Name: rs153734
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs153734

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr3:64092333 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.277211 (73375/264690, TOPMED)
C=0.215346 (54933/255092, ALFA)
C=0.284098 (39797/140082, GnomAD) (+ 20 more)
C=0.43531 (12301/28258, 14KJPN)
C=0.43228 (7245/16760, 8.3KJPN)
C=0.3220 (2062/6404, 1000G_30x)
C=0.3213 (1609/5008, 1000G)
C=0.2527 (1132/4480, Estonian)
C=0.2187 (843/3854, ALSPAC)
C=0.2203 (817/3708, TWINSUK)
C=0.4358 (1277/2930, KOREAN)
C=0.2893 (603/2084, HGDP_Stanford)
C=0.3774 (711/1884, HapMap)
C=0.4416 (809/1832, Korea1K)
C=0.213 (213/998, GoNL)
C=0.385 (303/786, PRJEB37584)
C=0.228 (137/600, NorthernSweden)
C=0.208 (103/496, SGDP_PRJ)
C=0.171 (37/216, Qatari)
C=0.425 (91/214, Vietnamese)
C=0.29 (24/84, Ancient Sardinia)
C=0.23 (12/52, Siberian)
C=0.28 (11/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: PRICKLE2-AS1 : Intron Variant
PRICKLE2 : 3 Prime UTR Variant
Publications: 3 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	255186	C=0.215325	T=0.784675
European	Sub	217718	C=0.207305	T=0.792695
African	Sub	10408	C=0.44264	T=0.55736
African Others	Sub	360	C=0.442	T=0.558
African American	Sub	10048	C=0.44268	T=0.55732
Asian	Sub	796	C=0.438	T=0.562
East Asian	Sub	618	C=0.439	T=0.561
Other Asian	Sub	178	C=0.438	T=0.562
Latin American 1	Sub	986	C=0.231	T=0.769
Latin American 2	Sub	9056	C=0.1184	T=0.8816
South Asian	Sub	5056	C=0.2225	T=0.7775
Other	Sub	11166	C=0.21789	T=0.78211

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	C=0.277211	T=0.722789
Allele Frequency Aggregator	Total	Global	255092	C=0.215346	T=0.784654
Allele Frequency Aggregator	European	Sub	217642	C=0.207318	T=0.792682
Allele Frequency Aggregator	Other	Sub	11148	C=0.21807	T=0.78193
Allele Frequency Aggregator	African	Sub	10408	C=0.44264	T=0.55736
Allele Frequency Aggregator	Latin American 2	Sub	9056	C=0.1184	T=0.8816
Allele Frequency Aggregator	South Asian	Sub	5056	C=0.2225	T=0.7775
Allele Frequency Aggregator	Latin American 1	Sub	986	C=0.231	T=0.769
Allele Frequency Aggregator	Asian	Sub	796	C=0.438	T=0.562
gnomAD - Genomes	Global	Study-wide	140082	C=0.284098	T=0.715902
gnomAD - Genomes	European	Sub	75886	C=0.22245	T=0.77755
gnomAD - Genomes	African	Sub	41956	C=0.43450	T=0.56550
gnomAD - Genomes	American	Sub	13658	C=0.15800	T=0.84200
gnomAD - Genomes	Ashkenazi Jewish	Sub	3322	C=0.1740	T=0.8260
gnomAD - Genomes	East Asian	Sub	3114	C=0.4329	T=0.5671
gnomAD - Genomes	Other	Sub	2146	C=0.2805	T=0.7195
14KJPN	JAPANESE	Study-wide	28258	C=0.43531	T=0.56469
8.3KJPN	JAPANESE	Study-wide	16760	C=0.43228	T=0.56772
1000Genomes_30x	Global	Study-wide	6404	C=0.3220	T=0.6780
1000Genomes_30x	African	Sub	1786	C=0.4866	T=0.5134
1000Genomes_30x	Europe	Sub	1266	C=0.2291	T=0.7709
1000Genomes_30x	South Asian	Sub	1202	C=0.2113	T=0.7887
1000Genomes_30x	East Asian	Sub	1170	C=0.4171	T=0.5829
1000Genomes_30x	American	Sub	980	C=0.164	T=0.836
1000Genomes	Global	Study-wide	5008	C=0.3213	T=0.6787
