|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
255-489 |
3.31e-73 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 231.72 E-value: 3.31e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 255 EQWRALTRQDQQRRELITNISHDLRTPLTSLHGYLETLsLKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESG 334
Cdd:COG2205 4 EALEELEELERLKSEFLANVSHELRTPLTSILGAAELL-LDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 335 SVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRD 414
Cdd:COG2205 83 KLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREG 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 976581553 415 DRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALA 489
Cdd:COG2205 163 DGVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLA 237
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
155-489 |
6.26e-63 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 209.79 E-value: 6.26e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 155 YVVLLGEAHDRLAARVDAGNVLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPDTQPPVPRPAPGR 234
Cdd:COG5002 53 ALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLG 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 235 RGDDLAVLESAFAQMADRIGEQWRALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSLKADTLADaERRRYLSVALAQ 314
Cdd:COG5002 133 RLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADDPE-ERREYLEIILEE 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 315 STKVGRLAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLD 394
Cdd:COG5002 212 AERLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLD 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 395 NALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQR------PVSGGTstngGLGLLIVHRMLALNGS 468
Cdd:COG5002 292 NAIKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRvdksrsRETGGT----GLGLAIVKHIVEAHGG 367
|
330 340
....*....|....*....|.
gi 976581553 469 DIRLVDRDGRGAVFEFALALA 489
Cdd:COG5002 368 RIWVESEPGKGTTFTITLPLA 388
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
158-489 |
1.66e-62 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 207.07 E-value: 1.66e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 158 LLGEAHDRLAARVDAGNVLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPDTQPPVPRPAPGRRGD 237
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 238 DLAVLESAFAQMADRIGEQWRALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSLKADtladAERRRYLSVALAQSTK 317
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELD----EEQREYLETILRSADR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 318 VGRLAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNAL 397
Cdd:COG0642 157 LLRLINDLLDLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 398 RHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDG 477
Cdd:COG0642 237 KYTPEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPG 316
|
330
....*....|..
gi 976581553 478 RGAVFEFALALA 489
Cdd:COG0642 317 KGTTFTVTLPLA 328
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
177-489 |
7.74e-42 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 155.39 E-value: 7.74e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 177 RTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPdtqppvprPAPGRRGDDLAVLESAFAQMADRI-GE 255
Cdd:PRK11100 182 RRILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEGKPV--------PLPKLGSSELRELAQALESMRVKLeGK 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 256 QW-----RALTrqdqqrrelitnisHDLRTPLTSLHGYLETLslkADTLADAERRRYLSVALAQSTKVGRLAQALFELAR 330
Cdd:PRK11100 254 AYveqyvQTLT--------------HELKSPLAAIRGAAELL---QEDPPPEDRARFTGNILTQSARLQQLIDRLLELAR 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 331 LESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPrvPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVAL 410
Cdd:PRK11100 317 LEQRQELEVLEPVALAALLEELVEAREAQAAAKGITLRLRPDD--ARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSA 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 411 TPRDDRVVVTVSDTGAGIPLARRAGLFQR---PQRPVSGGTSTngGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALA 487
Cdd:PRK11100 395 EVDGEQVALSVEDQGPGIPDYALPRIFERfysLPRPANGRKST--GLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
..
gi 976581553 488 LA 489
Cdd:PRK11100 473 RH 474
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
184-493 |
4.43e-39 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 147.03 E-value: 4.43e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 184 AVVALLGLVAGLIAFSF---ITRPLRRLTDAMRRFdANGAPDTQPPVprpapgRRGDDLAVLESAFAQMADRIGEQWRAL 260
Cdd:COG5000 13 LIALLLLLLALWLALLLarrLTRPLRRLAEATRAV-AAGDLSVRLPV------TGDDEIGELARAFNRMTDQLKEQREEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 261 TRQ----------------------------------------------------------------------------- 263
Cdd:COG5000 86 EERrryletilenlpagvivldadgritlanpaaerllgipleeligkpleellpeldlaellrealergwqeeieltrd 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 264 ----------------------------DQQR----RELITNISHDLRTPLTSLHGYLETLS---LKADTLADAERRRYL 308
Cdd:COG5000 166 grrtllvrasplrddgyvivfdditellRAERlaawGELARRIAHEIKNPLTPIQLSAERLRrklADKLEEDREDLERAL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 309 SVALAQSTKVGRLAQALFELARLEsgsvQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERV 388
Cdd:COG5000 246 DTIIRQVDRLKRIVDEFLDFARLP----EPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 389 LTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQrpqrP-VSggTSTNG-GLGLLIVHRMLALN 466
Cdd:COG5000 322 LINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFE----PfFT--TKPKGtGLGLAIVKKIVEEH 395
|
410 420
....*....|....*....|....*..
gi 976581553 467 GSDIRLVDRDGRGAVFEFALALAIAQP 493
Cdd:COG5000 396 GGTIELESRPGGGTTFTIRLPLAEEAE 422
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
2-478 |
4.30e-35 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 136.36 E-value: 4.30e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 2 KLNLTQRLSCVFAVLLLACSGASAWLQIRAND----MREKEVVQALSRDLAAHIASSTPLMDanglRPDAVRRLFGQLMG 77
Cdd:TIGR01386 1 PRSLTLRLALLFAAVTALVFALSGFMLYSSLErhfeERDREELQGKLEQVRRFLRDPADLDE----DIKRLQEKIDDLLV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 78 VNPSVEVYLLDNAGRIEGDDAPPGHVKRSRVDLAPVQRfiagEPLPILGDDPRSVDARKVfsAAPLQRAGQPPSGYVyVV 157
Cdd:TIGR01386 77 GHSDLALSILNPDGRLLFERAQGAALVPAVAANDALLE----LDQADAKMTHYRSILRSV--AALPGGKGRKPVQIT-VA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 158 LLGEAHDRLAARVdagnvLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPDTQPPVPRPApgrrgd 237
Cdd:TIGR01386 150 LDINAHTHLLDAL-----RKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRAPA------ 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 238 DLAVLESAFAQMADRIGEQWRALTRqdqqrreLITNISHDLRTPLTSLHGYLETLSLKADTLAdaERRRYLSVALAQSTK 317
Cdd:TIGR01386 219 ELRELAQSFNAMLGRLEDAFQRLSQ-------FSADLAHELRTPLTNLLGQTQVALSQPRTGE--EYREVLESNLEELER 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 318 VGRLAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAvsaDLAMIERVLTNLLDNAL 397
Cdd:TIGR01386 290 LSRMVSDMLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGLVRG---DPQMFRRAISNLLSNAL 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 398 RHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQR--PVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDR 475
Cdd:TIGR01386 367 RHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRvdPARSNSGEGTGLGLAIVRSIMEAHGGRASAESP 446
|
...
gi 976581553 476 DGR 478
Cdd:TIGR01386 447 DGK 449
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
155-489 |
2.30e-34 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 132.61 E-value: 2.30e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 155 YVVLLGEAHDRLAARVDAGNVLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPDTQPPVPRPAPGR 234
Cdd:COG4191 7 LLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 235 RGDDLAVLESAFAQMADRIGEQWRALTRQDQQRR-----------------------ELITNISHDLRTPLTSLHGYLET 291
Cdd:COG4191 87 LLLLEALLLLLLAALDAEENAELEELERDITELEraeeelrelqeqlvqseklaalgELAAGIAHEINNPLAAILGNAEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 292 LSLKADTLADAER-RRYLSVALAQSTKVGRLAQALFELARLESgsvqAEREPFSLVDLVQDVFQKFELAAQSRGIALQAR 370
Cdd:COG4191 167 LRRRLEDEPDPEElREALERILEGAERAAEIVRSLRAFSRRDE----EEREPVDLNELIDEALELLRPRLKARGIEVELD 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 371 IPPRVPAVSADLAMIERVLTNLLDNALR--HTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQrP---QRPVS 445
Cdd:COG4191 243 LPPDLPPVLGDPGQLEQVLLNLLINAIDamEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFE-PfftTKPVG 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 976581553 446 GGTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALA 489
Cdd:COG4191 322 KGT----GLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPLA 361
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
14-486 |
1.71e-31 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 127.21 E-value: 1.71e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 14 AVLLLACSGASAWLQIRANDMREKEVVQALSRDLAAHIASSTPLMDANGLRPDAVRRLFGQLMGVNPSVEVYLLDNAGRI 93
Cdd:COG4251 20 LLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 94 EGDDAPPGHVKRSRVDLAPVQRFIAGEPLPILGDDPRSVDARKVFSAAPLQRAGQPPSGYVYVVLLGEAHDRLAARVDAG 173
Cdd:COG4251 100 LLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 174 NVLRTTLWSMAVVALLGLVAGLIAFSFITRpLRRLTDAMRRFDANGAPDTQPPVPRPAPGRRGDDLAVLESAFAQMADRI 253
Cdd:COG4251 180 LLLLLLLVLLLLLLLLLLLLLLLLRLLLEL-LLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELR 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 254 GEQWRALTRQDQQRREL-ITN---------ISHDLRTPLTSLHGYLETLSLKADTLADAERRRYLSVALAQSTKVGRLAQ 323
Cdd:COG4251 259 LELEELEEELEERTAELeRSNeeleqfayvASHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALID 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 324 ALFELARLesGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALqaRIPPrVPAVSADLAMIERVLTNLLDNALRHTP-- 401
Cdd:COG4251 339 DLLAYSRV--GRQELEFEPVDLNELLEEVLEDLEPRIEERGAEI--EVGP-LPTVRGDPTLLRQVFQNLISNAIKYSRpg 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 402 QHGAIEVALTPRDDRVVVTVSDTGAGIPLARRA---GLFQR-PQRPVSGGTstngGLGLLIVHRMLALNGSDIRLVDRDG 477
Cdd:COG4251 414 EPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEkifEIFQRlHSRDEYEGT----GIGLAIVKKIVERHGGRIWVESEPG 489
|
....*....
