1QE3_A 2 THQIVTTQY-----------------GKVKGTTENGVHKWKGIPYAKPPVGQWRFKAPEPPE-VWEDVLDATAYGPICPQ 63 Bacillus subtilis 19552359 1 ------------------------------------------------------------------------MFGEVASQ 8 Corynebacterium glu... 19553499 1 ---------------------------------MSATSSVTVECPAGTITGEPHYFRSIPYA-KARPFADAEKLEPLRID 46 Corynebacterium glu... 15805442 19 AAPQLRVEQ-----------------GTLNGKAVNSVQQFLGVPFAAPPVGPLRWQPPQPP--VWSGQRDATQFGPACAQ 79 Deinococcus radiodu... 15807606 25 SAPVSTSATpastaapaaparvqapaGTFVGQDRAGVRSWLGIPYAQPPVGDARWQPPRALP-ASQAERTTTQPGAACVQ 103 Deinococcus radiodu... 15841533 4 RTVRARTAT-----------------GIVEGFTRDGVHRWRSIPYARAPVGSLRFRAPQPAQ-PWPGVRHCHTFANCAPQ 65 Mycobacterium tuber... 17547312 1 ---------------------------MNADTAVHSVRSWLGIPYAT----AERFRRPALL--PFAPERSYDQKGPAPLQ 47 Ralstonia solanacearum 15609182 14 RTVRARTAT-----------------GIVEGFTRDGVHRWRSIPYARAPVGSLRFRAPQPAQ-PWPGVRHCHTFANCAPQ 75 Mycobacterium tuber... 15928030 1 --MKINTTG-----------------GQIHGITQDGLDIFLGIPYAEPPVHDNRFKHSTLKT-QWSEPIDATEIQPIPPQ 60 Staphylococcus aure... 19075789 1 -MGVLHGLT------------------VLDENGKEKCHRFTGIRYAKPPVGKLRWRRPVTLEdGYDYSGDYNQFKTICPQ 61 fission yeast
1QE3_A 64 PSDl-lSLSYTE--LPRQSEDCLYVNVFAPD--TPSQN-LPVMVWIHGGAFYLGAGSEP-LYDGSKLAAQGE---VIVVT 133 Bacillus subtilis 19552359 9 P-----TYSWTD--KIRGSEDCLNLDVVRPD---SEEK-LPVVVYLHGGSFIMGSSSEK-ALRGYNLVTNMN---VVYVS 73 Corynebacterium glu... 19553499 47 A---------------TGKHEGLYLTLATPEarFGADA--PVIVYIHGGGYDGGTRFDA-RTEPTFFREQG----FVVVS 104 Corynebacterium glu... 15805442 80 G-------------D-GGSEDCLTLNIYRPP---NAKN-APLLVWVHGGFFTGGDASL---FDGSALARERG---VVVAT 135 Deinococcus radiodu... 15807606 104 TLSv---pGMDK--QVRGAEDCLFLNVYAPT---NAQK-APVMVWIHGGSFQMGAGSD---YDLSVLAREQG---VVAVS 168 Deinococcus radiodu... 15841533 66 QRRy-tVMGIGR--YQTRSEDCLTLNVVTPE--EPATQpLPVMVFIHGGGYILGSSATP-IYDGAALARRG----CVYVS 135 Mycobacterium tuber... 17547312 48 AG-----DTRWLeaDNGLSEDCLNLNIWAPEd-VCEEP-LPVIVYIFGGGFEMGANTQT-TSNLSGLAATGR---AIGVS 116 Ralstonia solanacearum 15609182 76 QRRy-tVMGIGR--YQTRSEDCLTLNVVTPE--EPATQpLPVMVFIHGGGYILGSSATP-IYDGAALARRG----CVYVS 145 Mycobacterium tuber... 15928030 61 PDNkleDFFSSQstTFTEHEDCLYLNIWKQHn--DQTK-KPVIIYFYGGSFENGHGTAE-LYQPAHLVQNND---IIVIT 133 Staphylococcus aure... 19075789 62 PFYn-nRKNQVRnpDFKYDEDCLFLNIWVPAgeKPAEG-WPVLYFIHGGWLQVGNPLHYrQCDPQDLQADGSpakFILVS 139 fission yeast
