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Acute renal failure due to ischemia

MedGen UID:
742017
•Concept ID:
C1828256
•
Disease or Syndrome
Synonym: Acute ischemic renal failure
SNOMED CT: Acute renal failure due to ischemia (423533009); Acute ischemic renal failure (423533009)

Professional guidelines

PubMed

AGA Clinical Practice Update on the Evaluation and Management of Acute Kidney Injury in Patients With Cirrhosis: Expert Review.
Flamm SL, Wong F, Ahn J, Kamath PS
Clin Gastroenterol Hepatol 2022 Dec;20(12):2707-2716. Epub 2022 Sep 6 doi: 10.1016/j.cgh.2022.08.033. PMID: 36075500
Management of Acute Liver Failure: Update 2022.
Tujios S, Stravitz RT, Lee WM
Semin Liver Dis 2022 Aug;42(3):362-378. Epub 2022 Aug 24 doi: 10.1055/s-0042-1755274. PMID: 36001996Free PMC Article
Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association.
Topjian AA, de Caen A, Wainwright MS, Abella BS, Abend NS, Atkins DL, Bembea MM, Fink EL, Guerguerian AM, Haskell SE, Kilgannon JH, Lasa JJ, Hazinski MF
Circulation 2019 Aug 6;140(6):e194-e233. Epub 2019 Jun 27 doi: 10.1161/CIR.0000000000000697. PMID: 31242751

Recent clinical studies

Etiology

Acute Kidney Injury by Ischemia/Reperfusion and Extracellular Vesicles.
Nørgård MØ, Svenningsen P
Int J Mol Sci 2023 Oct 18;24(20) doi: 10.3390/ijms242015312. PMID: 37894994Free PMC Article
High-Density Lipoproteins and Acute Kidney Injury.
Smith LE
Semin Nephrol 2020 Mar;40(2):232-242. doi: 10.1016/j.semnephrol.2020.01.013. PMID: 32303285
Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.
Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374Free PMC Article
Pathophysiology of ischemic acute kidney injury.
Sharfuddin AA, Molitoris BA
Nat Rev Nephrol 2011 Apr;7(4):189-200. Epub 2011 Mar 1 doi: 10.1038/nrneph.2011.16. PMID: 21364518
Acute renal failure.
Agrawal M, Swartz R
Am Fam Physician 2000 Apr 1;61(7):2077-88. PMID: 10779250

Diagnosis

Renal Endothelial Cell-Targeted Extracellular Vesicles Protect the Kidney from Ischemic Injury.
Zhang K, Li R, Chen X, Yan H, Li H, Zhao X, Huang H, Chen S, Liu Y, Wang K, Han Z, Han ZC, Kong D, Chen XM, Li Z
Adv Sci (Weinh) 2023 Jan;10(3):e2204626. Epub 2022 Nov 23 doi: 10.1002/advs.202204626. PMID: 36416304Free PMC Article
Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.
Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374Free PMC Article
Acute kidney injury in severe sepsis: pathophysiology, diagnosis, and treatment recommendations.
Keir I, Kellum JA
J Vet Emerg Crit Care (San Antonio) 2015 Mar-Apr;25(2):200-9. doi: 10.1111/vec.12297. PMID: 25845505
Pathophysiology of acute kidney injury.
Basile DP, Anderson MD, Sutton TA
Compr Physiol 2012 Apr;2(2):1303-53. doi: 10.1002/cphy.c110041. PMID: 23798302Free PMC Article
Cocaine intoxication.
Zimmerman JL
Crit Care Clin 2012 Oct;28(4):517-26. Epub 2012 Aug 30 doi: 10.1016/j.ccc.2012.07.003. PMID: 22998988

Therapy

Regulated necrosis in kidney ischemia-reperfusion injury.
Pefanis A, Ierino FL, Murphy JM, Cowan PJ
Kidney Int 2019 Aug;96(2):291-301. Epub 2019 Mar 7 doi: 10.1016/j.kint.2019.02.009. PMID: 31005270
Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.
Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374Free PMC Article
PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM
Nature 2016 Mar 24;531(7595):528-32. Epub 2016 Mar 16 doi: 10.1038/nature17184. PMID: 26982719Free PMC Article
Acute kidney injury in severe sepsis: pathophysiology, diagnosis, and treatment recommendations.
Keir I, Kellum JA
J Vet Emerg Crit Care (San Antonio) 2015 Mar-Apr;25(2):200-9. doi: 10.1111/vec.12297. PMID: 25845505
Cocaine intoxication.
Zimmerman JL
Crit Care Clin 2012 Oct;28(4):517-26. Epub 2012 Aug 30 doi: 10.1016/j.ccc.2012.07.003. PMID: 22998988

