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Conserved domains on  [gi|504935473|ref|WP_015122575|]
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tetratricopeptide repeat protein [Rivularia sp. PCC 7116]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 35-140 8.01e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 8.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  35 NLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                         90       100
                 ....*....|....*....|....*.
gi 504935473 115 EKQSEAIGYLQKAKEvlqkRQPQKAE 140
Cdd:COG3914  160 GRLEEAIAALRRALE----LDPDNAE 181
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 35-140 8.01e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 8.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  35 NLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                         90       100
                 ....*....|....*....|....*.
gi 504935473 115 EKQSEAIGYLQKAKEvlqkRQPQKAE 140
Cdd:COG3914  160 GRLEEAIAALRRALE----LDPDNAE 181
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 36-126 7.51e-09

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 50.74  E-value: 7.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   36 LFQKGLDLYQQKDYENAEAVFRQVT-----SINVSNdvVRLLLGDSLLKQGKVEAAIEKYKEVIER---APKKADAYLRL 107
Cdd:TIGR02795   3 YYDAALLVLKAGDYADAIQAFQAFLkkypkSTYAPN--AHYWLGEAYYAQGDYADAAKAFLAVVKKypkSPKAPDALLKL 80

                          90
                  ....*....|....*....
gi 504935473  108 SRIYMQQEKQSEAIGYLQK 126
Cdd:TIGR02795  81 GMSLQELGDKEKAKATLQQ 99
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 22-130 7.63e-07

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 46.60  E-value: 7.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  22 LLIYFAVKTLRTSN---LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAP 98
Cdd:NF040959  91 IKVLEKVLSLAPDHvkaAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRLGLALDGLGQYDKAIEAFQKALELDP 170

                         90       100       110
                 ....*....|....*....|....*....|..
gi 504935473  99 KKADAYLRLSRIYMQQEKQSEAIGYLQKAKEV 130
Cdd:NF040959 171 NEIKYHQAIGFMYVQKGDHETAAEHFKKAMEL 202
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 71-129 1.95e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 43.09  E-value: 1.95e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504935473   71 LLLGDSLLKQGKVEAAIEKYKEVIER---APKKADAYLRLSRIYMQQEKQSEAIGYLQKAKE 129
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARfpeSPDAAAALLLLGLAALRQGRLAEAAAAYRAALR 62
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 41-149 1.25e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 43.64  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  41 LDLYQQ-KDYENAEAVFRQVTSINVSNDVVRLL-----LGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:PRK11788 148 LEIYQQeKDWQKAIDVAERLEKLGGDSLRVEIAhfyceLAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQ 227

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 504935473 115 EKQSEAIGYLQKAKEvlqkrqpQKAEEVSQLLEKL 149
Cdd:PRK11788 228 GDYAAAIEALERVEE-------QDPEYLSEVLPKL 255
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 36-151 4.31e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 4.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKK-ADAYLrlsriYMQQ 114
Cdd:cd24142    3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYL-----YLGQ 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 504935473 115 -EKQSEAIGYLQKAKEVLQ-------KRQPQKAEEVSQLLEKLNS 151
Cdd:cd24142   78 lSGGEEALQYYEKGIEILEeelqalqAASAEAEEEAEELKRKLSS 122
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 35-140 8.01e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 8.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  35 NLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                         90       100
                 ....*....|....*....|....*.
gi 504935473 115 EKQSEAIGYLQKAKEvlqkRQPQKAE 140
Cdd:COG3914  160 GRLEEAIAALRRALE----LDPDNAE 181
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 36-146 1.31e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.72  E-value: 1.31e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG3914  115 LFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLG 194

                         90       100       110
                 ....*....|....*....|....*....|.
gi 504935473 116 KQSEAIGYLQKAKEvlqkRQPQKAEEVSQLL 146
Cdd:COG3914  195 RLEEAIAAYRRALE----LDPDNADAHSNLL 221
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 36-150 9.03e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.75  E-value: 9.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 504935473 116 KQSEAIGYLQKAKEvLQKRQPQKAEEVSQLLEKLN 150
Cdd:COG4783   87 DYDEALALLEKALK-LDPEHPEAYLRLARAYRALG 120
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 36-129 1.69e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 1.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         90
                 ....*....|....
gi 504935473 116 KQSEAIGYLQKAKE 129
Cdd:COG4783  121 RPDEAIAALEKALE 134
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-127 3.65e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 64.64  E-value: 3.65e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                         90
                 ....*....|..
gi 504935473 116 KQSEAIGYLQKA 127
Cdd:COG0457   91 RYEEALEDYDKA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 36-129 4.33e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.37  E-value: 4.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG2956  147 YCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLG 226

