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Conserved domains on  [gi|13878553|sp|Q9H0B6|]
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RecName: Full=Kinesin light chain 2; Short=KLC 2

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 12138572)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
195-434 6.67e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 109.71  E-value: 6.67e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG0457   5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 354
Cdd:COG0457  72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 355 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 434
Cdd:COG0457 140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
Crescentin super family cl41192
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 26-132 1.07e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


The actual alignment was detected with superfamily member pfam19220:

Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553    26 QGLETLRGEHRALLAPLVAPEAGEAEpgSQERCILLRRSLEAIELGLGEAQVILA-LSSHLGAVESEKQKLRAQVRRLVQ 104
Cdd:pfam19220  62 AAYGKLRRELAGLTRRLSAAEGELEE--LVARLAKLEAALREAEAAKEELRIELRdKTAQAEALERQLAAETEQNRALEE 139

                          90       100
                  ....*....|....*....|....*...
gi 13878553   105 ENQWLREELAGTQQKLQRSEQAVAQLEE 132
Cdd:pfam19220 140 ENKALREEAQAAEKALQRAEGELATARE 167
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
195-434 6.67e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 109.71  E-value: 6.67e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG0457   5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 354
Cdd:COG0457  72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 355 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 434
Cdd:COG0457 140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 195-388 3.92e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.90  E-value: 3.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  275 -GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 353
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 13878553  354 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 188-419 1.06e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 87.28  E-value: 1.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  188 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDA 266
Cdd:NF040586 595 VLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREV 673

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  267 LAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP---DVAKQLSN-LALLCQNQGKAEE 342
Cdd:NF040586 674 LDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLANdLAALGDLDAALGE 753

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553  343 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKPIWMHAEERE 419
Cdd:NF040586 754 EALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR-----LRRVLGPDHPDTVAAREGR 825
TPR_12 pfam13424
Tetratricopeptide repeat;
238-314 3.05e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 76.66  E-value: 3.05e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553   238 DVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 211-484 4.43e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 85.36  E-value: 4.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI--REKTLGKDHPAVAATLNNL 288
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  289 AVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGkaeeveyYYRRALEI----YATR---LGPD 361
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLG-------DYREALELdrevLRRRrrvLGPD 557

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  362 DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEkefgSVNGDNKPIWMHAE-----------EREESKDKRRDSap 430
Cdd:NF040586 558 HPRTLLSANNLARDLRELGRYAEALDLLEEALERYRE----VLGGPDHPDTLRAAkslavalrragRLEEALELAEDT-- 631

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553  431 YGEYGSWYKAckvDSPTVNTTLRSLGALYRRQGKLEAAHTL-EDCASRNRKQ-GLD 484
Cdd:NF040586 632 YERYRRRFGP---DHPDTLAAALSLANDLRALGDADEARELaREVLDRYRRVlGED 684
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 197-410 4.94e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 81.89  E-value: 4.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  197 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 354
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553  355 ATRL-GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKP 410
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-----YRRRFGPDHP 644
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 188-385 4.69e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 78.81  E-value: 4.69e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  188 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDA 266
Cdd:NF040586 552 RVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDT 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  267 LAIREKTLGKDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEY 345
Cdd:NF040586 632 YERYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARE 710

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 13878553  346 YYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA 385
Cdd:NF040586 711 LAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAA 750
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 196-390 2.54e-10

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 60.81  E-value: 2.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   196 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 275
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   276 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 355
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 13878553   356 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYK 390
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 282-314 2.13e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 2.13e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 13878553    282 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 26-132 1.07e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553    26 QGLETLRGEHRALLAPLVAPEAGEAEpgSQERCILLRRSLEAIELGLGEAQVILA-LSSHLGAVESEKQKLRAQVRRLVQ 104
Cdd:pfam19220  62 AAYGKLRRELAGLTRRLSAAEGELEE--LVARLAKLEAALREAEAAKEELRIELRdKTAQAEALERQLAAETEQNRALEE 139

                          90       100
                  ....*....|....*....|....*...
gi 13878553   105 ENQWLREELAGTQQKLQRSEQAVAQLEE 132
Cdd:pfam19220 140 ENKALREEAQAAEKALQRAEGELATARE 167
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 291-471 2.98e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.67  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  291 LYgKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEV---------------------EY---- 345
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  346 ------------YYRRALEI-------YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNG 406
Cdd:NF040586 481 agglgadlralgRFREALELdeetlerHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-----RRRVLG 555

