| H. pylori IgG antibody | |||
|---|---|---|---|
| Parameter | Positive (n = 65) | Negative (n = 20) | P value |
| Mean age | 49.9 | 48.5 | NS |
| No. (%) of patients with: | |||
| Mononuclear cell infiltration | 57 (88) | 4 (20) | <0.0001 |
| Polymorphonuclear cell infiltration | 45 (69) | 1 (5) | <0.0001 |
| Atrophic gastritis | 43 (66) | 2 (10) | <0.0001 |
| Intestinal metaplasia | 41 (63) | 0 (0) | <0.0001 |
| Mean (± SE) serum gastrin (pg/ml) | 114.3 ± 11.2 | 65.8 ± 6.5 | <0.03 |
| Mean (± SE) serum pepsinogen | |||
| PG I (ng/ml) | 61.1 ± 7.7 | 53.9 ± 3.4 | NS |
| PG II (ng/ml) | 19.3 ± 1.2 | 10.3 ± 1.6 | <0.0002 |
| PG I/II ratio | 3.1 ± 0.2 | 5.3 ± 0.4 | <0.0001 |
SE, standard error; NS, not significant. Reprinted from reference 4 with permission.
From: Chapter 40, Gastric Cancer
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