4CSV: Tyrosine kinase AS - a common ancestor of Src and Abl bound to Gleevec

PDB ID: 4CSVDownload
MMDB ID: 127397
PDB Deposition Date: 2014/3/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 4CSV: monomeric; determined by software (PISA)
Molecular Components in 4CSV
Label Count Molecule
Protein (1 molecule)
1
Src-abl Tyrosine Kinase Ancestor
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303