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Conserved domains on  [gi|1718143729|gb|QDX30584|]
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glycosyltransferase family 2 protein [Dickeya poaceiphila]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 10135931)

glycosyltransferase family 2 protein transfers sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 8-224 1.19e-85

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


:

Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 256.02  E-value: 1.19e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQG---KIRLYTGEGGLGAMKNFRRAIAC 84
Cdd:cd04196     1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKE---YIDKdpfIIILIRNGKNLGVARNFESLLQA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  85 CEDNYIALCDQDDYWVPEKLERLLRKVKSHERggtmPVLAFSDLEIVNAALEPLFPSFYRASiKSSAASQPEDFVVSNHI 164
Cdd:cd04196    78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDK----PLLVYSDLELVDENGNPIGESFFEYQ-KIKPGTSFNNLLFQNVV 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1718143729 165 PGCAMLFNRALKQLVEPMPDDIR-MHDWWIAMIAAHSGKIAYIDKPLIKYRQHGNNTVGAP 224
Cdd:cd04196   153 TGCTMAFNRELLELALPFPDADViMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGAN 213
 
Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 8-224 1.19e-85

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 256.02  E-value: 1.19e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQG---KIRLYTGEGGLGAMKNFRRAIAC 84
Cdd:cd04196     1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKE---YIDKdpfIIILIRNGKNLGVARNFESLLQA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  85 CEDNYIALCDQDDYWVPEKLERLLRKVKSHERggtmPVLAFSDLEIVNAALEPLFPSFYRASiKSSAASQPEDFVVSNHI 164
Cdd:cd04196    78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDK----PLLVYSDLELVDENGNPIGESFFEYQ-KIKPGTSFNNLLFQNVV 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1718143729 165 PGCAMLFNRALKQLVEPMPDDIR-MHDWWIAMIAAHSGKIAYIDKPLIKYRQHGNNTVGAP 224
Cdd:cd04196   153 TGCTMAFNRELLELALPFPDADViMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGAN 213
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 6-219 1.47e-28

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 109.02  E-value: 1.47e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRAIACC 85
Cdd:COG0463     3 LVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRELAA-KDPRIRVIRLERNRGKGAARNAGLAAA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  86 EDNYIALCDQDDYWVPEKLERLLRKVKSHERGGTMPVLAFSDLEIVNAALEPLFPSFYRAsikssaasqpedFVVSNHIP 165
Cdd:COG0463    82 RGDYIAFLDADDQLDPEKLEELVAALEEGPADLVYGSRLIREGESDLRRLGSRLFNLVRL------------LTNLPDST 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1718143729 166 GCAMLFNRALkqLVEPMPDDIRMHDWWIAMIAAHSGKIAYIDkplIKYRQHGNN 219
Cdd:COG0463   150 SGFRLFRREV--LEELGFDEGFLEDTELLRALRHGFRIAEVP---VRYRAGESK 198
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 8-177 1.03e-19

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 84.37  E-value: 1.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDV-IVnVCDDGSRDNTLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRAIACCE 86
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFeII-VVDDGSTDGTVEIAEEYAK-KDPRVRVIRLPENRGKAGARNAGLRAAT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  87 DNYIALCDQDDYWVPEKLERLLRKVKSHERGGTMPVLAFSDLEIVNaalEPLFPSFYRASIKSSAASQPEDFVVSNHIPG 166
Cdd:pfam00535  79 GDYIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETGE---YRRASRITLSRLPFFLGLRLLGLNLPFLIGG 155

                         170
                  ....*....|.
gi 1718143729 167 CAMLFNRALKQ 177
Cdd:pfam00535 156 FALYRREALEE 166
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-108 1.17e-07

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 52.36  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   1 MTGHDRISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHElYQQGKIRLYTGE-GGLGAMKNfr 79
Cdd:PRK10073    2 MNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIVNDGSTDNSVEIAKHYA-ENYPHVRLLHQAnAGVSVARN-- 78

                          90       100
                  ....*....|....*....|....*....
gi 1718143729  80 RAIACCEDNYIALCDQDDYWVPEKLERLL 108
Cdd:PRK10073   79 TGLAVATGKYVAFPDADDVVYPTMYETLM 107
 
Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 8-224 1.19e-85

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 256.02  E-value: 1.19e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQG---KIRLYTGEGGLGAMKNFRRAIAC 84
Cdd:cd04196     1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKE---YIDKdpfIIILIRNGKNLGVARNFESLLQA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  85 CEDNYIALCDQDDYWVPEKLERLLRKVKSHERggtmPVLAFSDLEIVNAALEPLFPSFYRASiKSSAASQPEDFVVSNHI 164
Cdd:cd04196    78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDK----PLLVYSDLELVDENGNPIGESFFEYQ-KIKPGTSFNNLLFQNVV 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1718143729 165 PGCAMLFNRALKQLVEPMPDDIR-MHDWWIAMIAAHSGKIAYIDKPLIKYRQHGNNTVGAP 224
Cdd:cd04196   153 TGCTMAFNRELLELALPFPDADViMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGAN 213
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 6-219 1.47e-28

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 109.02  E-value: 1.47e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRAIACC 85
Cdd:COG0463     3 LVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRELAA-KDPRIRVIRLERNRGKGAARNAGLAAA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  86 EDNYIALCDQDDYWVPEKLERLLRKVKSHERGGTMPVLAFSDLEIVNAALEPLFPSFYRAsikssaasqpedFVVSNHIP 165
Cdd:COG0463    82 RGDYIAFLDADDQLDPEKLEELVAALEEGPADLVYGSRLIREGESDLRRLGSRLFNLVRL------------LTNLPDST 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1718143729 166 GCAMLFNRALkqLVEPMPDDIRMHDWWIAMIAAHSGKIAYIDkplIKYRQHGNN 219
Cdd:COG0463   150 SGFRLFRREV--LEELGFDEGFLEDTELLRALRHGFRIAEVP---VRYRAGESK 198
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 8-177 1.03e-19

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 84.37  E-value: 1.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDV-IVnVCDDGSRDNTLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRAIACCE 86
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFeII-VVDDGSTDGTVEIAEEYAK-KDPRVRVIRLPENRGKAGARNAGLRAAT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  87 DNYIALCDQDDYWVPEKLERLLRKVKSHERGGTMPVLAFSDLEIVNaalEPLFPSFYRASIKSSAASQPEDFVVSNHIPG 166
Cdd:pfam00535  79 GDYIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETGE---YRRASRITLSRLPFFLGLRLLGLNLPFLIGG 155

                         170
                  ....*....|.
gi 1718143729 167 CAMLFNRALKQ 177
Cdd:pfam00535 156 FALYRREALEE 166
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
6-109 2.95e-17

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 78.50  E-value: 2.95e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQGKIRLYTGEGGLGAMKNFRRAIACC 85
Cdd:COG1216     4 KVSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVVDNGSTDGTAELLAA---LAFPRVRVIRNPENLGFAAARNLGLRAA 80

                          90       100
                  ....*....|....*....|....
gi 1718143729  86 EDNYIALCDQDDYWVPEKLERLLR 109
Cdd:COG1216    81 GGDYLLFLDDDTVVEPDWLERLLA 104
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 9-118 3.20e-17

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 77.16  E-value: 3.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHeLYQQGKIRLYTGEGGLGAMKNFRRAIACCEDN 88
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEEY-AKKDPRVIRVINEENQGLAAARNAGLKAARGE 79

                          90       100       110
                  ....*....|....*....|....*....|
gi 1718143729  89 YIALCDQDDYWVPEKLERLLRKVKSHERGG 118
Cdd:cd00761    80 YILFLDADDLLLPDWLERLVAELLADPEAD 109
GT_2_WfgS_like cd06433
WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella ...
 8-220 6.26e-15

WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133055 [Multi-domain]  Cd Length: 202  Bit Score: 71.81  E-value: 6.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   8 SIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQGKIRLYTGE-GGL-GAMkNfrRAIACC 85
Cdd:cd06433     1 SIITPTYNQAETLEETIDSVLSQTYPNIEYIVIDGGSTDGTVDIIKK---YEDKITYWISEPdKGIyDAM-N--KGIALA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  86 EDNYIALCDQDDYWVPEKLERLLRKVKSHERggtmPVLAFSDLEIVNaaleplfPSFYRASIKSSAASQPEDFVVSNHIP 165
Cdd:cd06433    75 TGDIIGFLNSDDTLLPGALLAVVAAFAEHPE----VDVVYGDVLLVD-------ENGRVIGRRRPPPFLDKFLLYGMPIC 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1718143729 166 GCAMLFNRALKQLVEPMPDDIRM---HDWWIAMIAAHsGKIAYIDKPLIKYRQHGNNT 220
Cdd:cd06433   144 HQATFFRRSLFEKYGGFDESYRIaadYDLLLRLLLAG-KIFKYLPEVLAAFRLGGVSS 200
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 6-126 1.99e-10

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 60.53  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQTHQ----DVIVnvCDDGSRDNTLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRA 81
Cdd:COG1215    30 RVSVIIPAYNEEAVIEETLRSLLAQDYPkeklEVIV--VDDGSTDETAEIARELAA-EYPRVRVIERPENGGKAAALNAG 106

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1718143729  82 IACCEDNYIALCDQDDYWVPEKLERLLRKVKSHERGGTMPVLAFS 126
Cdd:COG1215   107 LKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGVGASGANLAFR 151
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 6-204 1.34e-08

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 54.51  E-value: 1.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSI--QHQTHQDVIVNVCDDGSRDNTLDVVRShelYQQGKIRLYTGEGGLGAMKNFRRAIA 83
Cdd:cd06439    30 TVTIIIPAYNEEAVIEAKLENLlaLDYPRDRLEIIVVSDGSTDGTAEIARE---YADKGVKLLRFPERRGKAAALNRALA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  84 CCEDNYIALCDQDDYWVPEKLERLLRkvksherggtmpvlAFSDLEI--VNAALEPLFP-------SFYRAS---IK--- 148
Cdd:cd06439   107 LATGEIVVFTDANALLDPDALRLLVR--------------HFADPSVgaVSGELVIVDGggsgsgeGLYWKYenwLKrae 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1718143729 149 SSAASqpedfVVSNHipGCAMLFNRalkQLVEPMPDDIRMHDWWIAMIAAHSGKIA 204
Cdd:cd06439   173 SRLGS-----TVGAN--GAIYAIRR---ELFRPLPADTINDDFVLPLRIARQGYRV 218
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-108 1.17e-07

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 52.36  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   1 MTGHDRISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHElYQQGKIRLYTGE-GGLGAMKNfr 79
Cdd:PRK10073    2 MNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIVNDGSTDNSVEIAKHYA-ENYPHVRLLHQAnAGVSVARN-- 78

                          90       100
                  ....*....|....*....|....*....
gi 1718143729  80 RAIACCEDNYIALCDQDDYWVPEKLERLL 108
Cdd:PRK10073   79 TGLAVATGKYVAFPDADDVVYPTMYETLM 107
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 9-115 4.82e-07

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 49.11  E-value: 4.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQTHQDVIVN--VCDDGSRDNTLDVVRSH-ELYQQGKIRLYTGEGGLGAmkNFRRAIACC 85
Cdd:cd04179     1 VVIPAYNEEENIPELVERLLAVLEEGYDYEiiVVDDGSTDGTAEIARELaARVPRVRVIRLSRNFGKGA--AVRAGFKAA 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1718143729  86 EDNYIALCD---QDDywvPEKLERLLRKVKSHE 115
Cdd:cd04179    79 RGDIVVTMDadlQHP---PEDIPKLLEKLLEGG 108
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 6-136 2.65e-06

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 47.61  E-value: 2.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQT--HQDVIVNVCDDGSRDNTLDVVRShelYQQ--GKIRLYTGEGGLGAmKNFRRA 81
Cdd:cd02525     1 FVSIIIPVRNEEKYIEELLESLLNQSypKDLIEIIVVDGGSTDGTREIVQE---YAAkdPRIRLIDNPKRIQS-AGLNIG 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1718143729  82 IACCEDNYIALCDQDDYWVPEKLERLLRKVKSHER---GGTMPVLAFSDLEIVNAALE 136
Cdd:cd02525    77 IRNSRGDIIIRVDAHAVYPKDYILELVEALKRTGAdnvGGPMETIGESKFQKAIAVAQ 134
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 4-114 3.27e-06

