7OCB: Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B

PDB ID: 7OCBDownload
MMDB ID: 214999
PDB Deposition Date: 2021/4/26
Updated in MMDB: 2022/05
Experimental Method:
x-ray diffraction
Resolution: 1.42  Å
Source Organism:
Similar Structures:
Biological Unit for 7OCB: monomeric; determined by author and by software (PISA)
Molecular Components in 7OCB
Label Count Molecule
Protein (1 molecule)
1
Spindlin-1
(Gene symbol: SPIN1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine
2
1
PHOSPHATE IONPHOSPHATE ION
3
2
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
4
1
CHLORIDE IONCHLORIDE ION
5
1
GLYCINEGLYCINE
6
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303