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Conserved domains on  [gi|1002623822|gb|AMN14476|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Brachiones przewalskii]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 5.84e-68

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 204.27  E-value: 5.84e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYSVDEMGIMGEEGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00109  162 FIGVFVIIEITR 173
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 5.84e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 204.27  E-value: 5.84e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYSVDEMGIMGEEGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00109  162 FIGVFVIIEITR 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 9.02e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.35  E-value: 9.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  17 VGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPETWGSDWLTFICLVSGL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002623822  97 FMELMFIYLVGSYFMEDFGVEVYGMDNwvvySVDEMGImgeegagvaALYSCAAWVMVVAGWSLFVGVLVIIEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 5.84e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 204.27  E-value: 5.84e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYSVDEMGIMGEEGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00109  162 FIGVFVIIEITR 173
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 7.36e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 104.45  E-value: 7.36e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGsdwltficlvSGLFMELMFIYLVG-SYFMEDFGVEVYGMDNWVVYSVDEMGIMGEEGAGVAALYSCAAWVMVVAGWS 159
Cdd:MTH00138   81 SWG----------SWSVLGYVVGYLVGvVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                         170
                  ....*....|...
gi 1002623822 160 LFVGVLVIIEITR 172
Cdd:MTH00138  151 LLLTLFVVLELTR 163
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 2.84e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 92.60  E-value: 2.84e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGSdWLTFICLVSGLFMELMFIYLVGSYFmedfgvevyGMDNWVVYSVDEMGIMGEEGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00065   81 AWGS-WSVLVYVLFYLLLLIVGYILFGCNF---------SLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00065  151 LLTLFVVLEVTR 162
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 3.65e-21

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 84.80  E-value: 3.65e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYSVDemgimgeeGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLD--------FSGVSLFYSSGGGGLLVCGWGL 152

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00115  153 LLTLFVVLELVR 164
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 7.97e-14

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 65.40  E-value: 7.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFLAGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TWGsdwltficlvSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYsvdeMGIMGEEGAGVAALYSCAAWVMVVAGWSL 160
Cdd:MTH00214   81 SWG----------GWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGV----DEANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                         170
                  ....*....|..
gi 1002623822 161 FVGVLVIIEITR 172
Cdd:MTH00214  147 FLVLFVVLELVR 158
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-172 1.54e-09

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 53.76  E-value: 1.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   1 MTNYMFVLSLLFlaGCVGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPE 80
Cdd:MTH00045    1 MVFYLFLILMLF--GSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  81 TwgSDWLTFICLVsglfmeLMFIYLVGSYFmedfgvevygmDNWVVYSVDEMGIMGEEG-AGVAALYSCAAWVMVVAGWS 159
Cdd:MTH00045   79 V--SNLGEVLVLS------LLLSLWVFISF-----------DNFLELSNNNWSLVSLSDlVGSSELYNSGGLYLLLGGFI 139

                         170
                  ....*....|...
gi 1002623822 160 LFVGVLVIIEITR 172
Cdd:MTH00045  140 LLVALVVALVISF 152
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 9.02e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.35  E-value: 9.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822  17 VGLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPETWGSDWLTFICLVSGL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002623822  97 FMELMFIYLVGSYFMEDFGVEVYGMDNwvvySVDEMGImgeegagvaALYSCAAWVMVVAGWSLFVGVLVIIEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 3-121 3.44e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 41.92  E-value: 3.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   3 NYMFVLSLLFLAGCVgLALKPSPIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYP-ET 81
Cdd:MTH00212    2 LLSLLLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEHLfFK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1002623822  82 WGSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGM 121
Cdd:MTH00212   81 KYFKGFGMILISLNLYLLLMTLGSSNFSPMLNLKLELNVS 120
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 5-128 4.40e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 36.02  E-value: 4.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002623822   5 MFVLSLLFLAGCVGLALKPS--PIYGGVVLVVSGCLGCLTVLGYGGPFLGLAVFLIYLGGMTVVFGYTTAMASEEYPETW 82
Cdd:MTH00152    1 MSLMILLSVCFSLFLLLPLSkqPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1002623822  83 GSDWLTFICLVSGLFMELMFIYLVGSYFMEDFGVEVYGMDNWVVYS 128
Cdd:MTH00152   81 FKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSSGSLSFGG 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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