                         90
                 ....*....|....
gi 504935473 116 KQSEAIGYLQKAKE 129
Cdd:COG2956  227 DPEEALELLRKALE 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 37-150 4.88e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.37  E-value: 4.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  37 FQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEK 116
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 504935473 117 QSEAIGYLQKAKEV---------------LQKRQPQKAEEVSQLLEKLN 150
Cdd:COG2956   92 LDRAEELLEKLLELdpddaealrllaeiyEQEGDWEKAIEVLERLLKLG 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 32-127 6.09e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 6.09e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  32 RTSNLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIY 111
Cdd:COG2956   75 RAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELY 154

                         90
                 ....*....|....*.
gi 504935473 112 MQQEKQSEAIGYLQKA 127
Cdd:COG2956  155 LEQGDYDEAIEALEKA 170
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 43-149 7.16e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 7.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIG 122
Cdd:COG4235   27 YLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIA 106

                         90       100
                 ....*....|....*....|....*..
gi 504935473 123 YLQKAKEVLQKRQPqkAEEVSQLLEKL 149
Cdd:COG4235  107 AWQKLLALLPADAP--ARLLEASIAEA 131
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-127 1.30e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG0457   45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                         90
                 ....*....|..
gi 504935473 116 KQSEAIGYLQKA 127
Cdd:COG0457  125 RYDEAIEAYERA 136
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
43-127 2.02e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.41  E-value: 2.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEkYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIG 122
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                 ....*
gi 504935473 123 YLQKA 127
Cdd:COG3063   81 YLERA 85
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-129 1.50e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 1.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                         90
                 ....*....|....
gi 504935473 116 KQSEAIGYLQKAKE 129
Cdd:COG0457  159 RYEEALELLEKLEA 172
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
34-129 2.74e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.16  E-value: 2.74e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  34 SNLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQ 113
Cdd:COG4785   74 QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYY 153

                         90
                 ....*....|....*.
gi 504935473 114 QEKQSEAIGYLQKAKE 129
Cdd:COG4785  154 LGRYELAIADLEKALE 169
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 41-149 1.06e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 55.38  E-value: 1.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  41 LDLYQQKDYENAEAVFRQVTSINVSNDV---VRLLLGDSLLKQGKVEAAIEKYKEVIERAP---KKADAYLRLSRIYMQQ 114
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPdspKAPDALLKLGLSYLEL 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 504935473 115 EKQSEAIGYLQKAKEvlQKRQPQKAEEVSQLLEKL 149
Cdd:COG1729   81 GDYDKARATLEELIK--KYPDSEAAKEARARLARL 113
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 43-127 4.38e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 4.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIG 122
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 ....*
gi 504935473 123 YLQKA 127
Cdd:COG5010  144 ALQRA 148
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 40-132 2.87e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.23  E-value: 2.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  40 GLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSE 119
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV 232

                         90
                 ....*....|...
gi 504935473 120 AIGYLQKAKEVLQ 132
Cdd:COG3914  233 YDRFEELLAALAR 245
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 36-126 7.51e-09

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 50.74  E-value: 7.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   36 LFQKGLDLYQQKDYENAEAVFRQVT-----SINVSNdvVRLLLGDSLLKQGKVEAAIEKYKEVIER---APKKADAYLRL 107
Cdd:TIGR02795   3 YYDAALLVLKAGDYADAIQAFQAFLkkypkSTYAPN--AHYWLGEAYYAQGDYADAAKAFLAVVKKypkSPKAPDALLKL 80

                          90
                  ....*....|....*....
gi 504935473  108 SRIYMQQEKQSEAIGYLQK 126
Cdd:TIGR02795  81 GMSLQELGDKEKAKATLQQ 99
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 52-127 5.08e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 5.08e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504935473  52 AEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERA 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 40-130 1.17e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   40 GLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSE 119
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                          90
                  ....*....|.
gi 504935473  120 AIGYLQKAKEV 130
Cdd:TIGR02917 382 AAEYLAKATEL 392
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 22-130 7.63e-07

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 46.60  E-value: 7.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  22 LLIYFAVKTLRTSN---LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAP 98
Cdd:NF040959  91 IKVLEKVLSLAPDHvkaAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRLGLALDGLGQYDKAIEAFQKALELDP 170