1QE3_A 134 LNYRLGPFGFLHLSSFD--EAYSDN-LGLLDQAAALKWVRENISAFGGDPDNVTVFGESAGGMSIAALLAM----PAAKG 206 Bacillus subtilis 19552359 74 VNFRLGALGYLDLRSVG--EDCVAN-PALHDQLLALQWVSRNIEAFGGDPDNVTLMGESAGAAAVVALMCV----PAAGG 146 Corynebacterium glu... 19553499 105 IDYRVGLEGFARFHDDEanRYR-----GIDDCVLALEWVQKNIEHFGGDPTNVTLIGQSAGAGIALWLTRL----DHYKG 175 Corynebacterium glu... 15805442 136 VNYRLGLYGFLAVPGVT--DG---N-AGLYDILGAVRWLKQNAASIGADPGNITLAGQSAGAAAICTLLAA----PSAAG 205 Deinococcus radiodu... 15807606 169 LNYRLGALGFLATPALDtaQGTAGN-LGLLDQQLALKWVRDNIAAFGGDAQNVTVFGESAGGMSICAQLAS----PGAAG 243 Deinococcus radiodu... 15841533 136 VNYRLGALGCLDLSSLStpQITLDSnVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAV----PAAKG 211 Mycobacterium tuber... 17547312 117 LNYRLGPFGWLSLSQYGgvFADATN-LGLQDIIAALQWVRENITHFGGDPQNVTVTGHSAGAYATIGLLAA----PSADG 191 Ralstonia solanacearum 15609182 146 VNYRLGALGCLDLSSLStpQITLDSnVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAV----PAAKG 221 Mycobacterium tuber... 15928030 134 CNYRLGALGYLDWSYFN--KDFHSN-NGLSDQINVIKWVHQFIESFGGDANNITLMGQSAGSMSILTLLKI----PDIEP 206 Staphylococcus aure... 19075789 140 PGHRLNLFGFLAGKELLeeDPKSSN-FGFWDQRLGLEWTYKHIESFGGNKENIAVGGISAGSYSALFQLIYetyhPEANQ 218 fission yeast
1QE3_A 207 LFQKAIMESGAS----RTMTKEQAASTAAAFLQVLGIN-----ESQLDRLHTVAAEDLLKAADQLRIAEkeniFQLF-FQ 276 Bacillus subtilis 19552359 147 LFHRAIAQSAPVi---SVHSSTQAKFWARELIYRMALPr----ETTLDELRQESADDLVRAGQSMMWRSgellQLNScYG 219 Corynebacterium glu... 19553499 176 AFRRLVALSPSFp-------RQPFAARKGALRRALGKP------VTRASLAGIKPARLDKGYRRFARR----------YF 232 Corynebacterium glu... 15805442 206 LFQKAILQSGSCaapiFQTPLGDARRKGELFSRALRCDr----GETATCLRGKSRAELDGVRLTGRGP-----VDPVpLP 276 Deinococcus radiodu... 15807606 244 LFDKAIIQSGPCtapgIMQSRAEAYNLGSRFAAAVGCD-----PADAACLRAVPADKLVLTRSPNAAFP-----GAVpFP 313 Deinococcus radiodu... 15841533 212 LFARAISESPAAg---MVRSREVAAEFAARFANLIGARt----QDAANALMQASPAQLVEAQHHLIRQGmrkrLGAFpIG 284 Mycobacterium tuber... 17547312 192 LYRRLAAFSGGAs---RIVPAWWAEELAIKVLTELGIAdd--pERLLTVDGKLLAETLIKVSPRDIGDRhgidNTTIgIV 266 Ralstonia solanacearum 15609182 222 LFARAISESPAAg---MVRSREVAAEFAARFANLIGARt----QDAANALMQASPAQLVEAQHHLIRQGmrkrLGAFpIG 294 Mycobacterium tuber... 15928030 207 YFHKVVLLSGALr----LDTLKSARNKAQYFQKMMRDY------LDTDDVTSLSTDDILMLMAKLKQS------R---GP 267 Staphylococcus aure... 19075789 219 IIKRALLLSNGLs--vQPKSVEESQIQFNELAQKFGIPlelssAEKLEKLRAIPFQDLADNILNLRLHT----FRAVtDG 292 fission yeast
