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Conserved domains on  [gi|1276655780|gb|ATV19638|]
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GDP-mannose dehydrogenase [Pseudomonas syringae pv. actinidiae]

Protein Classification

nucleotide sugar dehydrogenase( domain architecture ID 11496319)

nucleotide sugar dehydrogenase such as GDP-mannose 6-dehydrogenase, which catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 1-421 6.62e-169

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


:

Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 480.19  E-value: 6.62e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLS 80
Cdd:TIGR03026   1 MKIAVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIYEPGLDELLAKALKAGRLRATTDYEEAIRDADVI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLRDKNtrhTIVVRSTVLPGTVANVVIPILEDcSGKKAGVDFGVAVNPEFLR 160
Cdd:TIGR03026  81 IICVPTPLKEDGSPDLSYVESAAETIAKHLRKGA---TVVLESTVPPGTTEEVVKPILER-SGLKLGEDFYLAYNPEFLR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLPPMTVIGEfDKASGDVLQSLYEEL-DAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGR 239
Cdd:TIGR03026 157 EGNAVHDLLHPDRIVGGE-TEEAGEAVAELYSPIiDGPVLVTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVY 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 240 EVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASY----DTRK 315
Cdd:TIGR03026 236 EVIEAAGTDP--RIGFNFLNPGPGVGGHCIPKDPLALIAKAKELGYNPELIEAAREINDSQPDYVVEKIKDLlgplKGKT 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 316 VALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGANkdyieskiphvsslLNSDFDQVINDSDVII 395
Cdd:TIGR03026 314 VLILGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLP--------------SIDDLEEALKGADALV 379

                         410       420       430
                  ....*....|....*....|....*....|
gi 1276655780 396 LGNRDERFRALANK----TPEGKRVIDLVG 421
Cdd:TIGR03026 380 ILTDHSEFKDLDLEkikdLMKGKVVVDTRN 409
 
Name Accession Description Interval E-value
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 1-421 6.62e-169

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 480.19  E-value: 6.62e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLS 80
Cdd:TIGR03026   1 MKIAVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIYEPGLDELLAKALKAGRLRATTDYEEAIRDADVI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLRDKNtrhTIVVRSTVLPGTVANVVIPILEDcSGKKAGVDFGVAVNPEFLR 160
Cdd:TIGR03026  81 IICVPTPLKEDGSPDLSYVESAAETIAKHLRKGA---TVVLESTVPPGTTEEVVKPILER-SGLKLGEDFYLAYNPEFLR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLPPMTVIGEfDKASGDVLQSLYEEL-DAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGR 239
Cdd:TIGR03026 157 EGNAVHDLLHPDRIVGGE-TEEAGEAVAELYSPIiDGPVLVTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVY 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 240 EVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASY----DTRK 315
Cdd:TIGR03026 236 EVIEAAGTDP--RIGFNFLNPGPGVGGHCIPKDPLALIAKAKELGYNPELIEAAREINDSQPDYVVEKIKDLlgplKGKT 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 316 VALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGANkdyieskiphvsslLNSDFDQVINDSDVII 395
Cdd:TIGR03026 314 VLILGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLP--------------SIDDLEEALKGADALV 379

                         410       420       430
                  ....*....|....*....|....*....|
gi 1276655780 396 LGNRDERFRALANK----TPEGKRVIDLVG 421
Cdd:TIGR03026 380 ILTDHSEFKDLDLEkikdLMKGKVVVDTRN 409
Ugd COG1004
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
1-353 2.52e-128

UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440628 [Multi-domain]  Cd Length: 436  Bit Score: 377.82  E-value: 2.52e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLS 80
Cdd:COG1004     1 MKIAVIGTGYVGLVTAACLAELGHEVTCVDIDEEKIEALNAGEIPIYEPGLEELVARNVAAGRLRFTTDLAEAVAEADVV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLRDkntRHTIVVRSTVLPGTVANVVIPILEdcSGKKAGVDFGVAVNPEFLR 160
Cdd:COG1004    81 FIAVGTPSDEDGSADLSYVLAAARSIGEALKG---YKVVVTKSTVPVGTADRVRAIIAE--ELRGAGVDFDVVSNPEFLR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLPPMTVIGEFDKASGDVLQSLYEEL---DAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVD 237
Cdd:COG1004   156 EGSAVEDFLRPDRIVIGVDSERAAEVLRELYAPFvrnGTPIIVTDLRSAELIKYAANAFLATKISFINEIANLCEKVGAD 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 238 GREVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASY-----D 312
Cdd:COG1004   236 VEEVARGIGLDS--RIGPKFLYAGIGYGGSCFPKDVRALIATARELGYDLRLLEAVEEVNERQKRRLVEKIREHlggdlK 313

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1276655780 313 TRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFD 353
Cdd:COG1004   314 GKTIAVLGLAFKPNTDDMRESPALDIIEALLEAGARVRAYD 354
UDPG_MGDP_dh_N pfam03721
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ...
 1-190 2.25e-73

UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 397677 [Multi-domain]  Cd Length: 186  Bit Score: 228.29  E-value: 2.25e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLaTGKLRGTTDFAEAIRATDLS 80
Cdd:pfam03721   1 MKISVIGLGYVGLPTAACLAEIGHDVIGVDIDEEKVDKLNSGQIPIYEPGLDELVKANV-SGRLSFTTDYSTAIEEADVI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDL-ELDYIESVCREIGYVLRdknTRHTIVVRSTVLPGTVANVVIPILEDCSGKKaGVDFGVAVNPEFL 159
Cdd:pfam03721  80 FIAVGTPSKKGGGAaDLKYVESAARSIAPHLK---KGKVVVVKSTVPVGTTENLVKPIIEEGGKKV-GVDFDVASNPEFL 155

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1276655780 160 RESTAIKDYDLPPMTVIGEFDKASGDVLQSL 190
Cdd:pfam03721 156 REGSAVYDLFNPDRVVIGVTEKCAEAALEEL 186
PRK15057 PRK15057
UDP-glucose 6-dehydrogenase; Provisional
 1-409 6.21e-41

UDP-glucose 6-dehydrogenase; Provisional


Pssm-ID: 185017 [Multi-domain]  Cd Length: 388  Bit Score: 149.79  E-value: 6.21e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGaVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGlaTGKLRGTTDFAEAIRATDLS 80
Cdd:PRK15057    1 MKITISGTGYVG-LSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSD--KIHFNATLDKNEAYRDADYV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MIcvGTPSK---KNGDLELDYIESVCREIGYVlrdkNTRHTIVVRSTVLPGTVANVvipiledcsGKKAGVDfGVAVNPE 157
Cdd:PRK15057   78 II--ATPTDydpKTNYFNTSSVESVIKDVVEI----NPYAVMVIKSTVPVGFTAAM---------HKKYRTE-NIIFSPE 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 158 FLRESTAIKDYDLPPMTVIGEFDKAS---GDVLQSLYEELDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAV 234
Cdd:PRK15057  142 FLREGKALYDNLHPSRIVIGERSERAerfAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 235 GVDGREVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTyrAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASYDTR 314
Cdd:PRK15057  222 GLNTRQIIEGVCLDP--RIGNHYNNPSFGYGGYCLPKDTKQLL--ANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQ 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 315 KVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVhgankdyieskiphVSSLLNSDFDQVINDSDVI 394
Cdd:PRK15057  298 VVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSF--------------FNSRLERDLATFKQQADVI 363

                         410
                  ....*....|....*
gi 1276655780 395 ILGNRDERFRALANK 409
Cdd:PRK15057  364 ISNRMAEELKDVADK 378
UDPG_MGDP_dh_C smart00984
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ...
 317-421 1.63e-15

UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 214954 [Multi-domain]  Cd Length: 99  Bit Score: 71.77  E-value: 1.63e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  317 ALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDsnveyarvhgankDYIESKIPHVSSLLNSDFDQVINDSDVIIL 396
Cdd:smart00984   1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYD-------------PYAMEEAREYGLTYVSDLEEALKGADAVVI 67