gi 976581553 478 RGAVFEFAL 486
Cdd:COG4251 490 EGATFYFTL 498
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
253-486 |
8.60e-28 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 116.99 E-value: 8.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 253 IGEQWRALTRQDQQRR-----ELITNISHDLRTPLTSLHGYLETLSlkaDTLADAERRRYLSVALAQSTKVGRLAQALFE 327
Cdd:PRK11360 371 LTERKRLQRRVARQERlaalgELVAGVAHEIRNPLTAIRGYVQIWR---QQTSDPPSQEYLSVVLREVDRLNKVIDQLLE 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 328 LARlesgSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIE 407
Cdd:PRK11360 448 FSR----PRESQWQPVSLNALVEEVLQLFQTAGVQARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIR 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 408 VAL-TPRDDRVVVTVSDTGAGIPLARRAGLFQ-----RPQrpvsgGTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAV 481
Cdd:PRK11360 524 IRTwQYSDGQVAVSIEDNGCGIDPELLKKIFDpffttKAK-----GT----GLGLALSQRIINAHGGDIEVESEPGVGTT 594
|
....*
gi 976581553 482 FEFAL 486
Cdd:PRK11360 595 FTLYL 599
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
248-486 |
4.58e-27 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 112.35 E-value: 4.58e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 248 QMAD---RIGEQWRALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSL----KADTLADAERRRYLSVALAQSTKVGR 320
Cdd:PRK09303 129 QLSDelfVLRQENETLLEQLKFKDRVLAMLAHDLRTPLTAASLALETLELgqidEDTELKPALIEQLQDQARRQLEEIER 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 321 LAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHT 400
Cdd:PRK09303 209 LITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYT 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 401 PQHGAIEVALTPR-DDRVVVTVSDTGAGIPLARRAGLFQ---RPQRpvSGGTStnG-GLGLLIVHRMLALNGSDIRLVDR 475
Cdd:PRK09303 289 PEGGTITLSMLHRtTQKVQVSICDTGPGIPEEEQERIFEdrvRLPR--DEGTE--GyGIGLSVCRRIVRVHYGQIWVDSE 364
|
250
....*....|.
gi 976581553 476 DGRGAVFEFAL 486
Cdd:PRK09303 365 PGQGSCFHFTL 375
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
385-486 |
1.19e-26 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 103.45 E-value: 1.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLA 464
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREGGGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 976581553 465 LNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
30-467 |
1.85e-26 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 111.84 E-value: 1.85e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 30 RANDMREKEVVQALSRDLAAHiasstplMDANGLRPDAVRRLFGQLmgvnPSVEvylLDNAGRIEGDDAPPGHVKRSRVD 109
Cdd:NF012163 42 DGNEQRLQRLSDALGEQYAQH-------GNWRFLRNNGDRWVRQLL----RTLE---HDNDSDKPGPGLPDHLGWRSRLW 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 110 LAPVQ-RFIAGEPLPILGDDPRSvdarkvfsaaPLQRAGQPpSGYVYVVLLGEAHDRLAARVDagNVLRTTLWsmAVVAL 188
Cdd:NF012163 108 LVDANhRFVVGPPDPVSDDGTRR----------PILVNGQE-VGALGASPVERLTRNTDINFD--SQQKRASW--LIVAL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 189 LGLVAGLIAF---SFITRPLRRLTDAMRRFDANgapDTQPPVPRpapgRRGDDLAVLESAFAQMADrigeqwrALTRQDQ 265
Cdd:NF012163 173 ALLLAALAAFllaRGLLAPVKRLVEATHRLAAG---DYTTRVTP----TSNDELGKLAQDFNQLAS-------TLEKNEQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 266 QRRELITNISHDLRTPLTSLHGYLETLSlkaDTLADAERRRYLSVaLAQSTKVGRLAQALFELARLESGSVQAEREPFSL 345
Cdd:NF012163 239 MRRDFMADISHELRTPLAVLRAELEAIQ---DGIRKFTPESLDSL-QAEVGTLTKLVDDLHDLSMSDEGALAYQKASVDL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 346 VDLVQDVFQKFELAAQSRGIALQARIPPRvPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTG 425
Cdd:NF012163 315 VPLLEVEGGAFRERFASAGLELEVSLPDS-SLVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISASQRPKEVTLTVADSA 393
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 976581553 426 AGIPLARRAGLFQR------PQRPVSGGTstngGLGLLIVHRM-LALNG 467
Cdd:NF012163 394 PGVSDEQLARLFERfyrvevSRNRASGGS----GLGLAISLNIvQAHGG 438
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
255-488 |
3.03e-25 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 109.74 E-value: 3.03e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 255 EQWRALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSLKadtLAdAERRRYLSVALA---QSTKVGRLAQALFELARL 331
Cdd:PRK10490 652 EQARLASEREQLRNALLAALSHDLRTPLTVLFGQAEILTLD---LA-SEGSPHARQASEirqQVLNTTRLVNNLLDMARI 727
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 332 ESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQarIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALT 411
Cdd:PRK10490 728 QSGGFNLRKEWLTLEEVVGSALQMLEPGLSGHPINLS--LPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAH 805
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 976581553 412 PRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALAL 488
Cdd:PRK10490 806 VEGERLQLDVWDNGPGIPPGQEQLIFDKFARGNKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPL 882
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
258-495 |
1.31e-24 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 104.93 E-value: 1.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 258 RALTRQDQQR--RELITNISHDLRTPLTSLHGYLETLSLKadtLADAERRRYLSVALAQSTKVGRLAQALFELARLEsgs 335
Cdd:COG3852 124 RELRRAEKLAavGELAAGLAHEIRNPLTGIRGAAQLLERE---LPDDELREYTQLIIEEADRLNNLVDRLLSFSRPR--- 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 336 vQAEREPFSLVDLVQDVFQKFELAAQsRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEV------- 408
Cdd:COG3852 198 -PPEREPVNLHEVLERVLELLRAEAP-KNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIrtrverq 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 409 ---ALTPRDDRVVVTVSDTGAGIPLARRAGLFQrpqrP-VSG---GTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAV 481
Cdd:COG3852 276 vtlGGLRPRLYVRIEVIDNGPGIPEEILDRIFE----PfFTTkekGT----GLGLAIVQKIVEQHGGTIEVESEPGKGTT 347
|
250
....*....|....
gi 976581553 482 FEFALALAIAQPAP 495
Cdd:COG3852 348 FRIYLPLEQAEEEP 361
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
380-486 |
1.39e-24 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 98.10 E-value: 1.39e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 380 ADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG-GLGLLI 458
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGtGLGLSI 80
|
90 100
....*....|....*....|....*...