1QE3_A 277 PALDPK--TLPEEPEKSIAEGAASGIPLLIGTTRDEGYLFFTPDSDvHSQETLDAALEYLLGKPLA------EKAADLYP 348 Bacillus subtilis 19552359 220 PTVDGS--LLPEHPLTMFEQGRQHRIPFMIGTNNGETSFSKAFYLR--SSARRRSALRMLSVYDPHn----aERVVSAYG 291 Corynebacterium glu... 19553499 233 TDLALG--PTPYDPNELADIDLIISSTRDEMYGHRAGLWFDQRGFG-------AKLAARLFGLENS---------DTYIK 294 Corynebacterium glu... 15805442 277 PVYGDA--LIPLRPQDAFAQGQSLKVAVMLGINREEGQIFEPYLPD----LLRGSRTLYRAGLTLInpl-qaWALGGRYP 349 Deinococcus radiodu... 15807606 314 PVYGDS--TVPRAPAEVLRQG-QNAVPLLIGTNLNEGTLFAAFVGD--P--RRDLNAAEFLGLNAVlngpnaPRALLAYN 386 Deinococcus radiodu... 15841533 285 PVFGDD--YLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLG--MLPTNEPMVEELLSGMKPAd----rERITAAYP 356 Mycobacterium tuber... 17547312 267 DDRWQTgaVLIDTPLHILASGRRRDVDILLSTATQEADWWVINAREkFDPGSIDKLVDELVVKSRIprs-raRRVAATYD 345 Ralstonia solanacearum 15609182 295 PVFGDD--YLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLG--MLPTNEPMVEELLSGMKPAd----rERITAAYP 366 Mycobacterium tuber... 15928030 268 SKGLDL--IYAPIKTDYIQNDYPTTKPIFACYTKDEGDIYITSEQ-------KKLSPQRFIDIMELn------DIPLKYE 332 Staphylococcus aure... 19075789 293 DFVNPNt-FKDIYDGTFGKRIRDSGRELIIGEVNNEHSIYANTNPPkSKEDLFNQVNNYYPEKVTKallelyPKVPDMED 371 fission yeast
1QE3_A 349 R------SLESQIHMMTDLLFWRPAVAYASAQS----HYAPVWMYRFDWH----------PEKPPYNKAFHALELPFVFG 408 Bacillus subtilis 19552359 292 Gg----eARTDFSELLADALFWAPSVRLAQSHAs---QDEDTWMYRFDYAp--------qSMRKLGLGAIHSFELNAVFG 356 Corynebacterium glu... 19553499 295 -------EARKIDNRVVGRMIGDAVIRRYVAQT------EKGWWMEFPGK--------------------HCDDLSLVFL 341 Corynebacterium glu... 15805442 350 Lrsd-eqPIRAVTRLLTDQVFACPTSWLAGKLG----AGLPTYFYEFSDPrppl--qlagKVNVPNLGAYHGAELAYVLD 422 Deinococcus radiodu... 15807606 387 Srts-gtRTQAAAASATDSLFACPSSNLARDIS----RFTPVYSYEFRDPnpprpaqlrpTVGVPSFGAFHGSEIVSVTG 461 Deinococcus radiodu... 15841533 357 Ny----pAPSACIQLGGDFAFSSAAWQIAEAHG----ANAPTYLYRYDYAp--------rTLRWSGFGATHATELFAVFD 420 Mycobacterium tuber... 