                           90       100
                   ....*....|....*....|....*....
gi 1276655780  397 GNRDERFRALA----NKTPEGKRVIDLVG 421
Cdd:smart00984  68 ATEHDEFRSLDpeelKDLMKKPVVVDGRN 96
 
Name Accession Description Interval E-value
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 1-421 6.62e-169

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 480.19  E-value: 6.62e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLS 80
Cdd:TIGR03026   1 MKIAVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIYEPGLDELLAKALKAGRLRATTDYEEAIRDADVI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLRDKNtrhTIVVRSTVLPGTVANVVIPILEDcSGKKAGVDFGVAVNPEFLR 160
Cdd:TIGR03026  81 IICVPTPLKEDGSPDLSYVESAAETIAKHLRKGA---TVVLESTVPPGTTEEVVKPILER-SGLKLGEDFYLAYNPEFLR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLPPMTVIGEfDKASGDVLQSLYEEL-DAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGR 239
Cdd:TIGR03026 157 EGNAVHDLLHPDRIVGGE-TEEAGEAVAELYSPIiDGPVLVTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVY 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 240 EVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASY----DTRK 315
Cdd:TIGR03026 236 EVIEAAGTDP--RIGFNFLNPGPGVGGHCIPKDPLALIAKAKELGYNPELIEAAREINDSQPDYVVEKIKDLlgplKGKT 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 316 VALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGANkdyieskiphvsslLNSDFDQVINDSDVII 395
Cdd:TIGR03026 314 VLILGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLP--------------SIDDLEEALKGADALV 379

                         410       420       430
                  ....*....|....*....|....*....|
gi 1276655780 396 LGNRDERFRALANK----TPEGKRVIDLVG 421
Cdd:TIGR03026 380 ILTDHSEFKDLDLEkikdLMKGKVVVDTRN 409
Ugd COG1004
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
1-353 2.52e-128

UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440628 [Multi-domain]  Cd Length: 436  Bit Score: 377.82  E-value: 2.52e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLS 80
Cdd:COG1004     1 MKIAVIGTGYVGLVTAACLAELGHEVTCVDIDEEKIEALNAGEIPIYEPGLEELVARNVAAGRLRFTTDLAEAVAEADVV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLRDkntRHTIVVRSTVLPGTVANVVIPILEdcSGKKAGVDFGVAVNPEFLR 160
Cdd:COG1004    81 FIAVGTPSDEDGSADLSYVLAAARSIGEALKG---YKVVVTKSTVPVGTADRVRAIIAE--ELRGAGVDFDVVSNPEFLR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLPPMTVIGEFDKASGDVLQSLYEEL---DAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVD 237
Cdd:COG1004   156 EGSAVEDFLRPDRIVIGVDSERAAEVLRELYAPFvrnGTPIIVTDLRSAELIKYAANAFLATKISFINEIANLCEKVGAD 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 238 GREVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASY-----D 312
Cdd:COG1004   236 VEEVARGIGLDS--RIGPKFLYAGIGYGGSCFPKDVRALIATARELGYDLRLLEAVEEVNERQKRRLVEKIREHlggdlK 313

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1276655780 313 TRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFD 353
Cdd:COG1004   314 GKTIAVLGLAFKPNTDDMRESPALDIIEALLEAGARVRAYD 354
WecC COG0677
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];
2-396 2.04e-80

UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440441 [Multi-domain]  Cd Length: 413  Bit Score: 254.22  E-value: 2.04e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   2 RISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGlEELLQKGLATGKLRGTTDFaEAIRATDLSM 81
Cdd:COG0677     1 KIAVIGLGYVGLPLAVAFAKAGFRVIGFDINPERVEELNAGEDPILEPG-DELLAEAVAAGRLRATTDP-EALAEADVVI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  82 ICVGTPSKKNGDLELDYIESVCREIGYVLRdKNTrhTIVVRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEflRE 161
Cdd:COG0677    79 IAVPTPLDEDKEPDLSYLESASETIAPHLK-PGD--LVVLESTVYPGTTEEVCVPILEKRSGLKAGEDFFLAYSPE--RI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 162 STAIKDYDLPPMT-VIGEFDKASGDVLQSLYEE-LDAPIIR-KDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDG 238
Cdd:COG0677   154 NPGNKLHELRNIPkVVGGITPESAERAAALYGSvVTAGVVPvSSIKVAEAAKLIENTYRDVNIALANELALICDRLGIDV 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 239 REVMDvvcqdkALNLSQYYM--RPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQ----VQNAFDMVASYD 312
Cdd:COG0677   234 WEVIE------AANTKPGFLifYPGPGVGGHCIPVDPYYLTWKARELGYHPRLILAAREINDSMpeyvVERVVKALNEAG 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 313 TR----KVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGAnkdYIESkiphvssllnSDFDQVI 388
Cdd:COG0677   308 KSlkgaRVLVLGLAYKENVDDLRESPALDIIEELREYGAEVDVHDPYVDEEEVEGE---YGEL----------VDLEEAL 374


                  ....*...
gi 1276655780 389 NDSDVIIL 396
Cdd:COG0677   375 EGADAVVL 382
UDPG_MGDP_dh_N pfam03721
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ...
 1-190 2.25e-73

UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 397677 [Multi-domain]  Cd Length: 186  Bit Score: 228.29  E-value: 2.25e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLaTGKLRGTTDFAEAIRATDLS 80
Cdd:pfam03721   1 MKISVIGLGYVGLPTAACLAEIGHDVIGVDIDEEKVDKLNSGQIPIYEPGLDELVKANV-SGRLSFTTDYSTAIEEADVI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDL-ELDYIESVCREIGYVLRdknTRHTIVVRSTVLPGTVANVVIPILEDCSGKKaGVDFGVAVNPEFL 159
Cdd:pfam03721  80 FIAVGTPSKKGGGAaDLKYVESAARSIAPHLK---KGKVVVVKSTVPVGTTENLVKPIIEEGGKKV-GVDFDVASNPEFL 155

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1276655780 160 RESTAIKDYDLPPMTVIGEFDKASGDVLQSL 190
Cdd:pfam03721 156 REGSAVYDLFNPDRVVIGVTEKCAEAALEEL 186
PRK15057 PRK15057
UDP-glucose 6-dehydrogenase; Provisional
 1-409 6.21e-41

UDP-glucose 6-dehydrogenase; Provisional


Pssm-ID: 185017 [Multi-domain]  Cd Length: 388  Bit Score: 149.79  E-value: 6.21e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGaVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGlaTGKLRGTTDFAEAIRATDLS 80
Cdd:PRK15057    1 MKITISGTGYVG-LSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSD--KIHFNATLDKNEAYRDADYV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MIcvGTPSK---KNGDLELDYIESVCREIGYVlrdkNTRHTIVVRSTVLPGTVANVvipiledcsGKKAGVDfGVAVNPE 157
Cdd:PRK15057   78 II--ATPTDydpKTNYFNTSSVESVIKDVVEI----NPYAVMVIKSTVPVGFTAAM---------HKKYRTE-NIIFSPE 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 158 FLRESTAIKDYDLPPMTVIGEFDKAS---GDVLQSLYEELDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAV 234
Cdd:PRK15057  142 FLREGKALYDNLHPSRIVIGERSERAerfAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 235 GVDGREVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTyrAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASYDTR 314
Cdd:PRK15057  222 GLNTRQIIEGVCLDP--RIGNHYNNPSFGYGGYCLPKDTKQLL--ANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQ 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 315 KVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVhgankdyieskiphVSSLLNSDFDQVINDSDVI 394
Cdd:PRK15057  298 VVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSF--------------FNSRLERDLATFKQQADVI 363

