3DHD: Crystal structure of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate

PDB ID: 3DHDDownload
MMDB ID: 76024
PDB Deposition Date: 2008/6/17
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3DHD: dimeric; determined by author and by software (PISA)
Molecular Components in 3DHD
Label Count Molecule
Proteins (2 molecules)
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol: NAMPT)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATEBETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
3
2
PYROPHOSPHATE 2-PYROPHOSPHATE 2-
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303