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Conserved domains on  [gi|2193134192|ref|WP_238318211|]
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polyprenyl diphosphate synthase [Chlamydia ibidis]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 613)

undecaprenyl diphosphate synthase family protein such as isoprenyl transferase; belongs to the cis (Z)-isoprenyl diphosphate synthases (cis-IPPS), which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates, where a few family members can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP.

EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0046872
PubMed:  12135472

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS super family cl00230
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 1-225 3.21e-141

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


The actual alignment was detected with superfamily member PRK14840:

Pssm-ID: 469674  Cd Length: 250  Bit Score: 394.98  E-value: 3.21e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14840   26 MDGNRRWYRKHEQFCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNSQLDSQLPYL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14840  106 HENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDDISEELISSY 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14840  186 LDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
 
Name Accession Description Interval E-value
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 1-225 3.21e-141

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 394.98  E-value: 3.21e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14840   26 MDGNRRWYRKHEQFCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNSQLDSQLPYL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14840  106 HENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDDISEELISSY 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14840  186 LDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
1-225 1.65e-113

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 324.70  E-value: 1.65e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:COG0020    23 MDGNGRWAKKRGLPR----IEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLRRELDEL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:COG0020    99 HKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDEETISRY 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:COG0020   179 LYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGG 243
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 1-218 2.15e-107

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 307.76  E-value: 2.15e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:cd00475     6 MDGNRRWAKKRGLPR----TEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:cd00475    82 HKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISKH 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQ 218
Cdd:cd00475   162 LYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 1-222 4.00e-104

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 299.67  E-value: 4.00e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQ-LDIQLPY 79
Cdd:pfam01255   2 MDGNRRWAKKRGLPR----EAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEyLRRELPE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  80 LIENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDllNRTISLEDVSESLVNS 159
Cdd:pfam01255  78 LHKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKE--GKKLDPEDIDEELISS 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2193134192 160 YLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRR 222
Cdd:pfam01255 156 HLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERR 218
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 1-224 5.43e-79

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 236.15  E-value: 5.43e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLeyssGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:TIGR00055   7 MDGNGRWAKKKGKPRAY----GHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVKEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:TIGR00055  83 HRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLNKH 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:TIGR00055 163 LYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 1-225 3.21e-141

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 394.98  E-value: 3.21e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14840   26 MDGNRRWYRKHEQFCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNSQLDSQLPYL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14840  106 HENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDDISEELISSY 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14840  186 LDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
1-225 1.65e-113

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 324.70  E-value: 1.65e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:COG0020    23 MDGNGRWAKKRGLPR----IEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLRRELDEL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:COG0020    99 HKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDEETISRY 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:COG0020   179 LYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGG 243
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 1-218 2.15e-107

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 307.76  E-value: 2.15e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:cd00475     6 MDGNRRWAKKRGLPR----TEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:cd00475    82 HKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISKH 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQ 218
Cdd:cd00475   162 LYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 1-222 4.00e-104

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 299.67  E-value: 4.00e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQ-LDIQLPY 79
Cdd:pfam01255   2 MDGNRRWAKKRGLPR----EAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEyLRRELPE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  80 LIENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDllNRTISLEDVSESLVNS 159
Cdd:pfam01255  78 LHKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKE--GKKLDPEDIDEELISS 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2193134192 160 YLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRR 222
Cdd:pfam01255 156 HLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERR 218
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 1-224 1.69e-94

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 276.37  E-value: 1.69e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14830   30 MDGNGRWAKKRMLPR----IAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFLDKFVPEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14830  106 IENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPEDITEELISNY 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK14830  186 LMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFG 249
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 1-224 5.43e-79

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 236.15  E-value: 5.43e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLeyssGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:TIGR00055   7 MDGNGRWAKKKGKPRAY----GHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVKEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:TIGR00055  83 HRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLNKH 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:TIGR00055 163 LYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 1-225 6.51e-77

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 231.88  E-value: 6.51e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14836   22 MDGNGRWAKRRGKPR----VEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKALDREVDKL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14836   98 HRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEIDEALLAQH 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14836  178 LALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGK 242
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 1-225 1.15e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 223.67  E-value: 1.15e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14831   28 MDGNGRWAKRRGLPR----IMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVLRRELEEL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14831  104 MEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEIDENLFESE 183

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14831  184 LYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
1-224 1.35e-70

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 215.45  E-value: 1.35e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKpahlEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14833   12 MDGNGRWAKLRGK----ARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLKDERSTY 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLhLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14833   88 LENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKL-LESPPSHIGELESLEEEISNC 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK14833  167 LDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14838 PRK14838
isoprenyl transferase;
1-225 2.17e-66

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 204.72  E-value: 2.17e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLpyL 80
Cdd:PRK14838   18 MDGNGRWAKERGKER----SFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSIEEET--F 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14838   92 MKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEITEESISEH 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14838  172 LTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGK 236
PRK14834 PRK14834
isoprenyl transferase;
1-225 3.10e-66