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 47.37  E-value: 3.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   4 HDRISIALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRS-HELYQQGKIRLYTGE---GGLGAMKNFR 79
Cdd:pfam13641   1 PPDVSVVVPAFNEDSVLGRVLEAILAQPYPPVEVVVVVNPSDAETLDVAEEiAARFPDVRLRVIRNArllGPTGKSRGLN 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1718143729  80 RAIACCEDNYIALCDQDDYWVPEKLERLLRKVKSH 114
Cdd:pfam13641  81 HGFRAVKSDLVVLHDDDSVLHPGTLKKYVQYFDSP 115
Glyco_tranf_2_2 pfam10111
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 9-113 1.10e-05

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 313356 [Multi-domain]  Cd Length: 276  Bit Score: 46.12  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRS------HELYQQGKIRLYtgegGLGAMKNfrRAI 82
Cdd:pfam10111   4 IPVYNGEKTHWIQERILNQTFQYDPEFELIIINDGSTDKTLEEVSSikdhnlQVYYPNAPDTTY----SLAASRN--RGT 77

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1718143729  83 ACCEDNYIALCDQDDYWVPEKLERLLRKVKS 113
Cdd:pfam10111  78 SHAIGEYISFIDGDCLWSPDKFEKQLKIATS 108
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 13-121 1.79e-05

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 44.93  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  13 TYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRS-HELYQQGKIRLYTGEGGLGAMKN-FRRAIACcEDNYI 90
Cdd:cd04185     5 TYNRLDLLKECLDALLAQTRPPDHIIVIDNASTDGTAEWLTSlGDLDNIVYLRLPENLGGAGGFYEgVRRAYEL-GYDWI 83

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1718143729  91 ALCDQDDYWVPEKLERLLRKVKSHERGGTMP 121
Cdd:cd04185    84 WLMDDDAIPDPDALEKLLAYADKDNPQFLAP 114
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 13-118 1.81e-05

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 44.09  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729  13 TYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSHElyqqGKIRLYTGEGGLGAMKNFRRAIACCEDNYIAL 92
Cdd:cd04186     5 NYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSVELLRELF----PEVRLIRNGENLGFGAGNNQGIREAKGDYVLL 80

                          90       100
                  ....*....|....*....|....*.
gi 1718143729  93 CDQDDYWVPEKLERLLRKVKSHERGG 118
Cdd:cd04186    81 LNPDTVVEPGALLELLDAAEQDPDVG 106
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 6-106 8.85e-05

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 42.58  E-value: 8.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNG-GRYIKQQLDSIQHQTHQDVIVNVCDDGSRDN-TLDVVRSHELyQQGKIRLYTGEGGLGAMKNFRRAIA 83
Cdd:cd04184     2 LISIVMPVYNTpEKYLREAIESVRAQTYPNWELCIADDASTDPeVKRVLKKYAA-QDPRIKVVFREENGGISAATNSALE 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 1718143729  84 CCEDNYIALCDQDD-------YWVPEKLER 106
Cdd:cd04184    81 LATGEFVALLDHDDelaphalYEVVKALNE 110
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 9-118 9.74e-05

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 42.21  E-value: 9.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQTHQDVIVNVCDDGSRDNTLDVVRSH-ELYQQGKIRLYTGEGGlGAMKNFRRAIACCED 87
Cdd:cd06423     1 IIVPAYNEEAVIERTIESLLALDYPKLEVIVVDDGSTDDTLEILEELaALYIRRVLVVRDKENG-GKAGALNAGLRHAKG 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1718143729  88 NYIALCDQDDYWVPEKLERLLRKVKSHERGG 118
Cdd:cd06423    80 DIVVVLDADTILEPDALKRLVVPFFADPKVG 110
Beta4Glucosyltransferase cd02511
UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of ...
 6-113 9.84e-05

UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.


