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Conserved domains on  [gi|1162443571|ref|XP_008666211|]
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uncharacterized protein LOC103644833 isoform X1 [Zea mays]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 581124)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  8882580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT1 super family cl23759
GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription ...
 104-197 1.35e-18

GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription factors. GT-1 binds the GT cis-element of rbcS-3A, a light-induced gene, as a dimer. Arabidopsis GT-1 is a trans-activator and acts in the stabilization of components of the transcription pre-initiation complex comprised of TFIIA-TBP-TATA. The isolated GT-1 DNA-binding domain is sufficient to bind DNA. This region closely resembles the myb domain, but with longer helices. It has been proposed that GT-1 may respond to light signals via calcium-dependent phosphorylation to create a light-modulated molecular switch. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.


The actual alignment was detected with superfamily member pfam12776:

Pssm-ID: 474047  Cd Length: 96  Bit Score: 80.44  E-value: 1.35e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162443571 104 WNPGLERSLVDILHEFKESGYRG-DNGWNSEGWNRMVKEFhVRNKYVSFTKSQIQDKEGQLKRDYKMLKAAKQQSGSTWN 182
Cdd:pfam12776   2 WTPEMDRYFVDLLLEQVNRGNRIeGHTFNKEAWKEILAAF-NAKTGAQYTKDQLKNRWDNLRKQYRLWKRLLERPGFSWD 80

                          90
                  ....*....|....*
gi 1162443571 183 EKRNMVEGPPALWEN 197
Cdd:pfam12776  81 PTTRMVTATDEVWDN 95
 
Name Accession Description Interval E-value
Myb_DNA-bind_3 pfam12776
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 104-197 1.35e-18

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 432776  Cd Length: 96  Bit Score: 80.44  E-value: 1.35e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162443571 104 WNPGLERSLVDILHEFKESGYRG-DNGWNSEGWNRMVKEFhVRNKYVSFTKSQIQDKEGQLKRDYKMLKAAKQQSGSTWN 182
Cdd:pfam12776   2 WTPEMDRYFVDLLLEQVNRGNRIeGHTFNKEAWKEILAAF-NAKTGAQYTKDQLKNRWDNLRKQYRLWKRLLERPGFSWD 80

                          90
                  ....*....|....*
gi 1162443571 183 EKRNMVEGPPALWEN 197
Cdd:pfam12776  81 PTTRMVTATDEVWDN 95
 
Name Accession Description Interval E-value
Myb_DNA-bind_3 pfam12776
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 104-197 1.35e-18

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 432776  Cd Length: 96  Bit Score: 80.44  E-value: 1.35e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162443571 104 WNPGLERSLVDILHEFKESGYRG-DNGWNSEGWNRMVKEFhVRNKYVSFTKSQIQDKEGQLKRDYKMLKAAKQQSGSTWN 182
Cdd:pfam12776   2 WTPEMDRYFVDLLLEQVNRGNRIeGHTFNKEAWKEILAAF-NAKTGAQYTKDQLKNRWDNLRKQYRLWKRLLERPGFSWD 80

                          90
                  ....*....|....*
gi 1162443571 183 EKRNMVEGPPALWEN 197
Cdd:pfam12776  81 PTTRMVTATDEVWDN 95
Myb_DNA-bind_4 pfam13837
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ...
 101-181 5.45e-04

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 463994  Cd Length: 84  Bit Score: 38.79  E-value: 5.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162443571 101 RADWNPGLERSLVDILHEFKESGYRGDNGWNSEGWNRMVKEFHVRNkyvsFTKS--QIQDKEGQLKRDYKMLKAAKQQSG 178
Cdd:pfam13837   1 RNKWTEEETLALIEIWGERLELRFQESKKRNKKLWEEIAEKMAELG----YNRSpeQCKEKWENLKKKYRKEKEGNNGSG 76


                  ...
gi 1162443571 179 STW 181
Cdd:pfam13837  77 SSW 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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