1000Genomes	African	Sub	1322	C=0.4803	T=0.5197
1000Genomes	East Asian	Sub	1008	C=0.4117	T=0.5883
1000Genomes	Europe	Sub	1006	C=0.2286	T=0.7714
1000Genomes	South Asian	Sub	978	C=0.218	T=0.782
1000Genomes	American	Sub	694	C=0.167	T=0.833
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.2527	T=0.7473
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.2187	T=0.7813
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.2203	T=0.7797
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.4358	G=0.0000, T=0.5642
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	C=0.2893	T=0.7107
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	C=0.421	T=0.579
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	C=0.261	T=0.739
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	C=0.234	T=0.766
HGDP-CEPH-db Supplement 1	Europe	Sub	320	C=0.209	T=0.791
HGDP-CEPH-db Supplement 1	Africa	Sub	242	C=0.574	T=0.426
HGDP-CEPH-db Supplement 1	America	Sub	216	C=0.005	T=0.995
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	C=0.11	T=0.89
HapMap	Global	Study-wide	1884	C=0.3774	T=0.6226
HapMap	American	Sub	766	C=0.283	T=0.717
HapMap	African	Sub	690	C=0.541	T=0.459
HapMap	Asian	Sub	254	C=0.382	T=0.618
HapMap	Europe	Sub	174	C=0.138	T=0.862
Korean Genome Project	KOREAN	Study-wide	1832	C=0.4416	T=0.5584
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.213	T=0.787
CNV burdens in cranial meningiomas	Global	Study-wide	786	C=0.385	T=0.615
CNV burdens in cranial meningiomas	CRM	Sub	786	C=0.385	T=0.615
Northern Sweden	ACPOP	Study-wide	600	C=0.228	T=0.772
SGDP_PRJ	Global	Study-wide	496	C=0.208	T=0.792
Qatari	Global	Study-wide	216	C=0.171	T=0.829
A Vietnamese Genetic Variation Database	Global	Study-wide	214	C=0.425	T=0.575
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	84	C=0.29	T=0.71
Siberian	Global	Study-wide	52	C=0.23	T=0.77
The Danish reference pan genome	Danish	Study-wide	40	C=0.28	T=0.72

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 3	NC_000003.12:g.64092333C>G
GRCh38.p14 chr 3	NC_000003.12:g.64092333C>T
GRCh37.p13 chr 3	NC_000003.11:g.64078009C>G
GRCh37.p13 chr 3	NC_000003.11:g.64078009C>T
PRICKLE2 RefSeqGene	NG_031930.1:g.138123G>C
PRICKLE2 RefSeqGene	NG_031930.1:g.138123G>A

Gene: PRICKLE2, prickle planar cell polarity protein 2 (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PRICKLE2 transcript variant 1	NM_198859.4:c.*6718=	N/A	3 Prime UTR Variant
PRICKLE2 transcript variant 2	NM_001370528.1:c.*6718=	N/A	3 Prime UTR Variant

Gene: PRICKLE2-AS1, PRICKLE2 antisense RNA 1 (plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PRICKLE2-AS1 transcript	NR_045697.1:n.	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	G	T
GRCh38.p14 chr 3	NC_000003.12:g.64092333=	NC_000003.12:g.64092333C>G	NC_000003.12:g.64092333C>T
GRCh37.p13 chr 3	NC_000003.11:g.64078009=	NC_000003.11:g.64078009C>G	NC_000003.11:g.64078009C>T
PRICKLE2 RefSeqGene	NG_031930.1:g.138123=	NG_031930.1:g.138123G>C	NG_031930.1:g.138123G>A