17547312 346 Vng--raPVEVRGALFTDYFFTLPAARAALAHA-----AAGGSAHLLTVGp------------VEGAPAVHGTEMYGIVG 406 Ralstonia solanacearum 15609182 367 Ny----pAPSACIQLGGDFAFSSAAWQIAEAHG----ANAPTYLYRYDYAp--------rTLRWSGFGATHATELFAVFD 430 Mycobacterium tuber... 15928030 333 Dv----qTAKQQSLAITHCYFKQPMKQFLQHLNiq-dSNAQLWLAEFAWHd---------TSSAHYRSAYHILDMVFWFG 398 Staphylococcus aure... 19075789 372 EkeylaaIKALFGSIVSDMQVYASTRVLINGLVkggvPLEKIYRYRIAFRgkf-----fdKYEPPESLVPHAGDLGLWFY 446 fission yeast
1QE3_A 409 NLDglERMAKAEITDEV---KQLSHTIQSAWITFAKTGNPSTEAVN--WPAYHEETRETVILDS-EITIENDPESEKRQK 482 Bacillus subtilis 19552359 357 DHEssRSMNLAKIAGGMdhlDKVTELVQEHWKQFIYFGRPGEEWKAyrGRSDTEPGRATFVIDInS-RIAWDPRQDKRTA 435 Corynebacterium glu... 19553499 342 EDS-------------E---------AHHHIASFARGATPS-------WPQYSEENRAALSLVSgEAKVVKDPLRMVRLA 392 Corynebacterium glu... 15805442 423 TPVv-GVSDPAQFSSAQ---AKLAAQMGEYWTNFARSGQPASLGLTv-WPTFNPAFPQVMTLEPgATALKPNFDGRHQCD 497 Deinococcus radiodu... 15807606 462 TPS--GLGNPSDFTPAQ---AELSRTMQTYWANFARTGNPNGAGLPq-WAAFTTEQPQVLGLAPgEVTPVQDFRAEHHCD 535 Deinococcus radiodu... 15841533 421 IYR--TRFGALLTAAAD---RRAALRVSNEVQRRWRCFSQIGVPGDd-WPAYTQDDRAVLVFDR-RCRIEFDPHQHRRIA 493 Mycobacterium tuber... 17547312 407 QQR--PGRSDEQASRDT-------FVR-DALLHFAAGD-HDRl-----WKAVTTQSLSHGIGNP----P-YDPTTHAEEV 465 Ralstonia solanacearum 15609182 431 IYR--TRFGALLTAAAD---RRAALRVSNEVQRRWRCFSQIGVPGDd-WPAYTQDDRAVLVFDR-RCRIEFDPHQHRRIA 503 Mycobacterium tuber... 15928030 399 NLQilAAHQYPTTAHLK----FLSRQMQNDLANFAKSG-----KMP--WPMYHNERRYYRTYQ----------------- 450 Staphylococcus aure... 19075789 447 NVVdgILPEEIPIYKAW------LK-SYGEWMSTGKTD----------WGTTKTEEYRLLDADG-TIKVVDDEKWDWGLK 508 fission yeast
1QE3_A 483 LFPSKGE 489 Bacillus subtilis 19552359 436 WENYDML 442 Corynebacterium glutamicum ATCC 13032 19553499 393 F------ 393 Corynebacterium glutamicum ATCC 13032 15805442 498 YWNGAEG 504 Deinococcus radiodurans 15807606 536 TIWRP-- 540 Deinococcus radiodurans 15841533 494 WDGFSLA 500 Mycobacterium tuberculosis CDC1551 17547312 466 LQTFAGI 472 Ralstonia solanacearum 15609182 504 WDGFSLA 510 Mycobacterium tuberculosis H37Rv 15928030 ------- Staphylococcus aureus subsp. aureus N315 19075789 509 VGRTVAG 515 fission yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",