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 204.60  E-value: 3.10e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQqkpaHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14834   22 MDGNGRWAKAR----GLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRDLAEL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14834   98 HRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDAETISAN 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRR-GGR 225
Cdd:PRK14834  178 LDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRfGGL 243
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
1-224 8.76e-63

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 195.20  E-value: 8.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAHLeyssGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK10240    1 MDGNGRWAKKQGKIRAF----GHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK10240   77 HRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQH 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK10240  157 ICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFG 220
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 1-225 8.63e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 190.98  E-value: 8.63e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14832   26 MDGNGRWATSQGLPR----IAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLRRELAQM 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14832  102 HREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEQLVEQH 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14832  182 LYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 1-224 1.25e-56

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 179.80  E-value: 1.25e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14841   11 MDGNGRWAKKRGLPR----IKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDREMELL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDL-LNRTISLedvSESLVNS 159
Cdd:PRK14841   87 RRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVsQGKKIEL---TEETFRQ 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 160 YLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK14841  164 YLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 1-224 5.15e-54

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 173.25  E-value: 5.15e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14842   16 MDGNGRWAESQGKKR----SEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFIETRLDTI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLED-VSESLVNS 159
Cdd:PRK14842   92 HARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTLEKpLKEKEFEK 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 160 YLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK14842  172 FLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 1-225 4.18e-50

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 163.07  E-value: 4.18e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQkpahLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14837   14 MDGNRRWALKKG----LSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLSSEFNFY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLhldlLNRTISLEDVSESLVNSY 160
Cdd:PRK14837   90 KKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKF----LSSGLDLETLNENVFSKF 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14837  166 LDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFGR 230
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
1-224 4.33e-50

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 163.00  E-value: 4.33e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQKPAhleySSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14839   17 MDGNGRWATARGLPR----LAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETERL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRA-FKKLHLDLLNRtislEDVSESLvns 159
Cdd:PRK14839   93 ARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAaAKALGPEGLSR----EAFSDLL--- 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 160 yldTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGG 224
Cdd:PRK14839  166 ---TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 1-225 8.37e-50

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 162.65  E-value: 8.37e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQkpahLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14829   22 MDGNGRWATQRG----LKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIHRRREQM 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14829   98 DEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGDRVTEKMISDH 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14829  178 LYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGG 242
PRK14835 PRK14835
isoprenyl transferase;
1-225 8.91e-48

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 158.47  E-value: 8.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWykqqQKPAHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLF---STQLDIQl 77
Cdd:PRK14835   49 LDGNRRF----ARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFereARRMAVD- 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  78 PYLIENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESL- 156
Cdd:PRK14835  124 PRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSPEEVAAELt 203

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2193134192 157 ---VNSYLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14835  204 pehISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 1-225 2.22e-42

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 143.73  E-value: 2.22e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKqqqKPAHLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPyl 80
Cdd:PRK14828   34 VDGNRRWAR---KAGFTDVSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIEDVVRQLAP-- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 iENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSES----L 156
Cdd:PRK14828  109 -DGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSIDELAESvtvdA 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2193134192 157 VNSYLDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFtgRH---LRdAITAYQQRSRRGGR 225
Cdd:PRK14828  188 ISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAF--RKvdfLR-ALRDYSQRERRFGK 256
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 1-225 2.26e-41

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 142.40  E-value: 2.26e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQkpahLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQLDIQLPYL 80
Cdd:PRK14827   75 MDGNGRWATQRG----LARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVRRRRDNL 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  81 IENQIRLRCIGNLSKLPSYIQDKLNKVINVTNTFSRMDLVLAINYGGKDELIRAFKKLHLDLLNRTISLEDVSESLVNSY 160
Cdd:PRK14827  151 NKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERITESTIARH 230

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2193134192 161 LDTSEVGDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTGRHLRDAITAYQQRSRRGGR 225
Cdd:PRK14827  231 LQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 1-204 2.14e-22

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 92.75  E-value: 2.14e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192   1 MDGNRRWYKQQQkpahLEYSSGHYYGAKVLPRIVQSALTYGVEVLTLFAFSTENFLRSQDEVSELFSLFSTQL---DIQL 77
Cdd:PTZ00349   27 MDGNRRFAKEKG----LHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLNLLILineDFFF 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192  78 PYLIENQIRLRCIGNLsklpSYIQDKLNKVI----NVTNTFSRMDLVLAINYGGKDEL----------IRAFKKL----- 138
Cdd:PTZ00349  103 KFIKDNKIKIKIIGNL----SYINDAYRKIIhdieEKTENFDNILLNIFFSYTSRNEMslckfnpnlyFDTYKNLleekk 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193134192 139 ------------------------HLDLLNRTISLEDVSESL---------------------VNSY--LDTSEVGDPDL 171
Cdd:PTZ00349  179 ilcgsniltdpikegtfaipddedECDYLDHELENERIDLDLkfdgdcicgeksflneeqieiVNYHkkLLTSDLPPPNI 258

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2193134192 172 LIRTGGEMRVSNFLLWQIA-YTELYVTDVLWPDF 204
Cdd:PTZ00349  259 LIRTSGEKRLSDFMLYQISeFTEIYFINEYWPIF 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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