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553  407 DNKP----IWMH-------AEEREESKDKRRDSAPYGEygswYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 471
Cdd:NF040586 556 PDHPrtllSANNlardlreLGRYAEALDLLEEALERYR----EVLGGPDHPDTLRAAKSLAVALRRAGRLEEALEL 627
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
195-434 6.67e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 109.71  E-value: 6.67e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG0457   5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 354
Cdd:COG0457  72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 355 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 434
Cdd:COG0457 140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 195-388 3.92e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.90  E-value: 3.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  275 -GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 353
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 13878553  354 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 193-396 4.39e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.21  E-value: 4.39e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 193 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrek 272
Cdd:COG3914  33 EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAA--AAALLLLAALLELAALLLQALGRYEEALALYRRALAL--- 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 273 tlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALE 352
Cdd:COG3914 108 -----NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 13878553 353 IyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 396
Cdd:COG3914 175 L--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 188-419 1.06e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 87.28  E-value: 1.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  188 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDA 266
Cdd:NF040586 595 VLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREV 673

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  267 LAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP---DVAKQLSN-LALLCQNQGKAEE 342
Cdd:NF040586 674 LDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLANdLAALGDLDAALGE 753

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553  343 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKPIWMHAEERE 419
Cdd:NF040586 754 EALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR-----LRRVLGPDHPDTVAAREGR 825
TPR_12 pfam13424
Tetratricopeptide repeat;
238-314 3.05e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 76.66  E-value: 3.05e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553   238 DVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 211-484 4.43e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 85.36  E-value: 4.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI--REKTLGKDHPAVAATLNNL 288
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  289 AVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGkaeeveyYYRRALEI----YATR---LGPD 361
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLG-------DYREALELdrevLRRRrrvLGPD 557

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  362 DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEkefgSVNGDNKPIWMHAE-----------EREESKDKRRDSap 430
Cdd:NF040586 558 HPRTLLSANNLARDLRELGRYAEALDLLEEALERYRE----VLGGPDHPDTLRAAkslavalrragRLEEALELAEDT-- 631

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553  431 YGEYGSWYKAckvDSPTVNTTLRSLGALYRRQGKLEAAHTL-EDCASRNRKQ-GLD 484
Cdd:NF040586 632 YERYRRRFGP---DHPDTLAAALSLANDLRALGDADEARELaREVLDRYRRVlGED 684
TPR_12 pfam13424
Tetratricopeptide repeat;
281-354 3.70e-16

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 73.58  E-value: 3.70e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13878553   281 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 354
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 197-410 4.94e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 81.89  E-value: 4.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  197 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 354
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 13878553  355 ATRL-GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKP 410
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-----YRRRFGPDHP 644
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 195-398 6.96e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.23  E-value: 6.96e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG2956  73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLE--------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL----- 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 354
Cdd:COG2956 140 ---GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ- 207

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 13878553 355 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:COG2956 208 -------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 188-385 4.69e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 78.81  E-value: 4.69e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  188 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDA 266
Cdd:NF040586 552 RVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDT 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  267 LAIREKTLGKDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEY 345
Cdd:NF040586 632 YERYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARE 710

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 13878553  346 YYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA 385
Cdd:NF040586 711 LAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAA 750
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 208-398 1.28e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 1.28e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 208 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTlgkdhpavAATLNN 287
Cdd:COG2956  52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD--------AEALRL 115

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 288 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAK 367
Cdd:COG2956 116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179

                       170       180       190
                ....*....|....*....|....*....|.
gi 13878553 368 TKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:COG2956 180 ALLLLAELYLEQGDYEEAIAALERALEQDPD 210
TPR_12 pfam13424
Tetratricopeptide repeat;
197-272 2.03e-14

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 68.57  E-value: 2.03e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553   197 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREK 272
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 207-478 6.69e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 6.69e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 207 QYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTlgkdhpavAATLN 286
Cdd:COG2956  17 NYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR--------AEALL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 287 NLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKaeeveyyYRRALEiYATRLGPDDPNVA 366
Cdd:COG2956  81 ELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRLLAEIYEQEGD-------WEKAIE-VLERLLKLGPENA 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 367 KTKNNLASCYLKQGKYQDAETLYKEILtrahekefgSVNGDNKPIWMHAEEREESKDKrrdsapYGEYGSWYKACKVDSP 446
Cdd:COG2956 145 HAYCELAELYLEQGDYDEAIEALEKAL---------KLDPDCARALLLLAELYLEQGD------YEEAIAALERALEQDP 209