                         90       100       110
                 ....*....|....*....|....*....|..
gi 504935473  99 KKADAYLRLSRIYMQQEKQSEAIGYLQKAKEV 130
Cdd:NF040959 171 NEIKYHQAIGFMYVQKGDHETAAEHFKKAMEL 202
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 71-127 1.11e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 1.11e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 504935473   71 LLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:TIGR02917 605 LMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRA 661
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 69-127 1.63e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 1.63e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 504935473  69 VRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEA 64
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 13-129 1.89e-06

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 45.62  E-value: 1.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  13 AVIVLSSIFLLIYFAV---------KTLRTSNLFQKGLDLYQQKDYENAEAVFRQVTSINVSN---DVVRLLLGDSLLKQ 80
Cdd:COG2976   24 AIIVGVVLGLAAVFGWrywqsyqesQAEEASALYEQLLEALAAGDAAAAAAAAEKLIDDYGGTayaALAALLLAKAAVDA 103

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 504935473  81 GKVEAAIEKYKEVIERAPK---KADAYLRLSRIYMQQEKQSEAIGYLQKAKE 129
Cdd:COG2976  104 GDLDKAAAQLQWVLDNAKDpalKALARLRLARVLLAQKKYDEALATLDAVKP 155
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 71-129 1.95e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 43.09  E-value: 1.95e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504935473   71 LLLGDSLLKQGKVEAAIEKYKEVIER---APKKADAYLRLSRIYMQQEKQSEAIGYLQKAKE 129
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARfpeSPDAAAALLLLGLAALRQGRLAEAAAAYRAALR 62
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 37-101 2.48e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 42.71  E-value: 2.48e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504935473   37 FQKGLDLYQQKDYENAEAVFRQVTSINVSNDV---VRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKA 101
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 36-127 2.55e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.75  E-value: 2.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG3914   47 LLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG 126

                         90
                 ....*....|..
gi 504935473 116 KQSEAIGYLQKA 127
Cdd:COG3914  127 RLEEALAALRRA 138
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 47-129 2.59e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 2.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   47 KDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQK 126
Cdd:TIGR02917 479 GDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEK 558


                  ...
gi 504935473  127 AKE 129
Cdd:TIGR02917 559 AAE 561
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
61-127 4.00e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 4.00e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504935473  61 SINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQA 68
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 36-110 4.88e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.06  E-value: 4.88e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVV---RLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRI 110
Cdd:COG1729   33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKEARARL 110
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 36-110 5.05e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 5.05e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRI 110
Cdd:COG4235   54 LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 41-149 1.25e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 43.64  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  41 LDLYQQ-KDYENAEAVFRQVTSINVSNDVVRLL-----LGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:PRK11788 148 LEIYQQeKDWQKAIDVAERLEKLGGDSLRVEIAhfyceLAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQ 227

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 504935473 115 EKQSEAIGYLQKAKEvlqkrqpQKAEEVSQLLEKL 149
Cdd:PRK11788 228 GDYAAAIEALERVEE-------QDPEYLSEVLPKL 255
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 36-150 1.59e-05

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 42.95  E-value: 1.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDV---VRLLLGDSLLKQGKVEAAIEKYKEVIE---RAPKKADAYLRLSR 109
Cdd:COG4105   35 LYEEAKEALEKGDYEKAIKLFEELEPRYPGSPYaeqAQLMLAYAYYKQGDYEEAIAAADRFIKlypNSPNADYAYYLRGL 114

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 504935473 110 IYMQQEKQSE-AIGYLQKAKEVLQ---KRQPQ--KAEEVSQLLEKLN 150
Cdd:COG4105  115 SYYEQSPDSDrDQTSTRKAIEAFQeliNRYPDseYAEDAKKRIDELR 161
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 34-129 2.55e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 2.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   34 SNLFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQ 113
Cdd:TIGR02917 737 QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLE 816

                          90
                  ....*....|....*.
gi 504935473  114 QeKQSEAIGYLQKAKE 129
Cdd:TIGR02917 817 L-KDPRALEYAERALK 831
TPR_11 pfam13414
TPR repeat;
74-114 3.11e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.99  E-value: 3.11e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 504935473   74 GDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQ 114
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 46-138 4.82e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 4.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   46 QKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAigylQ 125
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA----E 247

                          90
                  ....*....|...
gi 504935473  126 KAKEVLQKRQPQK 138
Cdd:TIGR02917 248 KHADALLKKAPNS 260
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 39-127 7.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 7.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   39 KGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQS 118
Cdd:TIGR02917 199 KGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYE 278


