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Conserved domains on  [gi|1772567150|ref|XP_021388296|]
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sulfotransferase 1 family member D1 [Lonchura striata domestica]

Protein Classification

sulfotransferase domain-containing protein( domain architecture ID 10464534)

sulfotransferase domain-containing protein such as mammalian sulfotransferases that utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as the sulfonate donor to catalyze the sulfate conjugation of a variety of substrates including catecholamines, phenolic drugs, neurotransmitters, heparan, and estrogen, among others

CATH:  3.40.50.300
EC:  2.8.2.-
Gene Ontology:  GO:0008146
PubMed:  9360604|31270211
SCOP:  4003933

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
230-480 1.42e-118

Sulfotransferase domain;


:

Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 348.18  E-value: 1.42e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 230 PDDLLISTYPKSGTTWLSEIMDMIYHNGDVEKCRRDAI---YNRVPFLELKV----SKSLCGVDQLENTPSPRLVKTHLP 302
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRGDFEKSEEPHLfnnHNRSPFLEWYPgdtyFDVAEGPVRLNALPSPRIIKTHLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 303 VQLLPTSFWEKDCKIIYMARNPKDVVISYYYFHQMAKIHHDPGTKAEFLENFMAGKVPYGSWYDHVRGWWEKKREKKILY 382
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVNCGSYFDHVKGWWKLRPPGNILF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 383 LFYEDMKKDPRQEVQKILQFLGKELSERTVESILHHTSFQEMKKNPAANYETMLPtlmdhSISPFLRKGISGDWKNHFTV 462
Cdd:pfam00685 161 LRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLSFENMKGNPCLNYSKLPK-----EVSPFFRKGLVGDWKNYFTP 235

                         250
                  ....*....|....*...
gi 1772567150 463 AQNERFDQHYQELMAGSD 480
Cdd:pfam00685 236 EQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
230-480 1.42e-118

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 348.18  E-value: 1.42e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 230 PDDLLISTYPKSGTTWLSEIMDMIYHNGDVEKCRRDAI---YNRVPFLELKV----SKSLCGVDQLENTPSPRLVKTHLP 302
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRGDFEKSEEPHLfnnHNRSPFLEWYPgdtyFDVAEGPVRLNALPSPRIIKTHLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 303 VQLLPTSFWEKDCKIIYMARNPKDVVISYYYFHQMAKIHHDPGTKAEFLENFMAGKVPYGSWYDHVRGWWEKKREKKILY 382
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVNCGSYFDHVKGWWKLRPPGNILF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 383 LFYEDMKKDPRQEVQKILQFLGKELSERTVESILHHTSFQEMKKNPAANYETMLPtlmdhSISPFLRKGISGDWKNHFTV 462
Cdd:pfam00685 161 LRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLSFENMKGNPCLNYSKLPK-----EVSPFFRKGLVGDWKNYFTP 235

                         250
                  ....*....|....*...
gi 1772567150 463 AQNERFDQHYQELMAGSD 480
Cdd:pfam00685 236 EQAEKFDEIYQEKMKGTG 253
PLN02164 PLN02164
sulfotransferase
 158-481 1.48e-34

sulfotransferase


Pssm-ID: 177822  Cd Length: 346  Bit Score: 132.35  E-value: 1.48e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 158 SSTTPGTVLAQVPASSEVVKATSREDSQCCV-DPLSAMEQEDAIRQE--LGSLHGIPLYKSFIEGWPQVKA-FQARPDDL 233
Cdd:PLN02164    3 SKTLNDTVTTVPSHEEAVTEPTEFEKNQKRYqDLIATLPHKKGWRPKepLIEYGGHWWLQPLLEGLLHAQEfFQARPNDF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 234 LISTYPKSGTTWLSEIMDMIyhngdVEKCRRDAIYNR---------VPFLELKVSkSLCGVDQLENTPSPrLVKTHLPVQ 304
Cdd:PLN02164   83 LVCSYPKTGTTWLKALTFAI-----ANRSRFDDSSNPllkrnphefVPYIEIDFP-FFPSVDVLKDKGNT-LFSTHIPYG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 305 LLPTSFWEKDCKIIYMARNPKDVVISYYYFHQMAKIHHDP-GTKAEFLENFMAGKVPYGSWYDHVRGWWEKKREK--KIL 381
Cdd:PLN02164  156 LLPDSVVKSGCKMVYIWRDPKDTFISMWTFLHKERSQQGPlNSLEESFDMFCRGLSVYGPYLDHVLGYWKAYQENpdRIL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 382 YLFYEDMKKDPRQEVQKILQFLG-----KELSERTVESILHHTSFQEMKKNPAANYETM---LPTLmdHSISPFLRKGIS 453
Cdd:PLN02164  236 FLKYETMRADPLPYVKRLAEFMGygftaEEEEKGVVEKVVKLCSFETLKNLEANKGEKDredRPAV--YANSAYFRKGKV 313

