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Conserved domains on  [gi|2099545785|gb|UBI29253|]
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HNH endonuclease (plasmid) [Burkholderia vietnamiensis]

Protein Classification

HNH endonuclease( domain architecture ID 11465816)

HNH endonuclease similar to Haemophilus parahaemolyticus type II restriction enzyme HphI, which recognizes the double-stranded sequences, GGTGA and TCACC, and performs endonucleolytic cleavage of DNA to give specific double-stranded fragments

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3440 COG3440
Predicted restriction endonuclease [Defense mechanisms];
376-480 7.99e-21

Predicted restriction endonuclease [Defense mechanisms];


:

Pssm-ID: 442665  Cd Length: 150  Bit Score: 88.90  E-value: 7.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2099545785 376 DERVARYMSVEVRQEQPAFRKAVFEAYGRRCAISGCDIPEVLEAAHLRGRDWRAGHNAAADGILLRRDLHTLYDRELLEL 455
Cdd:COG3440    17 LERTERERLVKRRVRQGAFRKAVLEAYDGRCAVTGLDIPPLLEAAHIKPWSDHGGRDDVSNGLLLCPNHHALFDRGLITI 96

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2099545785 456 S-DGVARFSP------LVAHHYAHLDGAPVAV 480
Cdd:COG3440    97 DdDYRILVSPrlkeesDLIRELKELHGRKLRL 128
 
Name Accession Description Interval E-value
COG3440 COG3440
Predicted restriction endonuclease [Defense mechanisms];
376-480 7.99e-21

Predicted restriction endonuclease [Defense mechanisms];


Pssm-ID: 442665  Cd Length: 150  Bit Score: 88.90  E-value: 7.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2099545785 376 DERVARYMSVEVRQEQPAFRKAVFEAYGRRCAISGCDIPEVLEAAHLRGRDWRAGHNAAADGILLRRDLHTLYDRELLEL 455
Cdd:COG3440    17 LERTERERLVKRRVRQGAFRKAVLEAYDGRCAVTGLDIPPLLEAAHIKPWSDHGGRDDVSNGLLLCPNHHALFDRGLITI 96

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2099545785 456 S-DGVARFSP------LVAHHYAHLDGAPVAV 480
Cdd:COG3440    97 DdDYRILVSPrlkeesDLIRELKELHGRKLRL 128
HNH_2 pfam13391
HNH endonuclease;
406-453 2.05e-08

HNH endonuclease;


Pssm-ID: 433168  Cd Length: 66  Bit Score: 50.86  E-value: 2.05e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2099545785 406 CAISGCDIPEVLEAAHL---------RGRDWRAGHNAAAD------GILLRRDLHTLYDRELL 453
Cdd:pfam13391   1 CVITGIDAPGLLEAAHIfpwslslgdRRFSAIRLGEGPSGidsprnGLLLRPDLHRLFDRGLF 63
 
Name Accession Description Interval E-value
COG3440 COG3440
Predicted restriction endonuclease [Defense mechanisms];
376-480 7.99e-21

Predicted restriction endonuclease [Defense mechanisms];


Pssm-ID: 442665  Cd Length: 150  Bit Score: 88.90  E-value: 7.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2099545785 376 DERVARYMSVEVRQEQPAFRKAVFEAYGRRCAISGCDIPEVLEAAHLRGRDWRAGHNAAADGILLRRDLHTLYDRELLEL 455
Cdd:COG3440    17 LERTERERLVKRRVRQGAFRKAVLEAYDGRCAVTGLDIPPLLEAAHIKPWSDHGGRDDVSNGLLLCPNHHALFDRGLITI 96

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2099545785 456 S-DGVARFSP------LVAHHYAHLDGAPVAV 480
Cdd:COG3440    97 DdDYRILVSPrlkeesDLIRELKELHGRKLRL 128
HNH_2 pfam13391
HNH endonuclease;
406-453 2.05e-08

HNH endonuclease;


Pssm-ID: 433168  Cd Length: 66  Bit Score: 50.86  E-value: 2.05e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2099545785 406 CAISGCDIPEVLEAAHL---------RGRDWRAGHNAAAD------GILLRRDLHTLYDRELL 453
Cdd:pfam13391   1 CVITGIDAPGLLEAAHIfpwslslgdRRFSAIRLGEGPSGidsprnGLLLRPDLHRLFDRGLF 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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