                  ....*....
gi 504935473  119 EAIGYLQKA 127
Cdd:TIGR02917 279 DARETLQDA 287
TPR_19 pfam14559
Tetratricopeptide repeat;
80-149 1.10e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.33  E-value: 1.10e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504935473   80 QGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQekqseaiGYLQKAKEVLQK--RQPQKAEEVSQLLEKL 149
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLAL-------GRLDEAEALLAAlpAADPDDPRYAALLAKL 65
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-150 1.88e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 1.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:COG0457  113 LYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAA 192

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 504935473 116 KQSEAIGYLQKAKEVLQKRQPQKAEEVSQLLEKLN 150
Cdd:COG0457  193 AEVLLALLLALEQALRKKLAILTLAALAELLLLAL 227
TPR_12 pfam13424
Tetratricopeptide repeat;
71-133 2.22e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.22e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504935473   71 LLLGDSLLKQGKVEAAIEKYKEVIERA--------PKKADAYLRLSRIYMQQEKQSEAIGYLQKAKEVLQK 133
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
36-133 2.30e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.51  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLsriYMQQE 115
Cdd:COG4785  110 YNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWL---YLAER 186

                         90
                 ....*....|....*...
gi 504935473 116 KQSEaigylQKAKEVLQK 133
Cdd:COG4785  187 KLDP-----EKALALLLE 199
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 40-139 2.38e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 2.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   40 GLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSE 119
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDK 449

                          90       100
                  ....*....|....*....|
gi 504935473  120 AIgylqKAKEVLQKRQPQKA 139
Cdd:TIGR02917 450 AL----AAAKKLEKKQPDNA 465
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 39-141 2.49e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 2.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   39 KGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQS 118
Cdd:TIGR02917 267 KALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVD 346

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 504935473  119 EAIGYLQKA---------------KEVLQKRQPQKAEE 141
Cdd:TIGR02917 347 EAIATLSPAlgldpddpaalsllgEAYLALGDFEKAAE 384
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
36-99 2.73e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 2.73e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504935473  36 LFQKGLDLYQQKDYENAEAvFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPK 99
Cdd:COG3063   29 LNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 77-129 2.98e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 2.98e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 504935473  77 LLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKAKE 129
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 36-99 3.66e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 3.66e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPK 99
Cdd:COG4783   75 RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 36-98 4.26e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 4.26e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAP 98
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 36-151 4.31e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 4.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKK-ADAYLrlsriYMQQ 114
Cdd:cd24142    3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYL-----YLGQ 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 504935473 115 -EKQSEAIGYLQKAKEVLQ-------KRQPQKAEEVSQLLEKLNS 151
Cdd:cd24142   78 lSGGEEALQYYEKGIEILEeelqalqAASAEAEEEAEELKRKLSS 122
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 85-127 4.38e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 4.38e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 504935473  85 AAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKA 43
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 36-147 8.98e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.53  E-value: 8.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   36 LFQKGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQE 115
Cdd:PRK11447  354 LIQQGDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQS 433

                          90       100       110
                  ....*....|....*....|....*....|..
gi 504935473  116 KQsEAIGYLQKakevLQKRQPQKAEEVSQLLE 147
Cdd:PRK11447  434 PE-KALAFIAS----LSASQRRSIDDIERSLQ 460
TPR_19 pfam14559
Tetratricopeptide repeat;
46-110 1.08e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.64  E-value: 1.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504935473   46 QKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRI 110
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 69-127 1.29e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 37.70  E-value: 1.29e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 504935473   69 VRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKA 127
Cdd:TIGR02521  33 IRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRA 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 39-145 1.46e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 37.76  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   39 KGLDLYQQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQS 118
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTE 686

                          90       100
                  ....*....|....*....|....*..
gi 504935473  119 EAIGYLQKakevLQKRQPQKAEEVSQL 145
Cdd:TIGR02917 687 SAKKIAKS----LQKQHPKAALGFELE 709
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 44-149 1.74e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 37.20  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  44 YQQKDYENAEAVFRQVTSIN-VSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIG 122
Cdd:COG3071   61 QALGDYERRDEYLAQALELApEAELAVLLTRAELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLE 140

                         90       100
                 ....*....|....*....|....*..
gi 504935473 123 YLQKakevLQKRQPQKAEEVSQLLEKL 149
Cdd:COG3071  141 LLPA----LRKHKALSAEEAQALERRA 163
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 45-127 2.44e-03