gi 976581553 459 VHRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
186-495 |
1.12e-23 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 105.11 E-value: 1.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 186 VALLGLVAGLIAFSFI-----TRPLRRLTDAMrrfdangAPDTQPPVPRPAPGRRGDDLAVLESAFAQMADRIGEQW--- 257
Cdd:PRK15347 301 FALLILVLLTSVLFLLlrrylAKPLWRFVDII-------NKTGPAALEPRLPENRLDELGSIAKAYNQLLDTLNEQYdtl 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 258 --------RALTRQDQQ-----RR--ELITNISHDLRTPltsLHGYLETLSLKADTLADAERRRYLSVALAQSTKVGRLA 322
Cdd:PRK15347 374 enkvaertQALAEAKQRaeqanKRksEHLTTISHEIRTP---LNGVLGALELLQNTPLTAEQMDLADTARQCTLSLLAII 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 323 QALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAM-IERVLTNLLDNALRHTP 401
Cdd:PRK15347 451 NNLLDFSRIESGQMTLSLEETALLPLLDQAMLTIQGPAQSKSLTLRTFVGAHVPLYLHLDSLrLRQILVNLLGNAVKFTE 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 402 qHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQrpqrPV--SGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRG 479
Cdd:PRK15347 531 -TGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFT----PFyqADTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVG 605
|
330
....*....|....*..
gi 976581553 480 AVFEFALAL-AIAQPAP 495
Cdd:PRK15347 606 SCFSLVLPLnEYAPPEP 622
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
270-495 |
6.45e-23 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 101.40 E-value: 6.45e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 270 LITNISHDLRTPLTSLHGYLETLSLKADtlADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQaerePFSLVDLV 349
Cdd:PRK10364 240 LAAGVAHEIRNPLSSIKGLAKYFAERAP--AGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQ----AVDLNDLI 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 350 QDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIP 429
Cdd:PRK10364 314 NHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIA 393
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 976581553 430 LARRAGLFQRPQRPVSGGTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIAQPAP 495
Cdd:PRK10364 394 ADQLEAIFTPYFTTKAEGT----GLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVNITRRDP 455
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
183-498 |
7.03e-23 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 100.83 E-value: 7.03e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 183 MAVVALLGLVAGLIAFSFItRP----LRRLTDAMRRFdANGAPDTQPPVPrpaPGRRGDDLAVlesAFAQMADRIGeqwr 258
Cdd:PRK10604 139 IALLALIGLSLAFPVFLWM-RPhwqdMLKLEAAAQRL-GDGHLAERIHFD---EGSSLERLGV---AFNQMADNIN---- 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 259 ALTrqdQQRRELITNISHDLRTPLTSLHGYLETLslkaDTLADAERrrylsvaLAQSTKVGRLaQALFE----LARLESG 334
Cdd:PRK10604 207 ALI---ASKKQLIDGIAHELRTPLVRLRYRLEMS----DNLSAAES-------QALNRDIGQL-EALIEelltYARLDRP 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 335 SVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQarIPPRVPAVSADLAMIERVLTNLLDNALRHTpqHGAIEVALTPRD 414
Cdd:PRK10604 272 QNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLD--TPHQGDYGALDMRLMERVLDNLLNNALRYA--HSRVRVSLLLDG 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 415 DRVVVTVSDTGAGIPLARRAGLFQRPQR-PVSGGTSTNG-GLGLLIVHR-MLALNGSdIRLVDRDGRGAVFEFALALAIA 491
Cdd:PRK10604 348 NQACLIVEDDGPGIPPEERERVFEPFVRlDPSRDRATGGcGLGLAIVHSiALAMGGS-VNCDESELGGARFSFSWPVWHN 426
|
....*..
gi 976581553 492 QPAPGDP 498
Cdd:PRK10604 427 LPQFTSA 433
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
140-486 |
1.01e-22 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 101.00 E-value: 1.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 140 AAPLQRAGQPPSGYVYVVLLGeahdrLAARVDAGNVLRTTLWSMAVV-ALLGLVAGLIAFSFITRPLRRLTDAM-----R 213
Cdd:PRK09835 152 ALPVGPLVDGKPIYTLLIALS-----IDFHLHYINDLKNKLIMTASViSLLIVFIVLLAVHKGHAPIRSVSRQIqnitsK 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 214 RFDANGAPDTQPPvprpapgrrgdDLAVLESAFAQMADRIGEqwrALTRQDQqrreLITNISHDLRTPLTSLHGYLETLS 293
Cdd:PRK09835 227 DLDVRLDPQTVPI-----------ELEQLVLSFNHMIERIED---VFTRQSN----FSADIAHEIRTPITNLITQTEIAL 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 294 LKADTLADAERRRYLSvaLAQSTKVGRLAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALqaRIPP 373
Cdd:PRK09835 289 SQSRSQKELEDVLYSN--LEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDFFEAWAEERGVEL--RFVG 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 374 RVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQR-----PQRPVSGGT 448
Cdd:PRK09835 365 DPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRfyrvdPSRQRKGEG 444
|
330 340 350
....*....|....*....|....*....|....*...
gi 976581553 449 StngGLGLLIVHRMLALNGSDIRlVDRDGRGAVFEFAL 486
Cdd:PRK09835 445 S---GIGLAIVKSIVVAHKGTVA-VTSDARGTRFVISL 478
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
267-492 |
2.89e-22 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 100.96 E-value: 2.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 267 RRELITNISHDLRTPLTSLHGYLETLSlkADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQAEREPFSLV 346
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLS--GSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIP 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 347 DLVQDVFQKFELAAQSRGIALQ-ARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQhGAIEV--ALTPRDDR---VVVT 420
Cdd:PRK09959 790 TLVQNTCHSFGAIAASKSIALScSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTTE-GAVKIttSLGHIDDNhavIKMT 868
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 976581553 421 VSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIAQ 492
Cdd:PRK09959 869 IMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEISQ 940
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
178-471 |
3.00e-22 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 99.32 E-value: 3.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 178 TTLwsMAVVALLGLVAGLIAfsfitrPLRRLTDAMRRFdANGAPDTqppvpRPAPGRRgDDLAVLESAFAQMAdrigeqw 257
Cdd:PRK10549 173 STL--LAALATFLLARGLLA------PVKRLVEGTHKL-AAGDFTT-----RVTPTSR-DELGRLAQDFNQLA------- 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 258 RALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSlkadtlaDAERR---RYLSVALAQSTKVGRLAQALFELARLESG 334
Cdd:PRK10549 231 STLEKNEQMRRDFMADISHELRTPLAVLRGELEAIQ-------DGVRKftpESVASLQAEVGTLTKLVDDLHQLSLSDEG 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 335 SVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPaVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRD 414
Cdd:PRK10549 304 ALAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSAT-VFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRD 382
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 976581553 415 DRVVVTVSDTGAGIPLARRAGLFQRPQRP------VSGGTstngGLGLLIVHRMLALNGSDIR 471
Cdd:PRK10549 383 KTLRLTFADSAPGVSDEQLQKLFERFYRTegsrnrASGGS----GLGLAICLNIVEAHNGRII 441
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
181-479 |
4.05e-22 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 98.95 E-value: 4.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 181 WSMAVVALLGLVAGLIAFSFitRPLRRLTDAMRRfdanGAPDTQPPVPRpapGRRGDDLAVLESAFAQMADRIGEQwraL 260
Cdd:PRK10337 167 WLVALPIMLIILMVLLGREL--APLKKLALALRM----RDPDSETPLNA---TGVPSEVRPLVEALNQLFARTHAM---M 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 261 TRQdqqrRELITNISHDLRTPLTSLHGYLETLSLKADtlaDAERRRYlsvALAQSTK----VGRLAQALFELARLESGSV 336
Cdd:PRK10337 235 VRE----RRFTSDAAHELRSPLAALKVQTEVAQLSDD---DPQARKK---ALLQLHAgidrATRLVDQLLTLSRLDSLDN 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 337 QAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDdr 416
Cdd:PRK10337 305 LQDVAEIPLEDLLQSAVMDIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN-- 382
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 976581553 417 vvVTVSDTGAGIP---LARRAGLFQRPqrpvSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRG 479
Cdd:PRK10337 383 --FTVRDNGPGVTpeaLARIGERFYRP----PGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGG 442
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
380-490 |
4.08e-22 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 91.28 E-value: 4.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 380 ADLAMIERVLTNLLDNALRHTPQHGAIEVALTpRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTStNGGLGLLIV 459
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGG-GTGLGLSIV 78
|
90 100 110
....*....|....*....|....*....|.