PRICKLE2 transcript variant 1	NM_198859.4:c.*6718=	NM_198859.4:c.*6718G>C	NM_198859.4:c.*6718G>A
PRICKLE2 transcript variant 2	NM_001370528.1:c.*6718=	NM_001370528.1:c.*6718G>C	NM_001370528.1:c.*6718G>A

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

151 SubSNP, 23 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	KWOK	ss321510	Jul 12, 2000 (79)
2	KWOK	ss331366	Jul 12, 2000 (79)
3	KWOK	ss1141300	Oct 04, 2000 (86)
4	KWOK	ss1141920	Oct 04, 2000 (86)
5	KWOK	ss1787629	Oct 18, 2000 (87)
6	KWOK	ss1787800	Oct 18, 2000 (87)
7	TSC-CSHL	ss2154042	Oct 23, 2000 (88)
8	YUSUKE	ss3253545	Sep 28, 2001 (100)
9	SC_JCM	ss3606747	Sep 28, 2001 (100)
10	BCM_SSAHASNP	ss10099059	Jul 11, 2003 (116)
11	SSAHASNP	ss22018571	Apr 05, 2004 (121)
12	PERLEGEN	ss23910531	Sep 20, 2004 (123)
13	ABI	ss44419208	Mar 13, 2006 (126)
14	AFFY	ss66147290	Nov 30, 2006 (127)
15	ILLUMINA	ss66830505	Nov 30, 2006 (127)
16	ILLUMINA	ss67127834	Nov 30, 2006 (127)
17	ILLUMINA	ss67467093	Nov 30, 2006 (127)
18	ILLUMINA	ss70441223	May 17, 2007 (127)
19	ILLUMINA	ss70629848	May 23, 2008 (130)
20	ILLUMINA	ss71179738	May 17, 2007 (127)
21	ILLUMINA	ss75883690	Dec 07, 2007 (129)
22	AFFY	ss76171866	Dec 08, 2007 (129)
23	KRIBB_YJKIM	ss83369259	Dec 14, 2007 (130)
24	HGSV	ss83579866	Dec 14, 2007 (130)
25	HGSV	ss84047385	Dec 14, 2007 (130)
26	BCMHGSC_JDW	ss92116166	Mar 24, 2008 (129)
27	HUMANGENOME_JCVI	ss99098273	Feb 03, 2009 (130)
28	BGI	ss103944443	Dec 01, 2009 (131)
29	1000GENOMES	ss110265635	Jan 24, 2009 (130)
30	1000GENOMES	ss111833060	Jan 25, 2009 (130)
31	ILLUMINA-UK	ss117110476	Feb 14, 2009 (130)
32	ILLUMINA	ss121741030	Dec 01, 2009 (131)
33	ENSEMBL	ss135280123	Dec 01, 2009 (131)
34	ENSEMBL	ss138904595	Dec 01, 2009 (131)
35	ILLUMINA	ss153499707	Dec 01, 2009 (131)
36	GMI	ss155570394	Dec 01, 2009 (131)
37	ILLUMINA	ss159282020	Dec 01, 2009 (131)
38	ILLUMINA	ss160368793	Dec 01, 2009 (131)
39	COMPLETE_GENOMICS	ss162207185	Jul 04, 2010 (132)
40	COMPLETE_GENOMICS	ss163486146	Jul 04, 2010 (132)
41	COMPLETE_GENOMICS	ss166657856	Jul 04, 2010 (132)
42	ILLUMINA	ss170621588	Jul 04, 2010 (132)
43	ILLUMINA	ss172565847	Jul 04, 2010 (132)
44	AFFY	ss172705960	Jul 04, 2010 (132)
45	BUSHMAN	ss202624630	Jul 04, 2010 (132)
46	BCM-HGSC-SUB	ss206020830	Jul 04, 2010 (132)
47	1000GENOMES	ss220179700	Jul 14, 2010 (132)
48	1000GENOMES	ss231851971	Jul 14, 2010 (132)
49	1000GENOMES	ss239259063	Jul 15, 2010 (132)
50	BL	ss253142337	May 09, 2011 (134)
51	GMI	ss277155057	May 04, 2012 (137)
52	PJP	ss292811157	May 09, 2011 (134)
53	PAGE_STUDY	ss469414423	May 04, 2012 (137)
54	ILLUMINA	ss480021754	May 04, 2012 (137)
55	ILLUMINA	ss480030521	May 04, 2012 (137)
56	ILLUMINA	ss480692573	Sep 08, 2015 (146)
57	ILLUMINA	ss484809050	May 04, 2012 (137)
58	EXOME_CHIP	ss491341959	May 04, 2012 (137)
59	ILLUMINA	ss536889672	Sep 08, 2015 (146)
60	TISHKOFF	ss556665702	Apr 25, 2013 (138)
61	SSMP	ss650345820	Apr 25, 2013 (138)
62	ILLUMINA	ss778437416	Sep 08, 2015 (146)
63	ILLUMINA	ss782851092	Sep 08, 2015 (146)
