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5TI6:
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 8841881
PDB ID:
5TI6
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MMDB ID:
153463
PDB Deposition Date:
2016/10/1
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
1.704 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5TI6: monomeric; determined by author
Molecular Components in 5TI6
Label
Count
Molecule
Protein (1 molecule)
A
1
Bromodomain-containing Protein 4
(Gene symbol:
BRD4
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2,6-difluoro-N-[3-(2-oxopyrrolidin-1-yl)phenyl]benzene-1-sulfonamide
2
3
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303