Genomics to Advance Scientific Discoveries"
In response to your requests for compact and faster-to-deliver data, NIH’s Sequence Read Archive (SRA) now offers a new data format – SRA Lite (Figure 1). SRA Lite supports reliable and faster data transfer, downloads, and analysis using current tools. SRA Lite replaces the submitted base quality score (BQS) with a simplified read quality score, … Continue reading The Sequence Read Archive slims down your data with SRA Lite
Any of the available COVID-19 vaccines offer remarkable personal protection against the coronavirus SARS-CoV-2. So, it also stands to reason that folks who are vaccinated will reduce the risk of spreading the virus to family members within their households. That protection is particularly important when not all family members can be immunized—as when there are children under age 12 or adults with immunosuppression in the home. But just how much can vaccines help to protect families from COVID-19 when only some, not all, in the household have immunity?