2G27: Ketopiperazine-Based Renin Inhibitors: Optimization Of The "c" Ring

PDB ID: 2G27Download
MMDB ID: 39933
PDB Deposition Date: 2006/2/15
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2G27: monomeric; determined by author and by software (PISA)
Molecular Components in 2G27
Label Count Molecule
Protein (1 molecule)
1
Renin
(Gene symbol: REN)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
Methyl (6-{[(2r)-1-(4-{3-[(2-Methoxybenzyl)oxy]propoxy}phenyl)-6-Oxopiperazin-2-Yl]methoxy}-1h-Indol-1-Yl)acetateMethyl (6-{[(2r)-1-(4-{3-[(2-Methoxybenzyl)oxy]propoxy}phenyl)-6-Oxopiperazin-2-Yl]methoxy}-1h-Indol-1-Yl)acetate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303