Pssm-ID: 133005 [Multi-domain]  Cd Length: 229  Bit Score: 42.66  E-value: 9.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   6 RISIALATYNGGRYIKQQLDSIQHQTHQDVIVnvcDDGSRDNTLDVVRSHelyqqgKIRLYTGE-GGLGAMKNFrrAIAC 84
Cdd:cd02511     1 TLSVVIITKNEERNIERCLESVKWAVDEIIVV---DSGSTDRTVEIAKEY------GAKVYQRWwDGFGAQRNF--ALEL 69

                          90       100
                  ....*....|....*....|....*....
gi 1718143729  85 CEDNYIALCDQdDYWVPEKLERLLRKVKS 113
Cdd:cd02511    70 ATNDWVLSLDA-DERLTPELADEILALLA 97
DPM1_like cd06442
DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to ...
 9-115 6.20e-04

DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133062 [Multi-domain]  Cd Length: 224  Bit Score: 40.21  E-value: 6.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQT---HQDVIVnVcDDGSRDNTLDVVRSHElYQQGKIRLY--TGEGGLGA--MKNFRRA 81
Cdd:cd06442     1 IIIPTYNERENIPELIERLDAALkgiDYEIIV-V-DDNSPDGTAEIVRELA-KEYPRVRLIvrPGKRGLGSayIEGFKAA 77

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1718143729  82 IAccedNYIALCDQD---DywvPEKLERLLRKVKSHE 115
Cdd:cd06442    78 RG----DVIVVMDADlshP---PEYIPELLEAQLEGG 107
beta3GnTL1_like cd06913
Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of ...
 9-114 1.06e-03

Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine ; This family includes human Beta3GnTL1 and related eukaryotic proteins. Human Beta3GnTL1 is a putative beta-1,3-N-acetylglucosaminyltransferase. Beta3GnTL1 is expressed at various levels in most of tissues examined. Beta 1, 3-N-acetylglucosaminyltransferase has been found to be essential for the formation of poly-N-acetyllactosamine. Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats. It is often an important part of cell-type-specific oligosaccharide structures and some functional oligosaccharides. It has been shown that the structure and biosynthesis of poly-N-acetyllactosamine display a dramatic change during development and oncogenesis. Several members of beta-1, 3-N-acetylglucosaminyltransferase have been identified.


Pssm-ID: 133063 [Multi-domain]  Cd Length: 219  Bit Score: 39.75  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   9 IALATYNGGRYIKQQLDSIQHQTHQDVI-VNVCDDGSRDNTLDVVRSHE--LYQQGKIRLYTGEG-----GLGAMKNfrR 80
Cdd:cd06913     1 IILPVHNGEQWLDECLESVLQQDFEGTLeLSVFNDASTDKSAEIIEKWRkkLEDSGVIVLVGSHNspspkGVGYAKN--Q 78

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1718143729  81 AIACCEDNYIALCDQDDYWVPEKLERLLRKVKSH 114
Cdd:cd06913    79 AIAQSSGRYLCFLDSDDVMMPQRIRLQYEAALQH 112
PLN02726 PLN02726
dolichyl-phosphate beta-D-mannosyltransferase
 1-110 7.89e-03

dolichyl-phosphate beta-D-mannosyltransferase


Pssm-ID: 215385 [Multi-domain]  Cd Length: 243  Bit Score: 36.98  E-value: 7.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718143729   1 MTGHDRISIALATYNGGRYIKQqLDSIQHQTHQDVI---VNVCDDGSRDNTLDVVRS-HELYQQGKIRLYTGEGGLGAMK 76
Cdd:PLN02726    5 GEGAMKYSIIVPTYNERLNIAL-IVYLIFKALQDVKdfeIIVVDDGSPDGTQDVVKQlQKVYGEDRILLRPRPGKLGLGT 83

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1718143729  77 NFRRAIACCEDNYIALCDQDDYWVPEKLERLLRK 110
Cdd:PLN02726   84 AYIHGLKHASGDFVVIMDADLSHHPKYLPSFIKK 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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