|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
441-558 |
4.45e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 441 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 517
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553116 518 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 558
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
571-683 |
5.41e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 5.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 571 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 645
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 646 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 683
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
192-314 |
1.06e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.45 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 192 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 264
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553116 265 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 314
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
322-435 |
1.92e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 322 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 397
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 398 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 435
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
820-886 |
6.13e-07 |
|
von Willebrand factor (vWF) type C domain;
:
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.13e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553116 820 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 886
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
73-147 |
2.57e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 45.49 E-value: 2.57e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553116 73 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 147
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
908-968 |
3.11e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 39.72 E-value: 3.11e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553116 908 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 968
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
742-799 |
2.79e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 37.02 E-value: 2.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 742 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 799
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
441-558 |
4.45e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 441 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 517
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553116 518 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 558
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
571-683 |
5.41e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 5.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 571 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 645
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 646 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 683
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
571-682 |
2.20e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.59 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 571 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 642
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 755553116 643 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 682
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
192-314 |
1.06e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.45 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 192 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 264
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553116 265 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 314
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
322-435 |
1.92e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 322 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 397
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 398 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 435
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
443-556 |
4.45e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 63.65 E-value: 4.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 443 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 506
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 755553116 507 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 556
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
820-886 |
6.13e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.13e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553116 820 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 886
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
73-147 |
2.57e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.49 E-value: 2.57e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553116 73 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 147
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
908-968 |
3.11e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.72 E-value: 3.11e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553116 908 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 968
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
742-799 |
2.79e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.02 E-value: 2.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 742 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 799
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
441-558 |
4.45e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 441 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 517
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553116 518 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 558
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
571-683 |
5.41e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 5.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 571 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 645
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 646 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 683
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
571-682 |
2.20e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.59 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 571 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 642
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 755553116 643 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 682
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
192-314 |
1.06e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.45 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 192 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 264
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553116 265 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 314
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
322-435 |
1.92e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 322 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 397
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553116 398 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 435
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
443-556 |
4.45e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 63.65 E-value: 4.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 443 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 506
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 755553116 507 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 556
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
820-886 |
6.13e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.13e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553116 820 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 886
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
73-147 |
2.57e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.49 E-value: 2.57e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553116 73 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 147
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
908-968 |
3.11e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.72 E-value: 3.11e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553116 908 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 968
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| Amnionless |
pfam14828 |
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ... |
74-147 |
9.99e-04 |
|
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.
Pssm-ID: 464340 Cd Length: 449 Bit Score: 42.76 E-value: 9.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 74 SFGGKVYALDETWHPDLGEPFGVM----------------RCVLCAC---EAPQWArrgrgpgrvsCKNIKPQCPTLACR 134
Cdd:pfam14828 153 SLLGQTFTSDEDFAEFLSSRLGQLqfhgagalrvgpeacsDPSGCGCgndENLERI----------CANVLQRCPPPHCL 222
|
90
....*....|...
gi 755553116 135 QPRQLPGHCCQTC 147
Cdd:pfam14828 223 SPLRPEGHCCDVC 235
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
742-799 |
2.79e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.02 E-value: 2.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553116 742 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 799
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