Prognosis

Renal Endothelial Cell-Targeted Extracellular Vesicles Protect the Kidney from Ischemic Injury.
Zhang K, Li R, Chen X, Yan H, Li H, Zhao X, Huang H, Chen S, Liu Y, Wang K, Han Z, Han ZC, Kong D, Chen XM, Li Z
Adv Sci (Weinh) 2023 Jan;10(3):e2204626. Epub 2022 Nov 23 doi: 10.1002/advs.202204626. PMID: 36416304Free PMC Article
Crosstalk between gut microbiota and renal ischemia/reperfusion injury.
Huang P, Cao J, Chen J, Luo Y, Gong X, Wu C, Wang Y
Front Cell Infect Microbiol 2022;12:1015825. Epub 2022 Sep 5 doi: 10.3389/fcimb.2022.1015825. PMID: 36132990Free PMC Article
Acute Kidney Injury in Cardiac Surgery.
Massoth C, Zarbock A, Meersch M
Crit Care Clin 2021 Apr;37(2):267-278. Epub 2021 Feb 13 doi: 10.1016/j.ccc.2020.11.009. PMID: 33752855
What a Nephrologist Needs to Know About Acute Liver Failure.
Leventhal TM, Liu KD
Adv Chronic Kidney Dis 2015 Sep;22(5):376-81. doi: 10.1053/j.ackd.2015.06.006. PMID: 26311599
Pathophysiology of acute kidney injury.
Basile DP, Anderson MD, Sutton TA
Compr Physiol 2012 Apr;2(2):1303-53. doi: 10.1002/cphy.c110041. PMID: 23798302Free PMC Article

Clinical prediction guides

HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
Shi L, Song Z, Li C, Deng F, Xia Y, Huang J, Wu X, Zhu J
Cells 2022 Dec 7;11(24) doi: 10.3390/cells11243951. PMID: 36552715Free PMC Article
Ischemic Preconditioning of the Kidney.
Plotnikov EY
Bull Exp Biol Med 2021 Sep;171(5):567-571. Epub 2021 Oct 7 doi: 10.1007/s10517-021-05270-9. PMID: 34617172
Ischemic acute kidney injury and klotho in renal transplantation.
Panah F, Ghorbanihaghjo A, Argani H, Asadi Zarmehri M, Nazari Soltan Ahmad S
Clin Biochem 2018 May;55:3-8. Epub 2018 Mar 31 doi: 10.1016/j.clinbiochem.2018.03.022. PMID: 29608890
Renal haemodynamics and oxygenation during and after cardiac surgery and cardiopulmonary bypass.
Evans RG, Lankadeva YR, Cochrane AD, Marino B, Iguchi N, Zhu MZL, Hood SG, Smith JA, Bellomo R, Gardiner BS, Lee CJ, Smith DW, May CN
Acta Physiol (Oxf) 2018 Mar;222(3) Epub 2017 Nov 30 doi: 10.1111/apha.12995. PMID: 29127739
AKI in the ICU: definition, epidemiology, risk stratification, and outcomes.
Singbartl K, Kellum JA
Kidney Int 2012 May;81(9):819-25. Epub 2011 Oct 5 doi: 10.1038/ki.2011.339. PMID: 21975865

Recent systematic reviews

Association of SGLT2 inhibitors with cardiovascular, kidney, and safety outcomes among patients with diabetic kidney disease: a meta-analysis.
Kaze AD, Zhuo M, Kim SC, Patorno E, Paik JM
Cardiovasc Diabetol 2022 Mar 23;21(1):47. doi: 10.1186/s12933-022-01476-x. PMID: 35321742Free PMC Article
Advances in Neonatal Acute Kidney Injury.
Starr MC, Charlton JR, Guillet R, Reidy K, Tipple TE, Jetton JG, Kent AL, Abitbol CL, Ambalavanan N, Mhanna MJ, Askenazi DJ, Selewski DT, Harer MW; Neonatal Kidney Collaborative Board
Pediatrics 2021 Nov;148(5) Epub 2021 Oct 1 doi: 10.1542/peds.2021-051220. PMID: 34599008
Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials.
Nagendran M, Russell JA, Walley KR, Brett SJ, Perkins GD, Hajjar L, Mason AJ, Ashby D, Gordon AC
Intensive Care Med 2019 Jun;45(6):844-855. Epub 2019 May 6 doi: 10.1007/s00134-019-05620-2. PMID: 31062052
Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review.
Wesselink EM, Kappen TH, Torn HM, Slooter AJC, van Klei WA
Br J Anaesth 2018 Oct;121(4):706-721. Epub 2018 Jun 20 doi: 10.1016/j.bja.2018.04.036. PMID: 30236233
Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.
Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374Free PMC Article

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