Format

Send to

Choose Destination
Crit Care Clin. 2012 Oct;28(4):517-26. doi: 10.1016/j.ccc.2012.07.003. Epub 2012 Aug 30.

Cocaine intoxication.

Author information

1
Department of Medicine, Weill Cornell Medical College, New York, NY, USA. janicez@tmhs.org

Abstract

Cocaine, a natural alkaloid derived from the coca plant, is one of the most commonly abused illicit drugs. Cocaine is commonly abused by inhalation, nasal insufflation, and intravenous injection, resulting in many adverse effects that ensue from local anesthetic, vasoconstrictive, sympathomimetic, psychoactive, and prothrombotic mechanisms. Cocaine can affect all body systems and the clinical presentation may primarily result from organ toxicity. Among the most severe complications are seizures, hemorrhagic and ischemic strokes, myocardial infarction, aortic dissection, rhabdomyolysis, mesenteric ischemia, acute renal injury and multiple organ failure.

PMID:
22998988
DOI:
10.1016/j.ccc.2012.07.003
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center