                         330       340
                  ....*....|....*....|....*...
gi 1772567150 454 GDWKNHFTVAQNERFDQHYQELMAGSDL 481
Cdd:PLN02164  314 GDWQNYLTPEMAARIDGLMEEKFKGTGL 341
LpsS COG4424
LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];
227-416 8.73e-06

LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443539  Cd Length: 238  Bit Score: 46.93  E-value: 8.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 227 QARPDDLLISTYPKSGTTWLSEIM----------------DMIYHNGDVEKCRRDAIYNRvpFLE--LKVSKSLCGV--- 285
Cdd:COG4424     3 TRPFRSYVICATPRSGSTLLCELLnatgvagcpgeyfnppFIPEWARGFLLGDRDRDPDE--YLRaiRRAGTTPNGVfgf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 286 ----DQLentpsPRLVKTHLPvqlLPTSFweKDCKIIYMARNpkDVV---ISYY------YFHQMAKIHHDPGTKAEF-L 351
Cdd:COG4424    81 klfwDQL-----PRLLQRALR---LLAAF--PDLKFIHLTRR--DKLaqaVSLViaqqtgQWHSDADDALAPTAPPEYdA 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1772567150 352 ENFMAgkvpygsWYDHVRGW---WE---KKREKKILYLFYEDMKKDPRQEVQKILQFLGKELSERTVESIL 416
Cdd:COG4424   149 EEIAR-------LLEALQDFearWEawfARTGITPLEITYEDLAADPVEVLNRVLDFLGVDPPLAPLRPAL 212
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
230-480 1.42e-118

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 348.18  E-value: 1.42e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 230 PDDLLISTYPKSGTTWLSEIMDMIYHNGDVEKCRRDAI---YNRVPFLELKV----SKSLCGVDQLENTPSPRLVKTHLP 302
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRGDFEKSEEPHLfnnHNRSPFLEWYPgdtyFDVAEGPVRLNALPSPRIIKTHLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 303 VQLLPTSFWEKDCKIIYMARNPKDVVISYYYFHQMAKIHHDPGTKAEFLENFMAGKVPYGSWYDHVRGWWEKKREKKILY 382
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVNCGSYFDHVKGWWKLRPPGNILF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 383 LFYEDMKKDPRQEVQKILQFLGKELSERTVESILHHTSFQEMKKNPAANYETMLPtlmdhSISPFLRKGISGDWKNHFTV 462
Cdd:pfam00685 161 LRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLSFENMKGNPCLNYSKLPK-----EVSPFFRKGLVGDWKNYFTP 235

                         250
                  ....*....|....*...
gi 1772567150 463 AQNERFDQHYQELMAGSD 480
Cdd:pfam00685 236 EQAEKFDEIYQEKMKGTG 253
PLN02164 PLN02164
sulfotransferase
 158-481 1.48e-34