                       250       260       270
                ....*....|....*....|....*....|...
gi 13878553 447 TVNTTLRSLGALYRRQGKLEAA-HTLEDCASRN 478
Cdd:COG2956 210 DYLPALPRLAELYEKLGDPEEAlELLRKALELD 242
TPR_12 pfam13424
Tetratricopeptide repeat;
322-396 1.11e-12

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 63.56  E-value: 1.11e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 13878553   322 DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 396
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
TPR_10 pfam13374
Tetratricopeptide repeat;
281-322 1.51e-12

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 62.13  E-value: 1.51e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 13878553   281 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 322
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 207-398 6.10e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 6.10e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 207 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEA-AHLLNDALAIREKTLGKDHPAVAATL 285
Cdd:COG3914   2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAaAAALLALAAGEAAAAAAALLLLAALL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 286 NNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNV 365
Cdd:COG3914  82 ELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDF 145

                       170       180       190
                ....*....|....*....|....*....|...
gi 13878553 366 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:COG3914 146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPD 178
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 196-355 7.13e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 7.13e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 196 ARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 275
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 276 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKvlgkfHPDVakqLSNLALLCQNQGKAEEVEYYYRRALEIYA 355
Cdd:COG4783  68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPE-----HPEA---YLRLARAYRALGRPDEAIAALEKALELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 246-398 2.63e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.75  E-value: 2.63e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 246 LALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAK 325
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 13878553 326 QLSNLALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAktkNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:COG4783  74 ARLNLGLALLKAGDYDEALALLEKALKLD-----PEHPEAY---LRLARAYRALGRPDEAIAALEKALELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 245-468 6.81e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.21  E-value: 6.81e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 245 ILALVYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVA 324
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 325 KQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTrahekefgsV 404
Cdd:COG2956  77 EALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK---------L 139

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 13878553 405 NGDNKPIWMH-AEEREESKDKrrDSApygeYGSWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 468
Cdd:COG2956 140 GPENAHAYCElAELYLEQGDY--DEA----IEALEKALKLD-PDCARALLLLAELYLEQGDYEEA 197
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
195-355 1.99e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.56  E-value: 1.99e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRektl 274
Cdd:COG0457  73 PDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 354
Cdd:COG0457 141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216


                .
gi 13878553 355 A 355
Cdd:COG0457 217 A 217
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 196-390 2.54e-10

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 60.81  E-value: 2.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   196 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 275
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   276 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 355
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 13878553   356 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYK 390
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
249-358 3.27e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 3.27e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 249 VYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLcKRALEIrekvlgkfHPDVAKQLS 328
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                        90       100       110
                ....*....|....*....|....*....|
gi 13878553 329 NLALLCQNQGKAEEVEYYYRRALEIYATRL 358
Cdd:COG3063  64 NLAELLLELGDYDEALAYLERALELDPSAL 93
TPR_10 pfam13374
Tetratricopeptide repeat;
239-279 5.07e-10

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 54.82  E-value: 5.07e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 13878553   239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHP 279
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 234-396 5.30e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.43  E-value: 5.30e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 234 HDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIre 313
Cdd:COG5010   6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-- 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 314 kvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 393
Cdd:COG5010  84 ------DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                ...
gi 13878553 394 TRA 396
Cdd:COG5010 150 GTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
291-393 9.29e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.95  E-value: 9.29e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 291 LYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYyRRALEIyatrlgpdDPNVAKTKN 370
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                        90       100
                ....*....|....*....|...
gi 13878553 371 NLASCYLKQGKYQDAETLYKEIL 393
Cdd:COG3063  64 NLAELLLELGDYDEALAYLERAL 86
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
208-316 2.99e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 2.99e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 208 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLlNDALAIrektlgkdHPAVAATLNN 287
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64

                        90       100
                ....*....|....*....|....*....
gi 13878553 288 LAVLYGKRGKYKEAEPLCKRALEIREKVL 316
Cdd:COG3063  65 LAELLLELGDYDEALAYLERALELDPSAL 93
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 195-353 4.05e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 4.05e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG5010   9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 353
Cdd:COG5010  84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 280-396 5.41e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.81  E-value: 5.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 280 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYatrlg 359
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD----- 68

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 13878553 360 PDDPNVAktkNNLASCYLKQGKYQDAETLYKEILTRA 396
Cdd:COG4783  69 PDEPEAR---LNLGLALLKAGDYDEALALLEKALKLD 102
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
203-390 8.05e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.46  E-value: 8.05e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRektlgkdhPAVA 282
Cdd:COG4785  36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 283 ATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEiyatrLGPDD 362
Cdd:COG4785 108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKALE-----LDPND 174

