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4WUY:
Crystal Structure Of Protein Lysine Methyltransferase Smyd2 In Complex With Lly-507, A Cell-active, Potent And Selective Inhibitor
PDB ID:
4WUY
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MMDB ID:
128465
PDB Deposition Date:
2014/11/4
Updated in MMDB:
2015/06
Experimental Method:
x-ray diffraction
Resolution:
1.63 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4WUY: monomeric; determined by author and by software (PISA)
Molecular Components in 4WUY
Label
Count
Molecule
Protein (1 molecule)
A
1
N-lysine Methyltransferase Smyd2
(Gene symbol:
SMYD2
)
Chemicals and Non-standard biopolymers (9 molecules)
1
1
5-Cyano-2'-{4-[2-(3-Methyl-1h-Indol-1-Yl)ethyl]piperazin-1-Yl}-N-[3-(Pyrrolidin-1-Yl)propyl]biphenyl-3-Carboxamide
2
1
S-Adenosyl-L-Homocysteine
3
3
Glycerol
4
4
Zinc Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303