64	ILLUMINA	ss783815630	Sep 08, 2015 (146)
65	ILLUMINA	ss825410207	Jul 19, 2016 (147)
66	ILLUMINA	ss832104970	Sep 08, 2015 (146)
67	ILLUMINA	ss832794157	Jul 13, 2019 (153)
68	ILLUMINA	ss833892929	Sep 08, 2015 (146)
69	EVA-GONL	ss978675261	Aug 21, 2014 (142)
70	JMKIDD_LAB	ss1070470501	Aug 21, 2014 (142)
71	1000GENOMES	ss1304320658	Aug 21, 2014 (142)
72	DDI	ss1429444162	Apr 01, 2015 (144)
73	EVA_GENOME_DK	ss1579995533	Apr 01, 2015 (144)
74	EVA_DECODE	ss1588147619	Apr 01, 2015 (144)
75	EVA_UK10K_ALSPAC	ss1607241106	Apr 01, 2015 (144)
76	EVA_UK10K_TWINSUK	ss1650235139	Apr 01, 2015 (144)
77	EVA_SVP	ss1712582345	Apr 01, 2015 (144)
78	ILLUMINA	ss1752479760	Sep 08, 2015 (146)
79	HAMMER_LAB	ss1799389605	Sep 08, 2015 (146)
80	WEILL_CORNELL_DGM	ss1921912785	Feb 12, 2016 (147)
81	GENOMED	ss1969410923	Jul 19, 2016 (147)
82	JJLAB	ss2021516563	Sep 14, 2016 (149)
83	USC_VALOUEV	ss2149591506	Dec 20, 2016 (150)
84	HUMAN_LONGEVITY	ss2252240444	Dec 20, 2016 (150)
85	SYSTEMSBIOZJU	ss2625256503	Nov 08, 2017 (151)
86	ILLUMINA	ss2633960037	Nov 08, 2017 (151)
87	ILLUMINA	ss2633960038	Nov 08, 2017 (151)
88	ILLUMINA	ss2633960039	Nov 08, 2017 (151)
89	GRF	ss2704968623	Nov 08, 2017 (151)
90	ILLUMINA	ss2710974693	Nov 08, 2017 (151)
91	GNOMAD	ss2793861866	Nov 08, 2017 (151)
92	AFFY	ss2985260181	Nov 08, 2017 (151)
93	SWEGEN	ss2992441087	Nov 08, 2017 (151)
94	ILLUMINA	ss3022248512	Nov 08, 2017 (151)
95	BIOINF_KMB_FNS_UNIBA	ss3024521406	Nov 08, 2017 (151)
96	CSHL	ss3345055089	Nov 08, 2017 (151)
97	ILLUMINA	ss3628680412	Oct 12, 2018 (152)
98	ILLUMINA	ss3631905603	Oct 12, 2018 (152)
99	ILLUMINA	ss3633295159	Oct 12, 2018 (152)
100	ILLUMINA	ss3634012322	Oct 12, 2018 (152)
101	ILLUMINA	ss3634899713	Oct 12, 2018 (152)
102	ILLUMINA	ss3635696205	Oct 12, 2018 (152)
103	ILLUMINA	ss3636594993	Oct 12, 2018 (152)
104	ILLUMINA	ss3637448585	Oct 12, 2018 (152)
105	ILLUMINA	ss3638420008	Oct 12, 2018 (152)
106	ILLUMINA	ss3639212894	Oct 12, 2018 (152)
107	ILLUMINA	ss3639624537	Oct 12, 2018 (152)
108	ILLUMINA	ss3640607014	Oct 12, 2018 (152)
109	ILLUMINA	ss3643376639	Oct 12, 2018 (152)
110	URBANLAB	ss3647420346	Oct 12, 2018 (152)
111	ILLUMINA	ss3652724724	Oct 12, 2018 (152)
112	ILLUMINA	ss3654028664	Oct 12, 2018 (152)
113	EGCUT_WGS	ss3660368442	Jul 13, 2019 (153)
114	EVA_DECODE	ss3709387299	Jul 13, 2019 (153)
115	ILLUMINA	ss3726023806	Jul 13, 2019 (153)
116	ACPOP	ss3729954134	Jul 13, 2019 (153)
117	ILLUMINA	ss3744512242	Jul 13, 2019 (153)
118	ILLUMINA	ss3745199686	Jul 13, 2019 (153)
119	EVA	ss3760130887	Jul 13, 2019 (153)
120	ILLUMINA	ss3772695101	Jul 13, 2019 (153)
121	PACBIO	ss3784335566	Jul 13, 2019 (153)
122	PACBIO	ss3789847994	Jul 13, 2019 (153)
123	PACBIO	ss3794722033	Jul 13, 2019 (153)
124	KHV_HUMAN_GENOMES	ss3803264403	Jul 13, 2019 (153)
125	EVA	ss3827849141	Apr 25, 2020 (154)
126	EVA	ss3837348213	Apr 25, 2020 (154)
127	EVA	ss3842774269	Apr 25, 2020 (154)
128	HGDP	ss3847710550	Apr 25, 2020 (154)
129	SGDP_PRJ	ss3856009599	Apr 25, 2020 (154)
130	KRGDB	ss3901881048	Apr 25, 2020 (154)
