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Amino Acid Substitution

The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

Year introduced: 1998

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Tree Number(s): E05.393.420.601.035, G05.558.109

MeSH Unique ID: D019943

Entry Terms:

  • Amino Acid Substitutions
  • Substitution, Amino Acid
  • Substitutions, Amino Acid

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