gi 976581553 460 HRMLALNGSDIRLVDRDGRGAVFEFALALAI 490
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
256-483 |
7.00e-20 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 91.45 E-value: 7.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 256 QWRALTRQDQQRRELITNI---SHDLRTPLTSLHGYLETLslkadtlADAERRRYLsvalaqsTKVGRLAQAL--FELAR 330
Cdd:COG3290 175 ELERLEEELEGVKELAEALraqRHDFRNHLHTISGLLQLG-------EYDEALEYI-------DEISEELQELidSLLSR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 331 LESGSVQAerepfslvdLVQDvfqKFELAAQsRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHT----PQHGAI 406
Cdd:COG3290 241 IGNPVLAA---------LLLG---KAARARE-RGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDNAIEAVeklpEEERRV 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 407 EVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRpqrpvsgGTST----NGGLGLLIVHRMLALNGSDIRLVDRDGRGAVF 482
Cdd:COG3290 308 ELSIRDDGDELVIEVEDSGPGIPEELLEKIFER-------GFSTklgeGRGLGLALVKQIVEKYGGTIEVESEEGEGTVF 380
|
.
gi 976581553 483 E 483
Cdd:COG3290 381 T 381
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
269-486 |
1.10e-19 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 91.57 E-value: 1.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 269 ELITNISHDLRTPLTSLHGYLETLSLKADTladaERRRYLSVALAqstkvgrlaqalfELARLES--------GSVQAER 340
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQLLKDTIDE----EQKTYLDIMLS-------------ELDRIESiiseflvlAKPQAIK 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 341 -EPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTP-RDDRVV 418
Cdd:COG5809 335 yEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAeDDDKVV 414
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 976581553 419 VTVSDTGAGIPLARRAGLFQrpqrPV----SGGTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:COG5809 415 ISVTDEGCGIPEERLKKLGE----PFyttkEKGT----GLGLMVSYKIIEEHGGKITVESEVGKGTTFSITL 478
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
188-495 |
1.27e-17 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 86.11 E-value: 1.27e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 188 LLGLvAGLIAFSFI---------TRPLRRLTDAMRRFdANGapDTQPPVPRPAPGRRGDDLAVLESAF-----------A 247
Cdd:PRK11466 335 LLGM-VSLCALILIlwrvvyrsvTRPLAEQTQALQRL-LDG--DIDSPFPETAGVRELDTIGRLMDAFrsnvhalnrhrE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 248 QMADRIGEQWRALT------RQ--------DQQRRELITNISHDLRTPLtslHGYLETLSLKADTLADAERRRYLSVALA 313
Cdd:PRK11466 411 QLAAQVKARTAELQelviehRQaraeaekaSQAKSAFLAAMSHEIRTPL---YGILGTAQLLADNPALNAQRDDLRAITD 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 314 QSTKVGRLAQALFELARLESG--SVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPA-VSADLAMIERVLT 390
Cdd:PRK11466 488 SGESLLTILNDILDYSAIEAGgkNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATDIADDLPTaLMGDPRRIRQVIT 567
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 391 NLLDNALRHTpQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQrPQRPVS---GGTstngGLGLLIVHRMLALNG 467
Cdd:PRK11466 568 NLLSNALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQ-PFVQVSgkrGGT----GLGLTISSRLAQAMG 641
|
330 340
....*....|....*....|....*...
gi 976581553 468 SDIRLVDRDGRGAVFEFALALAIAQPAP 495
Cdd:PRK11466 642 GELSATSTPEVGSCFCLRLPLRVATAPV 669
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
247-498 |
1.30e-17 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 86.06 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 247 AQMADRIgeqwraltrqdqqRRELITNISHDLRTPL------------TSLHG----YLETLSLKADTLadaerrryLSV 310
Cdd:PRK11107 286 AQEAARI-------------KSEFLANMSHELRTPLngvigftrqtlkTPLTPtqrdYLQTIERSANNL--------LAI 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 311 ---ALAQStkvgrlaqalfelaRLESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVP-AVSADLAMIE 386
Cdd:PRK11107 345 indILDFS--------------KLEAGKLVLENIPFSLRETLDEVVTLLAHSAHEKGLELTLNIDPDVPdNVIGDPLRLQ 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 387 RVLTNLLDNALRHTPQhGAIEVALTPR---DDRVV--VTVSDTGAGIPLARRAGLFQ--RpQRPVS-----GGTstngGL 454
Cdd:PRK11107 411 QIITNLVGNAIKFTES-GNIDILVELRalsNTKVQleVQIRDTGIGISERQQSQLFQafR-QADASisrrhGGT----GL 484
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 976581553 455 GLLI----VHRMlalnGSDIRLVDRDGRGAVFEFALALAIAQPAPGDP 498
Cdd:PRK11107 485 GLVItqklVNEM----GGDISFHSQPNRGSTFWFHLPLDLNPNPIIDG 528
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
185-479 |
1.50e-17 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 83.86 E-value: 1.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 185 VVALLGLVAGLIAFSFITRPLRRLTDAMrrfdANGAPDTQPPVPrpapgrrgDDLAVLE-----SAFAQMADRigeqwra 259
Cdd:PRK10755 69 VMVSLTLLICFQAVRWITRPLAELQKEL----EARTADNLTPIA--------IHSSTLEieavtSALNQLVSR------- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 260 LTRQDQQRRELITNISHDLRTPLTSLHGYLETLS----LKADTLadAERRRYLSVALAQSTKVGRLAQAlfelarLESGS 335
Cdd:PRK10755 130 LTSTLDQERLFTADVAHELRTPLAGIRLHLELLEkqhhIDVAPL--IARLDQMMHTVEQLLQLARAGQS------FSSGH 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 336 VQAerepfslVDLVQDVF----QKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALT 411
Cdd:PRK10755 202 YQT-------VKLLEDVIlpsqDELSEMLEQRQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLS 274
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 976581553 412 PRDDRVVVTVSDTGAGIPLARRAGL---FQR-PQRpvSGGTstngGLGLLIVHRMLALNGSDIRLVDRDGRG 479
Cdd:PRK10755 275 QEDGGAVLAVEDEGPGIDESKCGELskaFVRmDSR--YGGI----GLGLSIVSRITQLHHGQFFLQNRQERS 340
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
161-484 |
4.50e-17 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 83.97 E-value: 4.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 161 EAHDRLAARVDAGNVLrttLWSMAVVALLglVAGLIAFSFITRPL-RRLT---DAMRRFdANGAPDTQPPVPrpapgrrG 236
Cdd:COG4192 312 ALNQETAQLVQQSGIL---LLAIALLSLL--LAVLINYFYVRRRLvKRLNalsDAMAAI-AAGDLDVPIPVD-------G 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 237 DD------------LAVLESAFAQMADRIGEQWRALTRQDQQRRELI------------TNISHDLRTPLTSLHGYLETL 292
Cdd:COG4192 379 NDeigriarllrvfRDQAIEKTQELETEIEERKRIEKNLRQTQDELIqaakmavvgqtmTSLAHELNQPLNAMSMYLFSA 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 293 SLKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQaerePFSLVDLVQDVFQKFELAAQSRGIALQarIP 372
Cdd:COG4192 459 KKALEQENYAQLPTSLDKIEGLIERMDKIIKSLRQFSRKSDTPLQ----PVDLRQVIEQAWELVESRAKPQQITLH--IP 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 373 PRVPaVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRagLFQrpqrPVSGGTSTNG 452
Cdd:COG4192 533 DDLM-VQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLVDK--LFT----PFTTTKEVGL 605
|
330 340 350
....*....|....*....|....*....|....
gi 976581553 453 GLGLLIVHRMLALNGSDIRLVDRDGRGA--VFEF 484
Cdd:COG4192 606 GLGLSICRSIMQQFGGDLYLASTLERGAmvILEF 639
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
171-486 |
3.33e-16 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 80.83 E-value: 3.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 171 DAGNVLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPdtqppvprPAPGRRGDDLAVLESAFAQMA 250
Cdd:COG2972 151 GLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--------RLEVSGNDEIGILARSFNEMV 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 251 DRIGEQWRALTRQDQQRR--ELITNIS----HDLrtpltslhgY--LETLSlkadtladaerrrylsvALAQSTKVGRLA 322
Cdd:COG2972 223 ERIKELIEEVYELELEKKeaELKALQAqinpHFL---------FntLNSIR-----------------WLAELEDPEEAE 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 323 QALFELARLESGSVQAEREPFSL---VDLVQDVF--QKFELaaQSRgiaLQARIppRVPAVSADLAMIERVLTNLLDNAL 397
Cdd:COG2972 277 EMLEALSKLLRYSLSKGDELVTLeeeLELIKSYLeiQKLRF--GDR---LEVEI--EIDEELLDLLIPKLILQPLVENAI 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 398 RH----TPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGgtstnGGLGLLIVHRMLAL---NGSDI 470
Cdd:COG2972 350 EHgiepKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKGEG-----RGIGLRNVRERLKLyygEEYGL 424
|
330
....*....|....*.