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 13878553 363 P-------------NVAKTKNNL----ASCYLKQGKYQDAETLYK 390
Cdd:COG4785 175 PeralwlylaerklDPEKALALLledwATAYLLQGDTEEARELFK 219
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 276-396 1.08e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.86  E-value: 1.08e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 276 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 355
Cdd:COG4235  11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL-- 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 13878553 356 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 396
Cdd:COG4235  81 ------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 242-468 1.56e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.56e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 242 MLNILALVYRDQNKYKEAAHLLNDALAIREktlgkDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREkvLGKFHP 321
Cdd:COG3914   3 AAALLALAALAAAALLAAAAAAELALAAEL-----EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAA--AAAALL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 322 DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILtrahekef 401
Cdd:COG3914  76 LLAALLELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRAL-------- 139

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13878553 402 gSVNGDNKPIW-------MHAEEREESKDkrrdsapygeygSWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 468
Cdd:COG3914 140 -ALNPDFAEAYlnlgealRRLGRLEEAIA------------ALRRALELD-PDNAEALNNLGNALQDLGRLEEA 199
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
318-468 2.29e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.40  E-value: 2.29e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 318 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILtrah 397
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQAL---- 69

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 13878553 398 ekefgSVNGDNKPIWMHAEEREESKDKRRDSAPYgeygsWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 468
Cdd:COG0457  70 -----ELDPDDAEALNNLGLALQALGRYEEALED-----YDKALELD-PDDAEALYNLGLALLELGRYDEA 129
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 235-394 4.47e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.25  E-value: 4.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   235 DHPDVATMLNILALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNNLAVLYGKRgKYKEAEPLCKRALEIRek 314
Cdd:TIGR02917 765 THPNDAVLRTALAELYLAQKDYDKAIKHYQTVV--------KKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLA-- 833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   315 vlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlGPDDPNVaktKNNLASCYLKQGKYQDAETLYKEILT 394
Cdd:TIGR02917 834 ------PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI-----APEAAAI---RYHLALALLATGRKAEARKELDKLLN 899
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 223-373 1.47e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.47e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 223 QALEDLEKTSGHDHPDVATMLNiLALVYRDQNKYKEAAHLLNDALAIRektlgkdhPAVAATLNNLAVLYGKRGKYKEAE 302
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLL-LGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAE 71

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 13878553 303 PLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEiyatrLGPDDPNVAKTKNNLA 373
Cdd:COG4235  72 ELLERALAL--------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA-----LLPADAPARLLEASIA 129
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
195-352 7.18e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.68  E-value: 7.18e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRektl 274
Cdd:COG4785  70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALE--------LDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD---- 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 275 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK----------VLGKFHPDVAKQL--SNLALLCQNQGKAEE 342
Cdd:COG4785 138 ----PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNdperalwlylAERKLDPEKALALllEDWATAYLLQGDTEE 213

                       170
                ....*....|
gi 13878553 343 VEYYYRRALE 352
Cdd:COG4785 214 ARELFKLALA 223
TPR_10 pfam13374
Tetratricopeptide repeat;
198-238 1.26e-06

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 45.19  E-value: 1.26e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 13878553   198 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
246-428 1.70e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.53  E-value: 1.70e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 246 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAK 325
Cdd:COG4785  37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 326 QLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAEtlykEILTRAHEKefgSVN 405
Cdd:COG4785 109 AYNNRGLAYLLLGDYDAALEDFDRALEL--------DPDYAYAYLNRGIALYYLGRYELAI----ADLEKALEL---DPN 173

                       170       180
                ....*....|....*....|...
gi 13878553 406 GDNKPIWMHAEEREESKDKRRDS 428
Cdd:COG4785 174 DPERALWLYLAERKLDPEKALAL 196
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 208-398 4.31e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 4.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   208 YASQGRYEVAVPLCKQALEdLEKTSGhdhpdvATMLniLALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNN 287
Cdd:TIGR02917 713 YLRQKDYPAAIQAYRKALK-RAPSSQ------NAIK--LHRALLASGNTAEAVKTLEAWL--------KTHPNDAVLRTA 775

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   288 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQnQGKAEEVEYYYRRALEiyatrLGPDDPNVAK 367
Cdd:TIGR02917 776 LAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYL-ELKDPRALEYAERALK-----LAPNIPAILD 841