sulfotransferase


Pssm-ID: 177822  Cd Length: 346  Bit Score: 132.35  E-value: 1.48e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 158 SSTTPGTVLAQVPASSEVVKATSREDSQCCV-DPLSAMEQEDAIRQE--LGSLHGIPLYKSFIEGWPQVKA-FQARPDDL 233
Cdd:PLN02164    3 SKTLNDTVTTVPSHEEAVTEPTEFEKNQKRYqDLIATLPHKKGWRPKepLIEYGGHWWLQPLLEGLLHAQEfFQARPNDF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 234 LISTYPKSGTTWLSEIMDMIyhngdVEKCRRDAIYNR---------VPFLELKVSkSLCGVDQLENTPSPrLVKTHLPVQ 304
Cdd:PLN02164   83 LVCSYPKTGTTWLKALTFAI-----ANRSRFDDSSNPllkrnphefVPYIEIDFP-FFPSVDVLKDKGNT-LFSTHIPYG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 305 LLPTSFWEKDCKIIYMARNPKDVVISYYYFHQMAKIHHDP-GTKAEFLENFMAGKVPYGSWYDHVRGWWEKKREK--KIL 381
Cdd:PLN02164  156 LLPDSVVKSGCKMVYIWRDPKDTFISMWTFLHKERSQQGPlNSLEESFDMFCRGLSVYGPYLDHVLGYWKAYQENpdRIL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 382 YLFYEDMKKDPRQEVQKILQFLG-----KELSERTVESILHHTSFQEMKKNPAANYETM---LPTLmdHSISPFLRKGIS 453
Cdd:PLN02164  236 FLKYETMRADPLPYVKRLAEFMGygftaEEEEKGVVEKVVKLCSFETLKNLEANKGEKDredRPAV--YANSAYFRKGKV 313

                         330       340
                  ....*....|....*....|....*...
gi 1772567150 454 GDWKNHFTVAQNERFDQHYQELMAGSDL 481
Cdd:PLN02164  314 GDWQNYLTPEMAARIDGLMEEKFKGTGL 341
Sulfotransfer_3 pfam13469
Sulfotransferase family;
239-409 6.04e-09

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 55.37  E-value: 6.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 239 PKSGTTWLSEIMD---MIYHNGDVEkcrrdAIYNRVPFLELKVSKSLcgvDQLENTPSP--RLV-KT-----HLP--VQL 305
Cdd:pfam13469   7 PRSGTTLLHRLLAahpDVRPPEETW-----FVIPRILALLQAWGKSL---EALARVPSYarWLCdKSpshlfHLDllLKA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 306 LPtsfwekDCKIIYMARNPKDVVISYYYfhQMAKIHHDP--GTKAEFLENFMAGkvpygsWYDHVRGW---WEKKREKKI 380
Cdd:pfam13469  79 FP------DAKFIHLHRDPVDTVISSYC--SLFGFTLSSysTAFLRDIGLALAR------WSRAYERLmaaRARVPPGRF 144

                         170       180
                  ....*....|....*....|....*....
gi 1772567150 381 LYLFYEDMKKDPRQEVQKILQFLGKELSE 409
Cdd:pfam13469 145 LDVRYEDLVADPEGTLRRILEFLGLPWDD 173
LpsS COG4424
LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];
227-416 8.73e-06

LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443539  Cd Length: 238  Bit Score: 46.93  E-value: 8.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 227 QARPDDLLISTYPKSGTTWLSEIM----------------DMIYHNGDVEKCRRDAIYNRvpFLE--LKVSKSLCGV--- 285
Cdd:COG4424     3 TRPFRSYVICATPRSGSTLLCELLnatgvagcpgeyfnppFIPEWARGFLLGDRDRDPDE--YLRaiRRAGTTPNGVfgf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1772567150 286 ----DQLentpsPRLVKTHLPvqlLPTSFweKDCKIIYMARNpkDVV---ISYY------YFHQMAKIHHDPGTKAEF-L 351
Cdd:COG4424    81 klfwDQL-----PRLLQRALR---LLAAF--PDLKFIHLTRR--DKLaqaVSLViaqqtgQWHSDADDALAPTAPPEYdA 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1772567150 352 ENFMAgkvpygsWYDHVRGW---WE---KKREKKILYLFYEDMKKDPRQEVQKILQFLGKELSERTVESIL 416
Cdd:COG4424   149 EEIAR-------LLEALQDFearWEawfARTGITPLEITYEDLAADPVEVLNRVLDFLGVDPPLAPLRPAL 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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