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Conserved domains on  [gi|18405298|ref|NP_564684|]
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Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
155-324 6.57e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 100.62  E-value: 6.57e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 155 WQPLPPVPreysEAVGFGCAVLSGCHLYLFGGKDPLRGSmRRVIFYNARTNKWHRAPDM-LRKRHFFGCCVINNCLYVAG 233
Cdd:COG3055   3 WSSLPDLP----TPRSEAAAALLDGKVYVAGGLSGGSAS-NSFEVYDPATNTWSELAPLpGPPRHHAAAVAQDGKLYVFG 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 234 G--ECEGIQRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKG--LGSHQLVMSEAYDPEVNSWSPVSD--- 306
Cdd:COG3055  78 GftGANPSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGgwDDGGNVAWVEVYDPATGTWTQLAPlpt 157

                       170       180
                ....*....|....*....|.
gi 18405298 307 ---GMVAGwrnpcTSLNGRLY 324
Cdd:COG3055 158 prdHLAAA-----VLPDGKIL 173
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 78-122 1.11e-11

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 438923  Cd Length: 45  Bit Score: 59.12  E-value: 1.11e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 18405298  78 LLPGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFFYSQR 122
Cdd:cd22152   1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
155-324 6.57e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 100.62  E-value: 6.57e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 155 WQPLPPVPreysEAVGFGCAVLSGCHLYLFGGKDPLRGSmRRVIFYNARTNKWHRAPDM-LRKRHFFGCCVINNCLYVAG 233
Cdd:COG3055   3 WSSLPDLP----TPRSEAAAALLDGKVYVAGGLSGGSAS-NSFEVYDPATNTWSELAPLpGPPRHHAAAVAQDGKLYVFG 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 234 G--ECEGIQRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKG--LGSHQLVMSEAYDPEVNSWSPVSD--- 306
Cdd:COG3055  78 GftGANPSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGgwDDGGNVAWVEVYDPATGTWTQLAPlpt 157

                       170       180
                ....*....|....*....|.
gi 18405298 307 ---GMVAGwrnpcTSLNGRLY 324
Cdd:COG3055 158 prdHLAAA-----VLPDGKIL 173
PHA03098 PHA03098
kelch-like protein; Provisional
 171-356 5.63e-13

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 70.57  E-value: 5.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  171 FGCAVLSGChLYLFGGKDPLRGSMRRVIFYNARTNKWHRAPDMLRKRHFFGCCVINNCLYVAGGECEGI----------- 239
Cdd:PHA03098 288 FGSVVLNNV-IYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSIslntveswkpg 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  240 -----------------------------------QRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKGLG 284
Cdd:PHA03098 367 eskwreepplifprynpcvvnvnnliyviggisknDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGI 446

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  285 SH-----QLVMSEAYDPEVNSWSPVSDGMVAGWRNPCTSLNGRLY--GLDCRDGC--KLRVFDESTDSWNKFMDSKAHLG 355
Cdd:PHA03098 447 SYidnikVYNIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYvvGGDKYEYYinEIEVYDDKTNTWTLFCKFPKVIG 526


                 .
gi 18405298  356 N 356
Cdd:PHA03098 527 S 527
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 78-122 1.11e-11

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438923  Cd Length: 45  Bit Score: 59.12  E-value: 1.11e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 18405298  78 LLPGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFFYSQR 122
Cdd:cd22152   1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 217-263 4.95e-10

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 54.54  E-value: 4.95e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 18405298   217 RHFFGCCVINNCLYVAGGECEgiQRTLRSAEVYDPNKNRWSFIADMS 263
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDG--NQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
180-227 6.70e-07

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 45.63  E-value: 6.70e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 18405298    180 HLYLFGGKDPlRGSMRRVIFYNARTNKWHRAPDMLRKRHFFGCCVINN 227
Cdd:smart00612   1 KIYVVGGFDG-GQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 79-119 1.04e-03

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 36.75  E-value: 1.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 18405298    79 LPGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFFY 119
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLKLW 41
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
155-324 6.57e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 100.62  E-value: 6.57e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 155 WQPLPPVPreysEAVGFGCAVLSGCHLYLFGGKDPLRGSmRRVIFYNARTNKWHRAPDM-LRKRHFFGCCVINNCLYVAG 233
Cdd:COG3055   3 WSSLPDLP----TPRSEAAAALLDGKVYVAGGLSGGSAS-NSFEVYDPATNTWSELAPLpGPPRHHAAAVAQDGKLYVFG 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 234 G--ECEGIQRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKG--LGSHQLVMSEAYDPEVNSWSPVSD--- 306
Cdd:COG3055  78 GftGANPSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGgwDDGGNVAWVEVYDPATGTWTQLAPlpt 157