gi 976581553 471 RLVDRDGRGAVFEFAL 486
Cdd:COG2972 425 EIESEPGEGTTVTIRI 440
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
265-459 |
1.00e-15 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 79.21 E-value: 1.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 265 QQRreLITNISHDLRTPLTSLHgyletlslkadtLADAERRRYL--SVALAQ-STKVGRLAQA---LFELARLESGSvQA 338
Cdd:PRK09470 243 QQR--LLSDISHELRTPLTRLQ------------LATALLRRRQgeSKELERiETEAQRLDSMindLLVLSRNQQKN-HL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 339 EREPFSLVDLVQDVFQ--KFElaAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHgaIEVALTPRDDR 416
Cdd:PRK09470 308 ERETFKANSLWSEVLEdaKFE--AEQMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHTK--IEVAFSVDKDG 383
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 976581553 417 VVVTVSDTGAGIPLARRAGLFqRPQRPV-------SGGTstngGLGLLIV 459
Cdd:PRK09470 384 LTITVDDDGPGVPEEEREQIF-RPFYRVdeardreSGGT----GLGLAIV 428
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
267-487 |
1.11e-15 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 78.90 E-value: 1.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 267 RRELITNISHDLRTPLTSLHGYLETlsLKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQAEREpfsLV 346
Cdd:PRK11006 204 RRNFFANVSHELRTPLTVLQGYLEM--MQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNE---KV 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 347 D--LVQDVFQKFELAAQSRGIALQARIPPRVpAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDT 424
Cdd:PRK11006 279 DvpMMLRVLEREAQTLSQGKHTITFEVDNSL-KVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDN 357
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 976581553 425 GAGIP---LARRAGLFQRPQRPVS---GGTstngGLGLLIV-HrmlALNGSDIRL--VDRDGRGAVFEFALA 487
Cdd:PRK11006 358 GPGIApehIPRLTERFYRVDKARSrqtGGS----GLGLAIVkH---ALSHHDSRLeiESEVGKGTRFSFVLP 422
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
381-486 |
2.30e-15 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 72.14 E-value: 2.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 381 DLAMIERVLTNLLDNALRHTPQHGAIEVALTP-RDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG--GLGLL 457
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKfRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGgtGLGLS 80
|
90 100
....*....|....*....|....*....
gi 976581553 458 IVHRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVEL 109
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
389-479 |
2.72e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 72.05 E-value: 2.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 389 LTNLLDNALRHTPQHGAIEVALTPRDDRVVVtVSDTGAGIPLARRAGLFQRPQRPvsGGTSTNG-GLGLLIVHRMLALNG 467
Cdd:cd16940 18 LRNLVDNAVRYSPQGSRVEIKLSADDGAVIR-VEDNGPGIDEEELEALFERFYRS--DGQNYGGsGLGLSIVKRIVELHG 94
|
90
....*....|..
gi 976581553 468 SDIRLVDRDGRG 479
Cdd:cd16940 95 GQIFLGNAQGGG 106
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
179-461 |
2.77e-15 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 77.64 E-value: 2.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 179 TLWSMAVVALLglVAGliAFSFI---TRPLRRLTDAMRRFdanGAPDTQPPVPRpapgrRG-DDLAVLESAFAQMADRIG 254
Cdd:PRK09467 156 FRYTLAIGLLS--VAG--GWLFIriqNRPLVALEHAALQV---GKGEIPPPLRE-----YGaSEVRSVTRAFNQMAAGIK 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 255 --EQWRALtrqdqqrreLITNISHDLRTPLTSLHGYLETLSLKADTLA-----DAERrrylsvalaqstkvgrlAQALFE 327
Cdd:PRK09467 224 qlEDDRTL---------LMAGVSHDLRTPLTRIRLATEMMSEEDGYLAesinkDIEE-----------------CNAIIE 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 328 --LARLESGSvQAEREPFSLVDLVQDVfqkfeLAAQS---RGIALQ-ARIPPRVPAVSadLAmIERVLTNLLDNALRHTp 401
Cdd:PRK09467 278 qfIDYLRTGQ-EMPMEMADLNALLGEV-----IAAESgyeREIETAlQPGPIEVPMNP--IA-IKRALANLVVNAARYG- 347
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 402 qHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHR 461
Cdd:PRK09467 348 -NGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARGSSGTGLGLAIVKR 406
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-488 |
1.04e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 69.77 E-value: 1.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALRHTpqHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG--GLGLLIVHRM 462
Cdd:cd16939 1 MARALDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGgfGLGLAIVHRV 78
|
90 100
....*....|....*....|....*.
gi 976581553 463 LALNGSDIRLVDRDGRGAVFEFALAL 488
Cdd:cd16939 79 ALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
388-486 |
1.59e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 69.44 E-value: 1.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 388 VLTNLLDNALRHTPqHGAIEVALTPRDD-----RVVVTVSDTGAGIPLARRAGLFQR-PQRPVS-----GGTstngGLGL 456
Cdd:cd16922 4 ILLNLLGNAIKFTE-EGEVTLRVSLEEEeedgvQLRFSVEDTGIGIPEEQQARLFEPfSQADSSttrkyGGT----GLGL 78
|
90 100 110
....*....|....*....|....*....|
gi 976581553 457 LIVHRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16922 79 AISKKLVELMGGDISVESEPGQGSTFTFTL 108
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
265-436 |
6.12e-13 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 71.50 E-value: 6.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 265 QQRRELITNISHDLRTPLTSLHGYLETLSlkaDTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQAEREPFS 344
Cdd:PRK10618 448 QARKAFLQNIGDELKQPLQSLAQLAAQLR---QTSDEEQQQPELDQLAEQSDVLVRLVDNIQLLNMLETQDWKPEQELFS 524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 345 LVDLVQDVFQKFELAAQSRGIAL--QARIPPRvPAVSADLAMIERVLTNLLDNALRHTpQHGAIEVALTP---RDDRVVV 419
Cdd:PRK10618 525 LQDLIDEVLPEVLPAIKRKGLQLliHNHLKAE-QLRIGDRDALRKILLLLLNYAITTT-AYGKITLEVDQdesSPDRLTI 602
|
170
....*....|....*..
gi 976581553 420 TVSDTGAGIPLARRAGL 436
Cdd:PRK10618 603 RILDTGAGVSIKELDNL 619
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
269-483 |
6.65e-13 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 70.53 E-value: 6.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 269 ELITNISHDLRTPLTSLHGYLETLSLKADtladaERRRYLSVALaqsTKVGRLAQALFELARLeSGSVQAEREPFSLVDL 348
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQLLQPGIE-----DKEEYFDIML---SELDRIESIISEFLAL-AKPQAVNKEKENINEL 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 349 VQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGI 428
Cdd:COG5805 360 IQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGI 439
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 976581553 429 PLARRAGLFQrpqrPVSgGTSTNG-GLGLLIVHRMLALNGSDIRLVDRDGRGAVFE 483
Cdd:COG5805 440 PEERLKKLGE----PFF-TTKEKGtGLGLMVSYKIIENHNGTIDIDSKVGKGTTFT 490
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
271-499 |
1.03e-12 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 70.74 E-value: 1.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 271 ITNISHDLRTPLTSLHGyletLS-LKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQAEREPFSLVDLV 349
Cdd:PRK11091 287 ISTISHELRTPLNGIVG----LSrILLDTELTAEQRKYLKTIHVSAITLGNIFNDIIDMDKMERRKLQLDNQPIDFTDFL 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 350 QDVFQKFELAAQSRGIALQARIPPRVPA-VSADLAMIERVLTNLLDNALRHTpQHGAIEVALTpRDDRVVVT--VSDTGA 426
Cdd:PRK11091 363 ADLENLSGLQAEQKGLRFDLEPLLPLPHkVITDGTRLRQILWNLISNAVKFT-QQGGVTVRVR-YEEGDMLTfeVEDSGI 440
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 976581553 427 GIPLARRAGLF----QRPQRPvsGGTSTNG-GLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIAQPAPGDPQ 499
Cdd:PRK11091 441 GIPEDELDKIFamyyQVKDSH--GGKPATGtGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPAVAEEVEDAF 516
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
266-334 |
1.18e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 63.00 E-value: 1.18e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 976581553 266 QRRELITNISHDLRTPLTSLHGYLETLSlkaDTLADAERRRYLSVALAQSTKVGRLAQALFELARLESG 334
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLR---DEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
381-477 |
3.01e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 62.86 E-value: 3.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 381 DLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQR---PQRPVSGGTSTngGLGLL 457
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERfysLPRPHSGQKST--GLGLA 78
|
90 100
....*....|....*....|
gi 976581553 458 IVHRMLALNGSDIRLVDRDG 477
Cdd:cd16945 79 FVQEVAQLHGGRITLRNRPD 98
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
266-334 |
1.14e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 59.89 E-value: 1.14e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 976581553 266 QRRELITNISHDLRTPLTSLHGYLETLslkADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESG 334
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELL---LDTELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-479 |
1.17e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 61.31 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALRHTpqHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLA 464
Cdd:cd16950 1 LKRVLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRISD 78
|
90
....*....|....*
gi 976581553 465 LNGSDIRLVDRDGRG 479
Cdd:cd16950 79 AHGGSLTLANRAGGG 93
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
264-330 |
3.27e-11 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 58.76 E-value: 3.27e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 976581553 264 DQQRRELITNISHDLRTPLTSLHGYLETlsLKADTLADAERRRYLSVALAQSTKVGRLAQALFELAR 330
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALEL--LEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-486 |
3.69e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 59.78 E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALR--HTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQR--PQRPVSGGTstngGLGLLIVH 460
Cdd:cd16976 1 IQQVLMNLLQNALDamGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPffTTKPVGKGT----GLGLSISY 76
|
90 100
....*....|....*....|....*.