                         170       180       190
                  ....*....|....*....|....*....|.
gi 13878553   368 TknnLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:TIGR02917 842 T---LGWLLVEKGEADRALPLLRKAVNIAPE 869
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 195-311 7.30e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 7.30e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAirektL 274
Cdd:COG4783  35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALE--------LDPDEPEARLNLGLALLKAGDYDEALALLEKALK-----L 101

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 13878553 275 GKDHPAVaatLNNLAVLYGKRGKYKEAEPLCKRALEI 311
Cdd:COG4783 102 DPEHPEA---YLRLARAYRALGRPDEAIAALEKALEL 135
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 294-395 9.14e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 9.14e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 294 KRGKYKEAEPLCKRALeirekvlgKFHPD---VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAKTKN 370
Cdd:COG1729   5 KAGDYDEAIAAFKAFL--------KRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALL 71

                        90       100
                ....*....|....*....|....*
gi 13878553 371 NLASCYLKQGKYQDAETLYKEILTR 395
Cdd:COG1729  72 KLGLSYLELGDYDKARATLEELIKK 96
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 195-311 1.21e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 1.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLektsghdhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG4235  14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL----- 80

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 13878553 275 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 311
Cdd:COG4235  81 ---DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 222-396 1.33e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   222 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLgkdhPAVAAtlnnLAVLYGKRGKYKEA 301
Cdd:TIGR02917 107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL----YAKLG----LAQLALAENRFDEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   302 EPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGK 381
Cdd:TIGR02917 179 RALIDEVLTA--------DPGNVDALLLKGDLLLSLGNIELALAAYRKAIAL--------RPNNIAVLLALATILIEAGE 242

                         170
                  ....*....|....*
gi 13878553   382 YQDAETLYKEILTRA 396
Cdd:TIGR02917 243 FEEAEKHADALLKKA 257
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 195-312 1.57e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 1.57e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 274
Cdd:COG2956 175 PDCARALLLLAELYLEQGDYEEAIAALERALEQ--------DPDYLPALPRLAELYEKLGDPEEALELLRKALEL----- 241

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 13878553 275 gkdHPAVAAtLNNLAVLYGKRGKYKEAEPLCKRALEIR 312
Cdd:COG2956 242 ---DPSDDL-LLALADLLERKEGLEAALALLERQLRRH 275
TPR_1 pfam00515
Tetratricopeptide repeat;
282-314 4.42e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.87  E-value: 4.42e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 13878553   282 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 203-399 5.86e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDhPDVATMLNILALVYRDQNKykeaahlLNDALAIREKtLGKDHPAVA 282
Cdd:TIGR02917 395 ENAAARTQLGISKLSQGDPSEAIADLETAAQLD-PELGRADLLLILSYLRSGQ-------FDKALAAAKK-LEKKQPDNA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   283 ATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdD 362
Cdd:TIGR02917 466 SLHNLLGAIYLGKGDLAKAREAFEKALSI--------EPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTI--------D 529

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 13878553   363 PNVAKTKNNLASCYLKQGKYQDAetlyKEILTRAHEK 399
Cdd:TIGR02917 530 PKNLRAILALAGLYLRTGNEEEA----VAWLEKAAEL 562
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 195-356 7.11e-05

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 45.38  E-value: 7.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsgHDHPDVATM-LNILALVYRDQNKYKEAAHLLNDALAIREKT 273
Cdd:pfam17874  37 LARGLATFVLGEAYLCLGDLDAALQAMREAEALARR---ADSPHVTLWaLLQQGEILRAQGRLHQALETYQQALQLARDH 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   274 LGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvLGKFHPDVAKQ-LSNLALLCQNQGKAEEVEYYYRRALE 352
Cdd:pfam17874 114 GLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQL----GRQWEPDAAVDaYVLLARIALAQGELEEALTLLRRAEL 189


                  ....
gi 13878553   353 IYAT 356
Cdd:pfam17874 190 LARQ 193
TPR_12 pfam13424
Tetratricopeptide repeat;
365-481 1.58e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.45  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   365 VAKTKNNLASCYLKQGKYQDAETLYKEILTRAhEKEFGSvngdnkpiwmhaeereeskdkrrdsapygeygswykackvD 444
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIA-RRLLGP----------------------------------------D 40

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 13878553   445 SPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQ 481
Cdd:pfam13424  41 HPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_10 pfam13374
Tetratricopeptide repeat;
323-364 1.96e-04