                       170       180
                ....*....|....*....|.
gi 18405298 307 ---GMVAGwrnpcTSLNGRLY 324
Cdd:COG3055 158 prdHLAAA-----VLPDGKIL 173
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
132-344 2.00e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 93.30  E-value: 2.00e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 132 VYVFKRDRDGKISwNTF---DPISQLWQPLPPVPREyseAVGFGCAVLSGCHLYLFGG---KDPLRGSMRRVIFYNARTN 205
Cdd:COG3055  25 VYVAGGLSGGSAS-NSFevyDPATNTWSELAPLPGP---PRHHAAAVAQDGKLYVFGGftgANPSSTPLNDVYVYDPATN 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 206 KWHRAPDMLRKRHFFGCCVINNCLYVAGGECEGiqRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVV-YDKKWFLKGlG 284
Cdd:COG3055 101 TWTKLAPMPTPRGGATALLLDGKIYVVGGWDDG--GNVAWVEVYDPATGTWTQLAPLPTPRDHLAAAVlPDGKILVIG-G 177

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18405298 285 SHqlvmseaYDPEVNSWSPVSDGMVAGWRNPCTSLNGRLYGLDCRDG--CKLRVFDESTDSW 344
Cdd:COG3055 178 RN-------GSGFSNTWTTLAPLPTARAGHAAAVLGGKILVFGGESGfsDEVEAYDPATNTW 232
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
207-344 1.89e-16

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 79.04  E-value: 1.89e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 207 WHRAPDMLRKRHFFGCCVINNCLYVAGGECEGiqRTLRSAEVYDPNKNRWSFIADMST-AMVPLIGVVYDKKWFL----- 280
Cdd:COG3055   3 WSSLPDLPTPRSEAAAALLDGKVYVAGGLSGG--SASNSFEVYDPATNTWSELAPLPGpPRHHAAAVAQDGKLYVfggft 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18405298 281 KGLGSHQLVMS-EAYDPEVNSWSPVSDGMVAGWRNPCTSLNGRLYGLDCRDGCKLR----VFDESTDSW 344
Cdd:COG3055  81 GANPSSTPLNDvYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVawveVYDPATGTW 149
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
132-280 1.91e-16

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 79.04  E-value: 1.91e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298 132 VYVFK-RDRDGKISWN-TFDPISQLWQPLPPVPREYSeavGFGCAVLSGCHLYLFGGKDplrgsmrrvifYNARTNKWHR 209
Cdd:COG3055 124 IYVVGgWDDGGNVAWVeVYDPATGTWTQLAPLPTPRD---HLAAAVLPDGKILVIGGRN-----------GSGFSNTWTT 189

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18405298 210 APDMLRKRHFFGCCVINNCLYVAGGEcegiQRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFL 280
Cdd:COG3055 190 LAPLPTARAGHAAAVLGGKILVFGGE----SGFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYV 256
PHA03098 PHA03098
kelch-like protein; Provisional
 171-356 5.63e-13

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 70.57  E-value: 5.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  171 FGCAVLSGChLYLFGGKDPLRGSMRRVIFYNARTNKWHRAPDMLRKRHFFGCCVINNCLYVAGGECEGI----------- 239
Cdd:PHA03098 288 FGSVVLNNV-IYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSIslntveswkpg 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  240 -----------------------------------QRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKGLG 284
Cdd:PHA03098 367 eskwreepplifprynpcvvnvnnliyviggisknDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGI 446

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  285 SH-----QLVMSEAYDPEVNSWSPVSDGMVAGWRNPCTSLNGRLY--GLDCRDGC--KLRVFDESTDSWNKFMDSKAHLG 355
Cdd:PHA03098 447 SYidnikVYNIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYvvGGDKYEYYinEIEVYDDKTNTWTLFCKFPKVIG 526


                 .
gi 18405298  356 N 356
Cdd:PHA03098 527 S 527
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 78-122 1.11e-11

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438923  Cd Length: 45  Bit Score: 59.12  E-value: 1.11e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 18405298  78 LLPGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFFYSQR 122
Cdd:cd22152   1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 217-263 4.95e-10

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 54.54  E-value: 4.95e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 18405298   217 RHFFGCCVINNCLYVAGGECEgiQRTLRSAEVYDPNKNRWSFIADMS 263
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDG--NQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
180-227 6.70e-07

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 45.63  E-value: 6.70e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 18405298    180 HLYLFGGKDPlRGSMRRVIFYNARTNKWHRAPDMLRKRHFFGCCVINN 227
Cdd:smart00612   1 KIYVVGGFDG-GQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch smart00612
Kelch domain;
228-276 9.72e-07

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 45.24  E-value: 9.72e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 18405298    228 CLYVAGGeCEGIQRtLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDK 276
Cdd:smart00612   1 KIYVVGG-FDGGQR-LKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
F-box_AtFBW1-like cd22157
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ...
 80-118 1.27e-05

