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sigma-54-dependent transcriptional regulator

sigma-54-dependent Fis family transcriptional regulator, similar to propionate catabolism operon regulatory protein PrpR, which has a role in regulating expression of enzymes involved in both glyoxylate and methylcitrate pathways

Arch. IDVersionDate PublishedReview Level
1207104422017-03-21
curated
Arch. ID12071044
Version2
Date Published2017-03-21
Review Level
curated
PrpR_N: Propionate catabolism activatorPrpR_NObsolete: This domain/cluster is obsoleteObsolete
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Sequences with this architecture
This architecture currently does not link to any protein sequence records.
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismssigma-54-dependent transcriptional regulatorsigma-54-dependent Fis family transcriptional regulator, similar to propionate catabolism operon regulatory protein PrpR, which has a role in regulating expression of enzymes involved in both glyoxylate and methylcitrate pathways
Name, label and taxonomic scope
Tax. ExpAll organisms
Namesigma-54-dependent transcriptional regulator
Labelsigma-54-dependent Fis family transcriptional regulator, similar to propionate catabolism operon regulatory protein PrpR, which has a role in regulating expression of enzymes involved in both glyoxylate and methylcitrate pathways
Supporting evidence
Comments
  • sigma-54 dependent activator family protein; activates the prpBCDE operon
  • The prpR gene is found in most cases divergently transcribed from an operon for the methylcitric acid cycle of propionate catabolism; 2-methylcitric acid, a catabolite by this pathway, is a coactivator of PrpR; part of the Fis family
  • sigma-54 dependent activator family protein; activates the prpBCDE operon
  • The prpR gene is found in most cases divergently transcribed from an operon for the methylcitric acid cycle of propionate catabolism; 2-methylcitric acid, a catabolite by this pathway, is a coactivator of PrpR; part of the Fis family
  • sigma-54 dependent activator family protein; activates the prpBCDE operon
  • The prpR gene is found in most cases divergently transcribed from an operon for the methylcitric acid cycle of propionate catabolism; 2-methylcitric acid, a catabolite by this pathway, is a coactivator of PrpR; part of the Fis family
CDD
  • cd00009: AAA
  • PRK15424: propionate catabolism operon regulatory protein PrpR; Provisional
  • TIGR02329: propionate_PrpR
  • pfam06506: PrpR_N : Propionate catabolism activator
  • pfam02954: HTH_8 : Bacterial regulatory protein, Fis family
  • pfam00158: Sigma54_activat : Sigma-54 interaction domain
Protein Accession
  • EEG54308: transcriptional regulator, Fis family [ [[Clostridium asparagiforme] DSM 15981]
  • EGW77530: propionate catabolism operon regulatory protein [Escherichia coli 2534-86]
  • P77743: RecName: Full=Propionate catabolism operon regulatory protein
  • EPC29060: sigma-54 dependent transcriptional regulator [Lactobacillus paracasei subsp. paracasei Lpp46]
  • KJE33142: bacterial regulatory, Fis family protein [Bacillus licheniformis]
Publications
  • PMID 22505679: Regulation and evolution of malonate and propionate catabolism in proteobacteria.
Gene IDs
Conserved domains in this architecture
AccessionShort nameTitle
cl26036ObsoleteThis domain/cluster is obsolete
pfam06506PrpR_NPropionate catabolism activator

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