131	KOGIC	ss3951425540	Apr 25, 2020 (154)
132	EVA	ss3984509003	Apr 27, 2021 (155)
133	EVA	ss3984996682	Apr 27, 2021 (155)
134	EVA	ss4017085484	Apr 27, 2021 (155)
135	TOPMED	ss4567447631	Apr 27, 2021 (155)
136	TOMMO_GENOMICS	ss5159518447	Apr 27, 2021 (155)
137	1000G_HIGH_COVERAGE	ss5254362635	Oct 12, 2022 (156)
138	EVA	ss5314862721	Oct 12, 2022 (156)
139	EVA	ss5340323235	Oct 12, 2022 (156)
140	HUGCELL_USP	ss5453722463	Oct 12, 2022 (156)
141	1000G_HIGH_COVERAGE	ss5532871341	Oct 12, 2022 (156)
142	SANFORD_IMAGENETICS	ss5624520600	Oct 12, 2022 (156)
143	SANFORD_IMAGENETICS	ss5632284333	Oct 12, 2022 (156)
144	TOMMO_GENOMICS	ss5691287792	Oct 12, 2022 (156)
145	EVA	ss5799580888	Oct 12, 2022 (156)
146	YY_MCH	ss5803805483	Oct 12, 2022 (156)
147	EVA	ss5825864101	Oct 12, 2022 (156)
148	EVA	ss5853643275	Oct 12, 2022 (156)
149	EVA	ss5869154967	Oct 12, 2022 (156)
150	EVA	ss5960586362	Oct 12, 2022 (156)
151	EVA	ss5980151287	Oct 12, 2022 (156)
152	1000Genomes	NC_000003.11 - 64078009	Oct 12, 2018 (152)
153	1000Genomes_30x	NC_000003.12 - 64092333	Oct 12, 2022 (156)
154	The Avon Longitudinal Study of Parents and Children	NC_000003.11 - 64078009	Oct 12, 2018 (152)
155	Genetic variation in the Estonian population	NC_000003.11 - 64078009	Oct 12, 2018 (152)
156	The Danish reference pan genome	NC_000003.11 - 64078009	Apr 25, 2020 (154)
157	gnomAD - Genomes	NC_000003.12 - 64092333	Apr 27, 2021 (155)
158	Genome of the Netherlands Release 5	NC_000003.11 - 64078009	Apr 25, 2020 (154)
159	HGDP-CEPH-db Supplement 1	NC_000003.10 - 64053049	Apr 25, 2020 (154)
160	HapMap	NC_000003.12 - 64092333	Apr 25, 2020 (154)
161	KOREAN population from KRGDB	NC_000003.11 - 64078009	Apr 25, 2020 (154)
162	Korean Genome Project	NC_000003.12 - 64092333	Apr 25, 2020 (154)
163	Northern Sweden	NC_000003.11 - 64078009	Jul 13, 2019 (153)
164	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000003.11 - 64078009	Apr 27, 2021 (155)
165	CNV burdens in cranial meningiomas	NC_000003.11 - 64078009	Apr 27, 2021 (155)
166	Qatari	NC_000003.11 - 64078009	Apr 25, 2020 (154)
167	SGDP_PRJ	NC_000003.11 - 64078009	Apr 25, 2020 (154)
168	Siberian	NC_000003.11 - 64078009	Apr 25, 2020 (154)
169	8.3KJPN	NC_000003.11 - 64078009	Apr 27, 2021 (155)
170	14KJPN	NC_000003.12 - 64092333	Oct 12, 2022 (156)
171	TopMed	NC_000003.12 - 64092333	Apr 27, 2021 (155)
172	UK 10K study - Twins	NC_000003.11 - 64078009	Oct 12, 2018 (152)
173	A Vietnamese Genetic Variation Database	NC_000003.11 - 64078009	Jul 13, 2019 (153)
174	ALFA	NC_000003.12 - 64092333	Apr 27, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs56897911	May 23, 2008 (130)
rs386536287	Aug 21, 2014 (142)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
9058442, ss3901881048	NC_000003.11:64078008:C:G	NC_000003.12:64092332:C:G	(self)
ss83579866, ss84047385, ss3639212894, ss3639624537	NC_000003.9:64053048:C:T	NC_000003.12:64092332:C:T	(self)