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 39.02  E-value: 1.96e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 13878553   323 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPN 364
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 282-314 2.13e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 2.13e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 13878553    282 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 246-311 2.23e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.63  E-value: 2.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553   246 LALVYRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 311
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR_7 pfam13176
Tetratricopeptide repeat;
284-318 3.64e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.29  E-value: 3.64e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 13878553   284 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 318
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 250-374 4.46e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 4.46e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 250 YRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKvlgkfHPDVAKQLSN 329
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPD-----SPKAPDALLK 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 13878553 330 LALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAKTKNNLAS 374
Cdd:COG1729  73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLAR 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 320-398 6.05e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 6.05e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13878553 320 HPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:COG4235  13 NPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRL--------DPDNADALLDLAEALLAAGDTEEAEELLERALALDPD 83
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 26-132 1.07e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553    26 QGLETLRGEHRALLAPLVAPEAGEAEpgSQERCILLRRSLEAIELGLGEAQVILA-LSSHLGAVESEKQKLRAQVRRLVQ 104
Cdd:pfam19220  62 AAYGKLRRELAGLTRRLSAAEGELEE--LVARLAKLEAALREAEAAKEELRIELRdKTAQAEALERQLAAETEQNRALEE 139

                          90       100
                  ....*....|....*....|....*...
gi 13878553   105 ENQWLREELAGTQQKLQRSEQAVAQLEE 132
Cdd:pfam19220 140 ENKALREEAQAAEKALQRAEGELATARE 167
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
195-274 1.18e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 1.18e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553 195 PARLRTLHNLVIQYASQGRYEVAVPLcKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
Cdd:COG3063  23 PDNADALNNLGLLLLEQGRYDEAIAL-EKALK--------LDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 222-396 1.33e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   222 KQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEA 301
Cdd:TIGR02917 618 NKAVSSFKKLLALQ-PDSALALLLLADAYAVMKNYAKAITSLKRALEL--------KPDNTEAQIGLAQLLLAAKRTESA 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   302 EPLCKRALEIREKvlgkfHPDVAKQLSNLALLcqnQGKAEEVEYYYRRALEIYAT-----RLG----------------- 359
Cdd:TIGR02917 689 KKIAKSLQKQHPK-----AALGFELEGDLYLR---QKDYPAAIQAYRKALKRAPSsqnaiKLHrallasgntaeavktle 760

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 13878553   360 ---PDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 396
Cdd:TIGR02917 761 awlKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKA 800
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 207-400 1.79e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 40.76  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   207 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLN 286
Cdd:pfam17874  89 ILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQ-----LGRQWEPDAAVDA 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   287 NLAVLYGK--RGKYKEAEPLCKRALEIREKvlGKFHPD----VAKQLSNLALLCQNQGKAeeveyyyRRALEIYATRLGP 360
Cdd:pfam17874 164 YVLLARIAlaQGELEEALTLLRRAELLARQ--SFFHVDwlanAERVRVRLWLARGDLRAA-------VRWLRAAEPPSDA 234

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 13878553   361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 400
Cdd:pfam17874 235 DNHFLERELRNLARVLLALGRFDDALSLLERLQNLAEQLG 274
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 237-356 2.31e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.12  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553   237 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvl 316
Cdd:TIGR00990 464 PEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPM-YMNVLPLINKALALFQWKQDFIEAENLCEKALII----- 537

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 13878553   317 gkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
Cdd:TIGR00990 538 ---DPECDIAVATMAQLLLQQGDVDEALKLFERAAELART 574
TPR_10 pfam13374
Tetratricopeptide repeat;
365-402 2.71e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.94  E-value: 2.71e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 13878553   365 VAKTKNNLASCYLKQGKYQDAETLYKEILTRaHEKEFG 402
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAI-RERVLG 37
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 291-471 2.98e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.67  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  291 LYgKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEV---------------------EY---- 345
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13878553  346 ------------YYRRALEI-------YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNG 406
Cdd:NF040586 481 agglgadlralgRFREALELdeetlerHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-----RRRVLG 555

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13878553  407 DNKP----IWMH-------AEEREESKDKRRDSAPYGEygswYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 471
Cdd:NF040586 556 PDHPrtllSANNlardlreLGRYAEALDLLEEALERYR----EVLGGPDHPDTLRAAKSLAVALRRAGRLEEALEL 627
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 366-398 3.62e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 3.62e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 13878553    366 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
366-398 4.86e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.86e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 13878553   366 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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