gi 976581553 461 RMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16976 77 GIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-470 |
4.21e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 59.89 E-value: 4.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 387 RVLTNLLDNALRHTP-QHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQR--PQRPVSGGTSTNGGLGLLIVHRML 463
Cdd:cd16953 3 QVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRfyTERPANEAFGQHSGLGLSISRQII 82
|
....*..
gi 976581553 464 ALNGSDI 470
Cdd:cd16953 83 EAHGGIS 89
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-488 |
8.97e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 58.59 E-value: 8.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 383 AMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQrP---QRPVSGGTstngGLGLLIV 459
Cdd:cd16943 2 SQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFD-PfftTKPVGEGT----GLGLSLS 76
|
90 100
....*....|....*....|....*....
gi 976581553 460 HRMLALNGSDIRLVDRDGRGAVFEFALAL 488
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-483 |
3.09e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 58.03 E-value: 3.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 361 QSRGIALQARIPP--RVPAVSADLamIErVLTNLLDNALRHTpqHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQ 438
Cdd:cd16954 15 QRKGVSISLDISPelRFPGERNDL--ME-LLGNLLDNACKWC--LEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQ 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 976581553 439 RPQRpvsGGTSTNG-GLGLLIVHRMLALNGSDIRLVDRDGRGAVFE 483
Cdd:cd16954 90 RGQR---LDEQRPGqGLGLAIAKEIVEQYGGELSLSDSPLGGARFE 132
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-486 |
4.42e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 56.95 E-value: 4.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 388 VLTNLLDNAL--RHTPQHGAIEVALTPRDDRVVVTVSDTGAGIP---LARRAGLFQRPQ-RPVSGGTstngGLGLLIVHR 461
Cdd:cd16921 4 VLTNLLGNAIkfRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDpeyAEKVFGIFQRLHsREEYEGT----GVGLAIVRK 79
|
90 100
....*....|....*....|....*
gi 976581553 462 MLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16921 80 IIERHGGRIWLESEPGEGTTFYFTL 104
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
269-468 |
7.48e-10 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 60.65 E-value: 7.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 269 ELITNISHDLRTPLTSLHGYLETlsLKADTLADAERRRYLSVALAQstkVGRlAQAL----FELARLESGSVqaerEPFS 344
Cdd:COG5806 203 ELAASIAHEVRNPLTVVRGFIQL--LQEPELSDEKRKQYIRIALEE---LDR-AEAIitdyLTFAKPQPEKL----EKID 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 345 LVDLVQDVFQKFELAAQSRGIALQARIPPRVpAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDT 424
Cdd:COG5806 273 VSEELEHVIDVLSPYANMNNVEIQTELEPGL-YIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDKNKVIISIKDT 351
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 976581553 425 GAGIP---LARRAGLFQrpqrpvsgGTSTNG-GLGLLIVHRML-ALNGS 468
Cdd:COG5806 352 GVGMTkeqLERLGEPYF--------STKEKGtGLGTMVSYRIIeAMNGT 392
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-483 |
1.07e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 55.76 E-value: 1.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 388 VLTNLLDNAL----RHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRpqrpvsgGTSTNG----GLGLLIV 459
Cdd:cd16915 4 IVGNLIDNALdalaATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFER-------GVSTKGqgerGIGLALV 76
|
90 100
....*....|....*....|....
gi 976581553 460 HRMLALNGSDIRLVDRDGRGAVFE 483
Cdd:cd16915 77 RQSVERLGGSITVESEPGGGTTFS 100
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
381-480 |
2.32e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 54.85 E-value: 2.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 381 DLAMIERVLTNLLDNA------LRHTPQHGAIEVAlTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTstngGL 454
Cdd:cd16944 1 DTTQISQVLTNILKNAaeaiegRPSDVGEVRIRVE-ADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGT----GL 75
|
90 100
....*....|....*....|....*.
gi 976581553 455 GLLIVHRMLALNGSDIRLVDRDGRGA 480
Cdd:cd16944 76 GLAIVKKIMEEHGGRISLSNREAGGA 101
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-488 |
6.77e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 53.48 E-value: 6.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALRHTPQhgAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG--GLGLLIVHRM 462
Cdd:cd16949 1 LARALENVLRNALRYSPS--KILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGgtGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 976581553 463 LALNGSDIRLVDRDGRGAVFEFALAL 488
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
260-442 |
7.40e-09 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 57.72 E-value: 7.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 260 LTRQDQQR----RELITNISHDLRTPLTSLHGYLETL-SLKADTLADAErrrylSVALAQstkVGRLAQAL---FELARL 331
Cdd:PRK10815 255 LLKNERERytkyRTTLTDLTHSLKTPLAVLQSTLRSLrSGKQMSVEQAE-----PIMLEQ---ISRISQQIgyyLHRASM 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 332 ESGSVQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIErVLTNLLDNALRHTPQHgaIEVALT 411
Cdd:PRK10815 327 RSEHNLLSRELHSVAPLLDNLTSALNKVYQRKGVNITLDISPEITFVGEKNDFME-VMGNVLDNACKYCLEF--VEISAR 403
|
170 180 190
....*....|....*....|....*....|.
gi 976581553 412 PRDDRVVVTVSDTGAGIPLARRAGLFQRPQR 442
Cdd:PRK10815 404 QTDEHLHIVVEDDGPGIPESKRELIFDRGQR 434
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-486 |
3.37e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 51.24 E-value: 3.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDN---ALRH-TPQHGAIEVALTPRDDR-VVVTVSDTGAGIPLARRAGLFQrpqrPVSGGTSTNGGLGLLIV 459
Cdd:cd16920 1 IQQVLINLVRNgieAMSEgGCERRELTIRTSPADDRaVTISVKDTGPGIAEEVAGQLFD----PFYTTKSEGLGMGLSIC 76
|
90 100
....*....|....*....|....*..
gi 976581553 460 HRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16920 77 RSIIEAHGGRLSVESPAGGGATFQFTL 103
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
274-495 |
3.96e-08 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 56.14 E-value: 3.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 274 ISHDLRTPLTSLHGYLETLSLKadTL-ADAERrryLSVALAQSTKVG-RLAQALFELARLESGSVQAEREPFSLVDLVQD 351
Cdd:PRK10841 454 VSHELRTPLYGIIGNLDLLQTK--ELpKGVDR---LVTAMNNSSSLLlKIISDILDFSKIESEQLKIEPREFSPREVINH 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 352 VFQKF-ELAAQSRgIALQARIPPRVP-AVSADLAMIERVLTNLLDNALRHTpQHGAIEVALTPRDDRVVVTVSDTGAGIP 429
Cdd:PRK10841 529 ITANYlPLVVKKR-LGLYCFIEPDVPvALNGDPMRLQQVISNLLSNAIKFT-DTGCIVLHVRVDGDYLSFRVRDTGVGIP 606
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 976581553 430 LARRAGLFQrPQRPVSGGTSTN---GGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIAQPAP 495
Cdd:PRK10841 607 AKEVVRLFD-PFFQVGTGVQRNfqgTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIPLYGAQYPQ 674
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-468 |
4.58e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 51.31 E-value: 4.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 385 IERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG--GLGLLIVHRM 462
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGgsGLGLAICHNI 84
|
....*..