                         410
                  ....*....|....*
gi 1276655780 395 ILGNRDERFRALANK 409
Cdd:PRK15057  364 ISNRMAEELKDVADK 378
PLN02353 PLN02353
probable UDP-glucose 6-dehydrogenase
 1-362 8.76e-40

probable UDP-glucose 6-dehydrogenase


Pssm-ID: 177986 [Multi-domain]  Cd Length: 473  Bit Score: 148.67  E-value: 8.76e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHD--VVGVDISSTKIDLINNGKSPIVEPGLEELLQKglATGK-LRGTTDFAEAIRAT 77
Cdd:PLN02353    2 VKICCIGAGYVGGPTMAVIALKCPDieVVVVDISVPRIDAWNSDQLPIYEPGLDEVVKQ--CRGKnLFFSTDVEKHVAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  78 DLSMICVGTPSKKNG-----DLELDYIESVCREIGYVLR-DKntrhtIVVRSTVLPGTVANVVIPILEDCSgkkAGVDFG 151
Cdd:PLN02353   80 DIVFVSVNTPTKTRGlgagkAADLTYWESAARMIADVSKsDK-----IVVEKSTVPVKTAEAIEKILTHNS---KGINFQ 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 152 VAVNPEFLRESTAIKDYDLPPMTVIGEFDKASG----DVLQSLYEELDAP--IIRKDIAVAEMIKYTCNVWHATKVTFAN 225
Cdd:PLN02353  152 ILSNPEFLAEGTAIEDLFKPDRVLIGGRETPEGqkavQALKDVYAHWVPEerIITTNLWSAELSKLAANAFLAQRISSVN 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 226 EIGNIAKAVGVDGREVMDVVCQD-----KALNlsqyymrPGFAFGGSCLPKDVRALTY--RAGSLDVDAPLLNSLMRSNT 298
Cdd:PLN02353  232 AMSALCEATGADVSQVSHAVGKDsrigpKFLN-------ASVGFGGSCFQKDILNLVYicECNGLPEVAEYWKQVIKMND 304

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1276655780 299 SQ--------VQNAFDMVASydtRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVH 362
Cdd:PLN02353  305 YQksrfvnrvVSSMFNTVSG---KKIAVLGFAFKKDTGDTRETPAIDVCKGLLGDKAKLSIYDPQVTEEQIQ 373
UDPG_MGDP_dh pfam00984
UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose ...
 205-297 1.34e-35

UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 460015 [Multi-domain]  Cd Length: 92  Bit Score: 126.72  E-value: 1.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 205 VAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGREVMDVVCQDKalNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLD 284
Cdd:pfam00984   1 SAELIKLAENAFLAVKISFINELANLCEALGADVWEVIEAAGTDP--RIGPKFLYPGPGVGGSCLPKDPRALIYLARELG 78

                          90
                  ....*....|...
gi 1276655780 285 VDAPLLNSLMRSN 297
Cdd:pfam00984  79 VPARLLEAAREVN 91
wecC PRK11064
UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional
 2-418 1.22e-28

UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional


Pssm-ID: 182940 [Multi-domain]  Cd Length: 415  Bit Score: 116.62  E-value: 1.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   2 RISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAiratDLSM 81
Cdd:PRK11064    5 TISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLDMVVKTAVEGGYLRATTTPEPA----DAFL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  82 ICVGTPSKKNGDLELDYIESVCREIGYVLRDKNtrhTIVVRSTVLPGT---VANVVIPILEDCS-----GKKAGVDfgVA 153
Cdd:PRK11064   81 IAVPTPFKGDHEPDLTYVEAAAKSIAPVLKKGD---LVILESTSPVGAteqMAEWLAEARPDLTfpqqaGEQADIN--IA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 154 VNPE------FLREstAIKDyDlppmTVIGEFDKASGDVLQSLYEE-LDAPIIRKDIAVAEMIKYTCNVWHATKVTFANE 226
Cdd:PRK11064  156 YCPErvlpgqVMVE--LIKN-D----RVIGGMTPVCSARASELYKIfLEGECVVTNSRTAEMCKLTENSFRDVNIAFANE 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 227 IGNIAKAVGVDGREVMDVVCQDKALNLSQyymrPGFAFGGSCLPkdvraltyragsldVD-------APLLNSLMRS--- 296
Cdd:PRK11064  229 LSLICADQGINVWELIRLANRHPRVNILQ----PGPGVGGHCIA--------------VDpwfivaqNPQQARLIRTare 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 297 -NTS-------QVQNAF-DMVASYDTR----KVALLGLSFKAGTDDLRESPLVELAEMLigkgfdlsifdsnveyARVHG 363
Cdd:PRK11064  291 vNDGkphwvidQVKAAVaDCLAATDKRasevKIACFGLAFKPNIDDLRESPAMEIAELI----------------AQWHS 354

