6AN8: STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.0

PDB ID: 6AN8Download
MMDB ID: 165638
PDB Deposition Date: 2017/8/12
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.596  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6AN8: tetrameric; determined by author and by software (PISA)
Molecular Components in 6AN8
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase P66 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
Nucleotides(2 molecules)
1
DNA Template (5'- D(*ap*tp*gp*ap*ap*cp*gp*gp*cp*gp*cp*cp*cp*gp*ap*ap*cp*ap*gp*gp*gp*ap*cp*tp*gp*tp*g)-3')
Molecule annotation
1
DNA Primer (5'- D(*ap*cp*ap*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*gp*cp*gp*cp*cp*gp)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE
3
7
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303