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 34.92  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   45 QQKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLrLSRIYMQQEKQSEAIGYL 124
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYL-FAQCLLKLKKYDEALDAL 79


                  ...
gi 504935473  125 QKA 127
Cdd:pfam12895  80 GKA 82
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
43-120 2.55e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 36.78  E-value: 2.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSINVSNDVVR--LLLGDSLLKQGKVEAAIEKYKEVIERAPkKADAYLRLSRIYMQQEKQSEA 120
Cdd:COG4700  134 LFELGRYAEALETLEKLIAKNPDFKSSDahLLYARALEALGDLEAAEAELEALARRYS-GPEARYRYAKFLARQGRTAEA 212
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 70-145 2.78e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.99  E-value: 2.78e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504935473   70 RLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQKakevLQKRQPQKAEEVSQL 145
Cdd:TIGR02917 570 ALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKK----LLALQPDSALALLLL 641
TPR1 COG4649
TPR-like repeat domain [Function unknown];
37-110 3.96e-03

TPR-like repeat domain [Function unknown];


Pssm-ID: 443687 [Multi-domain]  Cd Length: 222  Bit Score: 36.00  E-value: 3.96e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504935473  37 FQKGLDLYQQKDYENAEAVFRQVTSINVSN--DVVRLLLGDSLLKQGKVEAAIEKYKEVIerAPKKADAYLR-LSRI 110
Cdd:COG4649   63 YLAALELAEAGDAAEAAAALAALAADGPGGyaALARLRAAALLAQAGDTAAAVAAYDAVA--ADASAPPLLRdLARL 137
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 43-150 5.16e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 36.04  E-value: 5.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSINVSNDVVRLLlgdSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIG 122
Cdd:COG3071  203 LIALGDHDEAERLLREALKRQWDPRLVRLY---GRLQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKARE 279

                         90       100
                 ....*....|....*....|....*...
gi 504935473 123 YLQKAkeVLQKRQPQKAEEVSQLLEKLN 150
Cdd:COG3071  280 YLEAA--LALRPSAEAYAELARLLEQLG 305
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 43-151 5.79e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 35.60  E-value: 5.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473  43 LYQQKDYENAEAVFRQVTSiNVSND----VVRLLLGDSLLKQGKVEAAIEKYKEVIErAPKKADAYLRLSRIYMQQEKQS 118
Cdd:COG2976  100 AVDAGDLDKAAAQLQWVLD-NAKDPalkaLARLRLARVLLAQKKYDEALATLDAVKP-EAFAALYAELRGDILLAQGDKA 177

                         90       100       110
                 ....*....|....*....|....*....|....
gi 504935473 119 EAIGYLQKAKEVLQKRQPQKaeevsQLLE-KLNS 151
Cdd:COG2976  178 EARAAYQKALAALPEDAPLR-----QLLQmKLDD 206
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 46-147 6.44e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 35.83  E-value: 6.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   46 QKDYENAEAvfrqvtsinvsndvvRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQ 125
Cdd:TIGR02917  50 QKDPNDAEA---------------RFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELP 114

                          90       100
                  ....*....|....*....|..
gi 504935473  126 KAKevlqkrqPQKAEEVSQLLE 147
Cdd:TIGR02917 115 GKT-------LLDDEGAAELLA 129
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 46-127 6.88e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 35.83  E-value: 6.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   46 QKDYENAEAVFRQVTSINVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAYLRLSRIYMQQEKQSEAIGYLQ 125
Cdd:TIGR02917 648 MKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYR 727


                  ..
gi 504935473  126 KA 127
Cdd:TIGR02917 728 KA 729
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 45-150 9.33e-03

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 35.34  E-value: 9.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504935473   45 QQKDYENAEAVFRQVTSI-NVSNDVVRLLLGDSLLKQGKVEAAIEKYKEVIERAPKKADAyLRLSRIYMQQEKQSEAigy 123
Cdd:TIGR00540 111 QMGDEERRDRYLAEAAELaPNSELAVLLTRAELLLDQRDYEAALAALDSLQAQAPRHTAV-LRLALRAYQRSGNWDA--- 186

                          90       100
                  ....*....|....*....|....*..
gi 504935473  124 LQKAKEVLQKRQPQKAEEVSQLLEKLN 150
Cdd:TIGR00540 187 LLKLLPALRKAKALSPEEAARLEQQAY 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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