388442, ss92116166, ss110265635, ss111833060, ss117110476, ss162207185, ss163486146, ss166657856, ss202624630, ss206020830, ss253142337, ss277155057, ss292811157, ss480021754, ss825410207, ss1588147619, ss1712582345, ss3643376639, ss3847710550	NC_000003.10:64053048:C:T	NC_000003.12:64092332:C:T	(self)
15519238, 8637085, 6106690, 6160472, 3788181, 9058442, 3238999, 222609, 58350, 3954715, 8026579, 2107860, 17487754, 8637085, 1875330, ss220179700, ss231851971, ss239259063, ss480030521, ss480692573, ss484809050, ss491341959, ss536889672, ss556665702, ss650345820, ss778437416, ss782851092, ss783815630, ss832104970, ss832794157, ss833892929, ss978675261, ss1070470501, ss1304320658, ss1429444162, ss1579995533, ss1607241106, ss1650235139, ss1752479760, ss1799389605, ss1921912785, ss1969410923, ss2021516563, ss2149591506, ss2625256503, ss2633960037, ss2633960038, ss2633960039, ss2704968623, ss2710974693, ss2793861866, ss2985260181, ss2992441087, ss3022248512, ss3345055089, ss3628680412, ss3631905603, ss3633295159, ss3634012322, ss3634899713, ss3635696205, ss3636594993, ss3637448585, ss3638420008, ss3640607014, ss3652724724, ss3654028664, ss3660368442, ss3729954134, ss3744512242, ss3745199686, ss3760130887, ss3772695101, ss3784335566, ss3789847994, ss3794722033, ss3827849141, ss3837348213, ss3856009599, ss3901881048, ss3984509003, ss3984996682, ss4017085484, ss5159518447, ss5314862721, ss5340323235, ss5624520600, ss5632284333, ss5799580888, ss5825864101, ss5960586362, ss5980151287	NC_000003.11:64078008:C:T	NC_000003.12:64092332:C:T	(self)
20397276, 110136208, 2375473, 7803541, 25124896, 404825186, 8680538861, ss2252240444, ss3024521406, ss3647420346, ss3709387299, ss3726023806, ss3803264403, ss3842774269, ss3951425540, ss4567447631, ss5254362635, ss5453722463, ss5532871341, ss5691287792, ss5803805483, ss5853643275, ss5869154967	NC_000003.12:64092332:C:T	NC_000003.12:64092332:C:T	(self)
ss10099059	NT_005999.15:13015869:C:T	NC_000003.12:64092332:C:T	(self)
ss22018571	NT_022517.16:64000346:C:T	NC_000003.12:64092332:C:T	(self)
ss321510, ss331366, ss1141300, ss1141920, ss1787629, ss1787800, ss2154042, ss3253545, ss3606747, ss23910531, ss44419208, ss66147290, ss66830505, ss67127834, ss67467093, ss70441223, ss70629848, ss71179738, ss75883690, ss76171866, ss83369259, ss99098273, ss103944443, ss121741030, ss135280123, ss138904595, ss153499707, ss155570394, ss159282020, ss160368793, ss170621588, ss172565847, ss172705960, ss469414423	NT_022517.18:64018008:C:T	NC_000003.12:64092332:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

3 citations for rs153734

PMID	Title	Author	Year	Journal
19303062	Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.	Tanaka T et al.	2009	American journal of human genetics
19744961	Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.	Hazra A et al.	2009	Human molecular genetics
27901035	Homocysteine-reducing B vitamins and ischemic heart disease: a separate-sample Mendelian randomization analysis.	Zhao JV et al.	2017	European journal of clinical nutrition

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs153734