gi 976581553 463 -LALNGS 468
Cdd:cd16946 85 aLAHGGT 91
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
276-482 |
8.01e-08 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 54.84 E-value: 8.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 276 HDLRTPLTSLHGYLETLSlkadTLadaeRRRYLSvalAQSTKVGRLAQALFELAR-LESGSVQAEREpfsLVDLVQDVFQ 354
Cdd:PRK15053 326 STLNAQLTQIKQYVESLR----TL----RHEHLN---WMSTLNGLLQMKEYDRVLeMVQGESQAQQQ---LIDSLREAFA 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 355 KFELAA-------QSRGIALQARIPP-----RVPAvSADLAMIERVLTNLLDNA----LRHTPQHGAIEVALTPRDDRVV 418
Cdd:PRK15053 392 DRQVAGllfgkvqRARELGLKMVIVPgsqlsQLPP-GLDSTEFAAIVGNLLDNAfeasLRSDEGNKIVELFLSDEGDDVV 470
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 976581553 419 VTVSDTGAGIPLARRAGLFqrpQRPVSGGTSTNG--GLGLLIVHRMLALNGSDIRLVDRDGRGAVF 482
Cdd:PRK15053 471 IEVADQGCGVPESLRDKIF---EQGVSTRADEPGehGIGLYLIASYVTRCGGVITLEDNDPCGTLF 533
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
245-489 |
8.86e-08 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 53.08 E-value: 8.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 245 AFAQMADRIGEQWRALTRQDQQRRELI-----TNIS---HDlrtpltSLHGYLETLSLKADTLADAERRRYLSVALAQST 316
Cdd:COG4585 23 ALVLLRARRAERAAELERELAARAEEAreeerRRIArelHD------GVGQSLSAIKLQLEAARRLLDADPEAAREELEE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 317 KVGRLAQALFELARLESGSVQAEREPFSLVDLVQDVFQKFELAAqsrGIALQARIPPRVPAVSADLAM-IERVLTNLLDN 395
Cdd:COG4585 97 IRELAREALAELRRLVRGLRPPALDDLGLAAALEELAERLLRAA---GIRVELDVDGDPDRLPPEVELaLYRIVQEALTN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 396 ALRHTpQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGlfqrpqrpvsggtstnGGLGLL-IVHRMLALNGSdIRLVD 474
Cdd:COG4585 174 ALKHA-GATRVTVTLEVDDGELTLTVRDDGVGFDPEAAPG----------------GGLGLRgMRERAEALGGT-LTIGS 235
|
250
....*....|....*
gi 976581553 475 RDGRGAVFEFALALA 489
Cdd:COG4585 236 APGGGTRVRATLPLA 250
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
226-499 |
3.74e-07 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 52.76 E-value: 3.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 226 PVPRPAPGRRGDDLAVLESAFAQMAD-----RIGEQWRALTRQDQQRRELIT------NISHDLRTPLTSLHGYLEtlsL 294
Cdd:PRK13837 398 GRQRYGLRPPAGELQLLELALDCLAHaierrRLETERDALERRLEHARRLEAvgtlasGIAHNFNNILGAILGYAE---M 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 295 KADTLADAER-RRYLSVALAQSTKVGRLAQALFELARLESGSVQaerePFSLVDLVQDVFQKFElAAQSRGIALQARIPP 373
Cdd:PRK13837 475 ALNKLARHSRaARYIDEIISAGARARLIIDQILAFGRKGERNTK----PFDLSELVTEIAPLLR-VSLPPGVELDFDQDQ 549
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 374 RVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDR---------------VVVTVSDTGAGIPLARRAGLFQ 438
Cdd:PRK13837 550 EPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAKLRapkvlshgvlppgryVLLRVSDTGAGIDEAVLPHIFE 629
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 976581553 439 RPQRPVSGGTstngGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEfaLALAIAQPAPGDPQ 499
Cdd:PRK13837 630 PFFTTRAGGT----GLGLATVHGIVSAHAGYIDVQSTVGRGTRFD--VYLPPSSKVPVAPQ 684
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-482 |
4.03e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 48.15 E-value: 4.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 387 RVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALN 466
Cdd:cd16923 3 RVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIAKAIIELH 82
|
90
....*....|....*.
gi 976581553 467 GSDIRlVDRDGRGAVF 482
Cdd:cd16923 83 GGSAS-AEYDDNHDLF 97
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
388-462 |
7.62e-07 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 47.26 E-value: 7.62e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 976581553 388 VLTNLLDNALRHT---PQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGlfqrPQRPVSGgtstnGGLGLLIVHRM 462
Cdd:cd16936 4 AVSEAVTNAVRHAyrhDGPGPVRLELDLDPDRLRVEVTDSGPGFDPLRPAD----PDAGLRE-----GGRGLALIRAL 72
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
363-462 |
9.03e-07 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 47.99 E-value: 9.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 363 RGIALQARIPPRvpavsaDLAMIERVLTNLLDNALRHTPQH---GAIEVALTPRDDRVVVTVSDTGAGIPLArraglfqR 439
Cdd:COG2172 19 RALLRELGLDED------DADDLVLAVSEAVTNAVRHAYGGdpdGPVEVELELDPDGLEIEVRDEGPGFDPE-------D 85
|
90 100
....*....|....*....|...
gi 976581553 440 PQRPVSggTSTNGGLGLLIVHRM 462
Cdd:COG2172 86 LPDPYS--TLAEGGRGLFLIRRL 106
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
344-483 |
1.54e-06 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 50.68 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 344 SLVDLVQD-VFQKFELAAQSR----GIALQARIPPRVPAvSADLAMIER---VLTNLLDNALRHTPQ--HGAIEVALTPR 413
Cdd:PRK11086 386 SLLGKIKSpVIAGFLLGKISRarelGITLIISEDSQLPD-SGDEDQVHElitILGNLIENALEAVGGeeGGEISVSLHYR 464
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 976581553 414 DDRVVVTVSDTGAGIPLARRAGLFQRpqrpvsgGTSTNG---GLGLLIVHRML-ALNGSdIRLVDRDGRGAVFE 483
Cdd:PRK11086 465 NGWLHCEVSDDGPGIAPDEIDAIFDK-------GYSTKGsnrGVGLYLVKQSVeNLGGS-IAVESEPGVGTQFF 530
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
12-487 |
1.99e-06 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 50.29 E-value: 1.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 12 VFAVLLLACSGASAWLQIRANDMREKEVVQALSRDLAAHIASSTPLMDANGLRPDAVRRLFGQLMGVNPSVEVYLLDNAG 91
Cdd:COG3920 38 LLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAALLALLVLLLLLLLAAAALALALLLAALAGLLLLAALL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 92 RIEGDDAPPGHVKRSRVDLAPVQRFIAGEPLPILGDDPRSVDARKVFSAAPLQRAGQPPSGYVYVVLLGEAHDRLAARVD 171
Cdd:COG3920 118 LLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAALLLLAEELAALRLAAAALLLLLAALLDLGLALAALAAA 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 172 AGNVLRTTLWSMAVVALLGLVAGLIAFSFITRPLRRLTDAMRRFDANGAPDTQPPVPRPAPG--RRGDDLAVLESAFAQM 249
Cdd:COG3920 198 ALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEELERRRRARGLGRLLLLLLLllLLLRALLLLAAGIRLV 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 250 ADRIGEQWRALTRQDQQRRELITNISH----DLRTpLTSLhgyletLSLKADTLADAE--------RRRYLSVALAQStk 317
Cdd:COG3920 278 ITERKRAEEELEASLEEKELLLRELHHrvknNLQV-VSSL------LRLQARRADDPEarealeesQNRIQALALVHE-- 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 318 vgRLAQalfelarlesgsvQAEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPP-RVPAVSA-DLAMIervLTNLLDN 395
Cdd:COG3920 349 --LLYQ-------------SEDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGPDvELPADAAvPLGLI---LNELVTN 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 396 ALRH---TPQHGAIEVALTPRDDRVVVTVSDTGAGIPLArraglFQRPQRpvsggtstnGGLGLLIVHRMLA-LNGSdIR 471
Cdd:COG3920 411 ALKHaflSGEGGRIRVSWRREDGRLRLTVSDNGVGLPED-----VDPPAR---------KGLGLRLIRALVRqLGGT-LE 475
|
490
....*....|....*.