F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438928  Cd Length: 39  Bit Score: 42.06  E-value: 1.27e-05
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 18405298  80 PGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFF 118
Cdd:cd22157   1 SSLPDDLVEEILSRLPAKSLLRFRCVCKQWNSLISSPSF 39
PHA02790 PHA02790
Kelch-like protein; Provisional
 151-306 4.29e-05

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 45.80  E-value: 4.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  151 ISQLWQPLPPV--PREYSEAVGfgcavlSGCHLYLFGGKdPLRGSMRRviFYNARTNkWHRAPDMLRKRHFFGCCVINNC 228
Cdd:PHA02790 295 ISNNWIPIPPMnsPRLYASGVP------ANNKLYVVGGL-PNPTSVER--WFHGDAA-WVNMPSLLKPRCNPAVASINNV 364

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18405298  229 LYVAGGECEgiqrTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKGLGshqlvmSEAYDPEVNSWSPVSD 306
Cdd:PHA02790 365 IYVIGGHSE----TDTTTEYLLPNHDQWQFGPSTYYPHYKSCALVFGRRLFLVGRN------AEFYCESSNTWTLIDD 432
Kelch_6 pfam13964
Kelch motif;
217-262 4.97e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 40.78  E-value: 4.97e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 18405298   217 RHFFGCCVINNCLYVAGGECEGIQRtLRSAEVYDPNKNRWSFIADM 262
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPA-LNKLEVYNPLTKSWEELPPL 46
Kelch_6 pfam13964
Kelch motif;
171-217 6.30e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 40.40  E-value: 6.30e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 18405298   171 FGCAVLSGCHLYLFGGKDPLRGSMRRVIFYNARTNKWHRAPDMLRKR 217
Cdd:pfam13964   4 FHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
PHA03098 PHA03098
kelch-like protein; Provisional
 187-357 2.93e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 43.22  E-value: 2.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  187 KDPLRGSMRRVIFYNARTNKWhrapDMLRKRHF---FGCCVINNCLYVAGGEcegIQRTLRSAEV--YDPNKNRWSFIAD 261
Cdd:PHA03098 256 HITMSIFTYNYITNYSPLSEI----NTIIDIHYvycFGSVVLNNVIYFIGGM---NKNNLSVNSVvsYDTKTKSWNKVPE 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405298  262 MSTAMVPLIGVVYDKKWFLKG--LGSHQLVMSEAYDPEVNSWSPVSDgMVAGWRNPCT-SLNGRLY---GLDCRDGCK-- 333
Cdd:PHA03098 329 LIYPRKNPGVTVFNNRIYVIGgiYNSISLNTVESWKPGESKWREEPP-LIFPRYNPCVvNVNNLIYvigGISKNDELLkt 407

                        170       180
                 ....*....|....*....|....
gi 18405298  334 LRVFDESTDSWNKFMDSKAHLGNS 357
Cdd:PHA03098 408 VECFSLNTNKWSKGSPLPISHYGG 431
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 169-213 8.99e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 36.82  E-value: 8.99e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 18405298   169 VGFGCAVLSGChLYLFGGKDPLRgSMRRVIFYNARTNKWHRAPDM 213
Cdd:pfam01344   3 SGAGVVVVGGK-IYVIGGFDGNQ-SLNSVEVYDPETNTWSKLPSM 45
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 79-119 1.04e-03

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 36.75  E-value: 1.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 18405298    79 LPGLPDDLAVACLIRVPRAEHRKLRLVCKRWYRLASGNFFY 119
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLKLW 41
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 222-262 1.35e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 36.55  E-value: 1.35e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 18405298   222 CCVINNCLYVAGGECEGIQRTLRSAEVYDPNKNRWSFIADM 262
Cdd:pfam07646   7 SSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWTEVPRL 47
Kelch_3 pfam13415
Galactose oxidase, central domain;
178-225 1.70e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 36.11  E-value: 1.70e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 18405298   178 GCHLYLFGGKDPLRGSM-RRVIFYNARTNKWHRAPDMLRKRHFFGCCVI 225
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRlNDLYVYDLDTNTWTQIGDLPPPRSGHSATYI 49
F-box_SF cd09917
F-box domain superfamily; This short domain is commonly found at the N-terminus of various ...
 82-114 9.51e-03

F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures.


Pssm-ID: 438852  Cd Length: 35  Bit Score: 33.57  E-value: 9.51e-03
                        10        20        30
                ....*....|....*....|....*....|...
gi 18405298  82 LPDDLAVACLIRVPRAEHRKLRLVCKRWYRLAS 114
Cdd:cd09917   3 LPDEILLKILSYLDPRDLLRLSLVCKRWRELAS 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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