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Sarcomatous intrahepatic cholangiocarcinoma

MedGen UID:
275403
•Concept ID:
C1519184
•
Neoplastic Process
Synonyms: Intrahepatic Cholangiocarcinoma with Extensive Sarcomatous Changes; intrahepatic cholangiocarcinoma with extensive sarcomatous changes; Sarcomatoid Intrahepatic Cholangiocarcinoma; sarcomatoid intrahepatic cholangiocarcinoma; Sarcomatous Intrahepatic Cholangiocarcinoma; sarcomatous intrahepatic cholangiocarcinoma
 
Monarch Initiative: MONDO:0004451

Definition

A rare, aggressive variant of intrahepatic cholangiocarcinoma. It is characterized by the presence of adenocarcinoma cells that are intermingled with malignant pleomorphic spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSarcomatous intrahepatic cholangiocarcinoma

Recent clinical studies

Etiology

Sarcomatous carcinoma in biliary system: A retrospective study.
Zhang N, Li Y, Zhao M, Chang X, Qu Q, He X
Medicine (Baltimore) 2019 Feb;98(8):e14585. doi: 10.1097/MD.0000000000014585. PMID: 30813178Free PMC Article
Imaging features of hepatic sarcomatous carcinoma on computed tomography and gadoxetic acid-enhanced magnetic resonance imaging.
Gu KW, Kim YK, Min JH, Ha SY, Jeong WK
Abdom Radiol (NY) 2017 May;42(5):1424-1433. doi: 10.1007/s00261-016-1038-7. PMID: 28078380

Diagnosis

Imaging and clinical features of primary hepatic sarcomatous carcinoma.
Shi D, Ma L, Zhao D, Chang J, Shao C, Qi S, Chen F, Li Y, Wang X, Zhang Y, Zhao J, Li H
Cancer Imaging 2018 Oct 12;18(1):36. doi: 10.1186/s40644-018-0171-7. PMID: 30314525Free PMC Article
Sarcomatous intrahepatic cholangiocarcinoma: Case report and literature review.
Zhang N, Li Y, Zhao M, Chang X, Tian F, Qu Q, He X
Medicine (Baltimore) 2018 Sep;97(39):e12549. doi: 10.1097/MD.0000000000012549. PMID: 30278551Free PMC Article

Prognosis

Sarcomatous carcinoma in biliary system: A retrospective study.
Zhang N, Li Y, Zhao M, Chang X, Qu Q, He X
Medicine (Baltimore) 2019 Feb;98(8):e14585. doi: 10.1097/MD.0000000000014585. PMID: 30813178Free PMC Article
Imaging and clinical features of primary hepatic sarcomatous carcinoma.
Shi D, Ma L, Zhao D, Chang J, Shao C, Qi S, Chen F, Li Y, Wang X, Zhang Y, Zhao J, Li H
Cancer Imaging 2018 Oct 12;18(1):36. doi: 10.1186/s40644-018-0171-7. PMID: 30314525Free PMC Article
Sarcomatous intrahepatic cholangiocarcinoma: Case report and literature review.
Zhang N, Li Y, Zhao M, Chang X, Tian F, Qu Q, He X
Medicine (Baltimore) 2018 Sep;97(39):e12549. doi: 10.1097/MD.0000000000012549. PMID: 30278551Free PMC Article
Prognosis analysis of sarcomatous intrahepatic cholangiocarcinoma from a review of the literature.
Watanabe G, Uchinami H, Yoshioka M, Nanjo H, Yamamoto Y
Int J Clin Oncol 2014;19(3):490-6. Epub 2013 Jul 4 doi: 10.1007/s10147-013-0586-x. PMID: 23824556

Clinical prediction guides

Imaging features of hepatic sarcomatous carcinoma on computed tomography and gadoxetic acid-enhanced magnetic resonance imaging.
Gu KW, Kim YK, Min JH, Ha SY, Jeong WK
Abdom Radiol (NY) 2017 May;42(5):1424-1433. doi: 10.1007/s00261-016-1038-7. PMID: 28078380

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