gi 976581553 472 LVDRDGRGAVFEFALA 487
Cdd:COG3920 476 LDRPEGTRVRITFPLA 491
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
389-487 |
3.10e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 46.04 E-value: 3.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 389 LTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNG--GLGLLIVHRMLALN 466
Cdd:cd16952 5 FSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGgtGLGLAIVKHVMSRH 84
|
90 100
....*....|....*....|.
gi 976581553 467 GSDIRLVDRDGRGAVFEFALA 487
Cdd:cd16952 85 DARLLIASELGKGSRFTCLFP 105
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-487 |
1.55e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 43.81 E-value: 1.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 388 VLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIP---LARragLFQRpqrpvsGGTSTNG-------GLGLL 457
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPeedLPR---VFDK------GFTGENGrnfqestGMGLY 79
|
90 100 110
....*....|....*....|....*....|
gi 976581553 458 IVHRMLALNGSDIRLVDRDGRGAVFEFALA 487
Cdd:cd16948 80 LVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
371-486 |
2.83e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 43.66 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 371 IPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGLFQRP-QRPVSGGTS 449
Cdd:cd16947 7 IPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLyTLEDSRNSA 86
|
90 100 110
....*....|....*....|....*....|....*...
gi 976581553 450 TNG-GLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFAL 486
Cdd:cd16947 87 KQGnGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-486 |
3.55e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.16 E-value: 3.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 387 RVLTNLLDNALRHTPQhGAIEVALTPRDDRVVVTVSDTGAGIPLARRAGlfqrpqrpvsggtstNGGLGLLIVH-RMLAL 465
Cdd:cd16917 3 RIVQEALTNALKHAGA-SRVRVTLSYTADELTLTVVDDGVGFDGPAPPG---------------GGGFGLLGMReRAELL 66
|
90 100
....*....|....*....|.
gi 976581553 466 NGSdIRLVDRDGRGAVFEFAL 486
Cdd:cd16917 67 GGT-LTIGSRPGGGTRVTARL 86
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
202-253 |
7.29e-05 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 40.12 E-value: 7.29e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 976581553 202 TRPLRRLTDAMRRFdANGAPDTQPPVprpapgRRGDDLAVLESAFAQMADRI 253
Cdd:cd06225 1 TRPLRRLTEAARRI-AEGDLDVRVPV------RSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
21-491 |
3.96e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 43.18 E-value: 3.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 21 SGASAWLQIRANDMREKEVVQALSRDLAAHIASSTPLMDANGLRPDAVRRLFGQLMGVNPSVEVYLLDNAGRIEGDDAPP 100
Cdd:COG2770 53 LLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 101 GHVKRSRVDLAPVQRFIAGEPLPILGDDPRSVDARKVFSAAPLQRAGQPPSGYVYVVLLGEAHDRLAARVDAGNVLRTTL 180
Cdd:COG2770 133 ALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 181 WSMAVVALLGLVAGLIAFSF---ITRPLRRLTDAMRRFdANGAPDTQPPVprpapgRRGDDLAVLESAFAQMADRIGEQW 257
Cdd:COG2770 213 LLLLLALLALLLALLLALLLarrITRPLRRLAEAARRI-AAGDLDVRIPV------SRKDEIGELARAFNRMADSLRESI 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 258 RALTRQDQQRRELITNISHDLRTPLTSLHGYLETLSLKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQ 337
Cdd:COG2770 286 EEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLAL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 338 AEREPFSLVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRV 417
Cdd:COG2770 366 ELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAI 445
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 976581553 418 VVTVSDTGAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIA 491
Cdd:COG2770 446 AAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLL 519
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-479 |
8.17e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 39.71 E-value: 8.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 377 AVSADLAM-IERVLTNLLDNALRHT---PQHGAIEVALTPRDDRVVVTVSDTGAGIPlarraglfqrpqrpvSGGTSTN- 451
Cdd:cd16951 31 PVSSEVATaIGLVVNELLQNALKHAfsdREGGTITIRSVVDGDYLRITVIDDGVGLP---------------QDEDWPNk 95
|
90 100
....*....|....*....|....*...
gi 976581553 452 GGLGLLIVHRMLALNGSDIRLVDRDGRG 479
Cdd:cd16951 96 GSLGLQIVRSLVEGELKAFLEVQSAENG 123
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
274-432 |
1.80e-03 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 40.81 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 274 ISHDLRTPLTSLHGYLETLSLKADT-LADAER-RRYLSVALAQSTKVGRLAQALFELARLEsgsvQAEREPFSLVDLVQD 351
Cdd:PRK13557 170 IAHDFNNLLQVMSGYLDVIQAALSHpDADRGRmARSVENIRAAAERAATLTQQLLAFARKQ----RLEGRVLNLNGLVSG 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 352 VFqkfELAAQSRG--IALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVA--------------LTPRDD 415
Cdd:PRK13557 246 MG---ELAERTLGdaVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDAMPEGGRVTIRtrnveiededlamyHGLPPG 322
|
170 180
....*....|....*....|.
gi 976581553 416 R-VVVTVSDTGAGIP---LAR 432
Cdd:PRK13557 323 RyVSIAVTDTGSGMPpeiLAR 343
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
395-462 |
2.29e-03 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 38.04 E-value: 2.29e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 976581553 395 NALRH---TPQHGAIEVALTPRDDRVVVTVSDTGAGIPLARRAglfqRPQRPVSGGTSTNGGLGLLIVHRM 462
Cdd:pfam13581 42 NAVEHayrEGPEGPVEVRLTSDGGGLVVTVADSGPPFDPLTLP----PPDLEEPDEDRKEGGRGLALIRGL 108
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
105-492 |
2.33e-03 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 40.25 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 105 RSRVDLAPVQRFIAGEPLPILGDDPRSVDARKVFSAAPLQRAGQPPSGYVYVVLLGEAHDRLAARVDAGNVLRTTLWSMA 184
Cdd:COG3850 46 LSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 185 VVALLGLVAGLIAFSFITRPLRRLTDAMRRFdANGAPDTQPPVprpapgRRGDDLAVLESAFAQMADRIGEQWRALTRQD 264
Cdd:COG3850 126 LALLLALLLAYLLRRRIVRPLRRLTQAAERI-ARGDFDARVPV------SGRDELGTLARAFNRMADELQELYAELEEEE 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 265 QQRRELITNISHDLRTPLTSLHGYLETLSLKADTLADAERRRYLSVALAQSTKVGRLAQALFELARLESGSVQAEREPFS 344
Cdd:COG3850 199 ELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASAL 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 345 LVDLVQDVFQKFELAAQSRGIALQARIPPRVPAVSADLAMIERVLTNLLDNALRHTPQHGAIEVALTPRDDRVVVTVSDT 424
Cdd:COG3850 279 LLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAA 358
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 976581553 425 GAGIPLARRAGLFQRPQRPVSGGTSTNGGLGLLIVHRMLALNGSDIRLVDRDGRGAVFEFALALAIAQ 492
Cdd:COG3850 359 GAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVLIVSIIAG 426
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
201-256 |
2.65e-03 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 36.07 E-value: 2.65e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 976581553 201 ITRPLRRLTDAMRRFdANGAPDTQPPVPRPapgrrgDDLAVLESAFAQMADRIGEQ 256
Cdd:smart00304 3 LLRPLRRLAEAAQRI-ADGDLTVRLPVDGR------DEIGELARAFNEMADRLEET 51
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
386-479 |
4.41e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 36.97 E-value: 4.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 976581553 386 ERVLTNLLDNALRHTPQHGAIE-----------VALTPRD----DRVVVTVSDTGAGIPLARRAGLFQrP---QRPVSGG 447
Cdd:cd16919 2 ELAILNLAVNARDAMPEGGRLTietsnqrvdadYALNYRDlipgNYVCLEVSDTGSGMPAEVLRRAFE-PfftTKEVGKG 80
|
90 100 110
....*....|....*....|....*....|..
gi 976581553 448 TstngGLGLLIVHRMLALNGSDIRLVDRDGRG 479
Cdd:cd16919 81 T----GLGLSMVYGFVKQSGGHLRIYSEPGVG 108
|
|
| HAMP |
pfam00672 |
HAMP domain; |
201-253 |
4.87e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 35.29 E-value: 4.87e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 976581553 201 ITRPLRRLTDAMRRFdANGAPDTQPPVPRPapgrrgDDLAVLESAFAQMADRI 253
Cdd:pfam00672 6 ILRPLRRLAEAARRI-ASGDLDVRLPVSGR------DEIGELARAFNQMAERL 51
|
|
| |