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1276655780 364 ANKDYIEskiPHVSSLLNS--------DFDQVINDSDVIILGNRDERFRALANKTPEGKRVID 418
Cdd:PRK11064  355 GETLVVE---PNIHQLPKKldglvtlvSLDEALATADVLVMLVDHSQFKAINGDNVHQQWVVD 414
PRK15182 PRK15182
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB;
1-388 1.57e-16

Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB;


Pssm-ID: 185104 [Multi-domain]  Cd Length: 425  Bit Score: 81.27  E-value: 1.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAgCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLatgkLRGTTDFaEAIRATDLS 80
Cdd:PRK15182    7 VKIAIIGLGYVGLPLA-VEFGKSRQVVGFDVNKKRILELKNGVDVNLETTEEELREARY----LKFTSEI-EKIKECNFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPSKKNGDLELDYIESVCREIGYVLrdkNTRHTIVVRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEflR 160
Cdd:PRK15182   81 IITVPTPINTYKQPDLTPLIKASETVGTVL---NRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPE--R 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 161 ESTAIKDYDLppmTVIGEFDKASGDVLQSLYEELDAPIIR------KDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAV 234
Cdd:PRK15182  156 INPGDKKHRL---TNIKKITSGSTAQIAELIDEVYQQIISagtykaESIKVAEAAKVIENTQRDLNIALVNELAIIFNRL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 235 GVDGREVMDVVcqDKALNLSQYymRPGFAfGGSCLPKDVRALTYRAGSLDVDAPL------LNSLMRSNTSQ--VQNAFD 306
Cdd:PRK15182  233 NIDTEAVLRAA--GSKWNFLPF--RPGLV-GGHCIGVDPYYLTHKSQGIGYYPEIilagrrLNDNMGNYVSEqlIKAMIK 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 307 MVASYDTRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGankdyiESKIPHVSSLLNSDFDQ 386
Cdd:PRK15182  308 KGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDAEEVRR------EYGIIPVSEVKSSHYDA 381


                  ..
gi 1276655780 387 VI 388
Cdd:PRK15182  382 II 383
UDPG_MGDP_dh_C smart00984
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ...
 317-421 1.63e-15

UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 214954 [Multi-domain]  Cd Length: 99  Bit Score: 71.77  E-value: 1.63e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780  317 ALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDsnveyarvhgankDYIESKIPHVSSLLNSDFDQVINDSDVIIL 396
Cdd:smart00984   1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYD-------------PYAMEEAREYGLTYVSDLEEALKGADAVVI 67

                           90       100
                   ....*....|....*....|....*....
gi 1276655780  397 GNRDERFRALA----NKTPEGKRVIDLVG 421
Cdd:smart00984  68 ATEHDEFRSLDpeelKDLMKKPVVVDGRN 96
UDPG_MGDP_dh_C pfam03720
UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose ...
 317-418 1.04e-12

UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 427462 [Multi-domain]  Cd Length: 103  Bit Score: 64.13  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780 317 ALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEyarvhganKDYIESKIPHVSSLlnSDFDQVINDSDVIIL 396
Cdd:pfam03720   1 AVLGLAFKPNTDDLRESPALDIIELLLEEGAEVKVYDPYVP--------EEAIEALGDGVTLV--DDLEEALKGADAIVI 70

                          90       100
                  ....*....|....*....|....*.
gi 1276655780 397 GNRDERFRAL----ANKTPEGKRVID 418
Cdd:pfam03720  71 LTDHDEFKSLdwekLKKLMKPPVVFD 96
TyrA COG0287
Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is ...
 1-120 3.60e-04

Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440056 [Multi-domain]  Cd Length: 278  Bit Score: 42.04  E-value: 3.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARG--HDVVGVDISstkidlinngkspivEPGLEELLQKGLATgklRGTTDFAEAIRATD 78
Cdd:COG0287     2 MRIAIIGLGLIGGSLALALKRAGlaHEVVGVDRS---------------PETLERALELGVID---RAATDLEEAVADAD 63

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1276655780  79 LSMICVgtPskkngdleLDYIESVCREIGYVLRDkntrHTIV 120
Cdd:COG0287    64 LVVLAV--P--------VGATIEVLAELAPHLKP----GAIV 91
PRK08229 PRK08229
2-dehydropantoate 2-reductase; Provisional
 1-134 1.40e-03

2-dehydropantoate 2-reductase; Provisional


Pssm-ID: 236193 [Multi-domain]  Cd Length: 341  Bit Score: 40.76  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVdisstkidlinnGKSPIvepgLEELLQKGLATGKLRG------------TT 68
Cdd:PRK08229    3 ARICVLGAGSIGCYLGGRLAAAGADVTLI------------GRARI----GDELRAHGLTLTDYRGrdvrvppsaiafST 66

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1276655780  69 DFAEAIRAtDLSMICVGTPSKKNGDLELdyiESVCREIGYVLRDKN-TRHTIVVRS-----TVLPGTVA-NVV 134
Cdd:PRK08229   67 DPAALATA-DLVLVTVKSAATADAAAAL---AGHARPGAVVVSFQNgVRNADVLRAalpgaTVLAGMVPfNVI 135
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 1-121 3.14e-03

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 39.45  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTkIDLINngkspivEPGLE-ELLQKGLATGKLRGTTDfAEAIRATDL 79
Cdd:COG1893     1 MKIAILGAGAIGGLLGARLARAGHDVTLVARGAH-AEALR-------ENGLRlESPDGDRTTVPVPAVTD-PEELGPADL 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1276655780  80 SMICVgtpskKNGDLeldyiESVCREigyvLRDKNTRHTIVV 121
Cdd:COG1893    72 VLVAV-----KAYDL-----EAAAEA----LAPLLGPDTVVL 99
MmsB COG2084
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ...
 1-130 3.83e-03

3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];


Pssm-ID: 441687 [Multi-domain]  Cd Length: 285  Bit Score: 38.94  E-value: 3.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKidlinngkspivepgLEELLQKGlatgkLRGTTDFAEAIRATDLS 80
Cdd:COG2084     2 MKVGFIGLGAMGAPMARNLLKAGHEVTVWNRTPAK---------------AEALVAAG-----ARVAASPAEAAAAADVV 61

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1276655780  81 MICVGTPskkngdlelDYIESVCREIGYVLRDKNTRHTIVVRSTVLPGTV 130
Cdd:COG2084    62 ITMLPDD---------AAVEEVLLGEDGLLAALRPGAVVVDMSTISPETA 102
PRK06522 PRK06522
2-dehydropantoate 2-reductase; Reviewed
 1-84 4.49e-03

2-dehydropantoate 2-reductase; Reviewed


Pssm-ID: 235821 [Multi-domain]  Cd Length: 304  Bit Score: 39.06  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINngkspivEPGLEelLQKGLATGKLRGTTDFAEAIRAtDLS 80
Cdd:PRK06522    1 MKIAILGAGAIGGLFGAALAQAGHDVTLVARRGAHLDALN-------ENGLR--LEDGEITVPVLAADDPAELGPQ-DLV 70


                  ....
gi 1276655780  81 MICV 84
Cdd:PRK06522   71 ILAV 74
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 1-48 6.38e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 38.51  E-value: 6.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1276655780   1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVE 48
Cdd:COG0569    96 MHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIV 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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