|
Name |
Accession |
Description |
Interval |
E-value |
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
62-237 |
4.94e-115 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 344.50 E-value: 4.94e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHE 141
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 142 VGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHL 221
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 16566553 222 ISKLNSYYGNVPVIEV 237
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
60-687 |
2.85e-55 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 206.06 E-value: 2.85e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 60 EDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHyqhgGVIC-TQVHKQTVVQLALRVADEMDVNI 138
Cdd:PRK11131 71 ENLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVK----GLIGhTQPRRLAARTVANRIAEELETEL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 139 GHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSS 218
Cdd:PRK11131 147 GGCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 219 ---PHLISKlnsYYGNVPVIEVKNK-HPVEVVY--LSE----AQKDSFESILRLIFEIHHSGeKGDIVVFLACEQDIEKV 288
Cdd:PRK11131 227 tidPERFSR---HFNNAPIIEVSGRtYPVEVRYrpIVEeaddTERDQLQAIFDAVDELGREG-PGDILIFMSGEREIRDT 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 289 CETVyqgSNLNpdLGELVVVPLYPKekcslfkpLDETEKRcQVYQ----RRVVLTTSSGEFLIWSNSVRFVIDVGVERRK 364
Cdd:PRK11131 303 ADAL---NKLN--LRHTEILPLYAR--------LSNSEQN-RVFQshsgRRIVLATNVAETSLTVPGIKYVIDPGTARIS 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 365 VYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEE-FASkdmtplKPA----EMQEANLTSMVLFMKRIdia 439
Cdd:PRK11131 369 RYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDdFLS------RPEftdpEILRTNLASVILQMTAL--- 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 440 GLGHCD---FMNRPAPESLMQALEDLDYLAALDNDGN-----LSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAA 511
Cdd:PRK11131 440 GLGDIAafpFVEAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITS 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 512 MVTA--PNcfsHVPHGAEEAALTCWKTFLHPEGDHFTLISI--YKAYQDTTLNSSSeycVEKWCRDYFLNCSALRMADVI 587
Cdd:PRK11131 520 ALSIqdPR---ERPMDKQQASDEKHRRFADKESDFLAFVNLwnYLQEQQKALSSNQ---FRRLCRTDYLNYLRVREWQDI 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 588 RAELLEIIKRIELPY-AEPAfgskeNTLNIKKALLSGYFMQIA-RDVD-----GSGNylmlthkqvAQLHPLSGYSITKK 660
Cdd:PRK11131 594 YTQLRQVVKELGIPVnSEPA-----EYREIHTALLTGLLSHIGmKDAEkqeytGARN---------ARFSIFPGSGLFKK 659
|
650 660
....*....|....*....|....*..
gi 16566553 661 MPEWVLFHKFSISENNYIRITSEISPE 687
Cdd:PRK11131 660 PPKWVMVAELVETSRLWGRIAARIEPE 686
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
241-404 |
2.97e-53 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 181.58 E-value: 2.97e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 241 HPVEVVYLSEA-----------QKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQgSNLNPDLGELVVVP 309
Cdd:cd18791 1 FPVEVYYLEDIlellgissekeDPDYVDAAVRLILQIHRTEEPGDILVFLPGQEEIERLCELLRE-ELLSPDLGKLLVLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 310 LYPKEKCSLFKPLDEtekRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRK 389
Cdd:cd18791 80 LHSSLPPEEQQRVFE---PPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRA 156
|
170
....*....|....*
gi 16566553 390 QILGSSSSGKFFCLY 404
Cdd:cd18791 157 GRAGRTRPGKCYRLY 171
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
75-654 |
4.22e-52 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 194.53 E-value: 4.22e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 75 LLQNQIVIVSGDAKCGKSAQVPQWCAEyclSIHYQHGGVICTQ--------VhkqtvvqlALRVADEMDVNIGHEVGYVI 146
Cdd:COG1643 23 LRAHQVVVLAAPPGAGKTTQLPLALLE---LGWGAGGRIGMLEprrlaaraA--------AERMAEELGEPVGETVGYRV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 147 PFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATD--------VLLGLlkdvllaRPELKLIINS- 217
Cdd:COG1643 92 RFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADlllallldLQPAL-------RPDLKLLVMSa 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 218 -------SPHLisklnsyyGNVPVIEVKNK-HPVEVVYL--SEAQKDSFESILRLIFEIHHSGEkGDIVVFLACEQDIEK 287
Cdd:COG1643 165 tldaerfARLL--------GDAPVIESSGRtYPVEVRYRplPADERDLEDAVADAVREALAEEP-GDILVFLPGEREIRR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 288 VCETvyqgsnLNPDLG-ELVVVPLY----PKEKCSLFKPLDETekrcqvyQRRVVLTTS----S----GefliwsnsVRF 354
Cdd:COG1643 236 TAEA------LRGRLPpDTEILPLYgrlsAAEQDRAFAPAPHG-------RRRIVLATNiaetSltvpG--------IRY 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 355 VIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEE-FASkdMTPLKPAEMQEANLTSMVLFM 433
Cdd:COG1643 295 VIDSGLARIPRYDPRSGVTRLPTERISQASANQRAGRAGRLAPGICYRLWSEEdFAR--RPAFTDPEILRADLASLILEL 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 434 KRI---DIAGLghcDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIA 510
Cdd:COG1643 373 AAWglgDPEDL---PFLDPPPARAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILA 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 511 AMVTAPNCFSHVPHGAEEAALTCWKTFLHPegdhftlisiykayqdttlnssseycvekwcRDYFLNCSALRmadviraE 590
Cdd:COG1643 450 ALLSERDPRRGAAGSDLLARLNLWRRLREQ-------------------------------QREFLSYLRLR-------E 491
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16566553 591 LLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLmLTHKQVAQLHPLSG 654
Cdd:COG1643 492 WRDLARQLRRLLGEGANEEPADYEAIGLLLALAYPDRIARRRGEGGRYL-LARGRGAALFPGSP 554
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
458-547 |
4.07e-25 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 100.00 E-value: 4.07e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 458 ALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCF---SHVPHGAEEAALTCW 534
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFvqpNFLDPRSAAKAARRR 80
|
90 100
....*....|....*....|....
gi 16566553 535 KTFLHPE-----------GDHFTL 547
Cdd:pfam04408 81 RRAADEKarakfarldleGDHLTL 104
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
464-548 |
1.26e-22 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 92.33 E-value: 1.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 464 YLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFshvPHGAEEAALTCWKTFLHPEGD 543
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPR---PKEKREDADAARRRFADPESD 77
|
....*
gi 16566553 544 HFTLI 548
Cdd:smart00847 78 HLTLL 82
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
78-191 |
2.64e-03 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 39.78 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 78 NQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVH--KQTVVQLALRVADEMDVNIGHEVGYVIP-----FEN 150
Cdd:smart00487 24 LRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTRElaEQWAEELKKLGPSLGLKVVGLYGGDSKReqlrkLES 103
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 16566553 151 CCTNetILrYCTDDMLQREMMSNPF-LGSYGVIILDDIHERS 191
Cdd:smart00487 104 GKTD--IL-VTTPGRLLDLLENDKLsLSNVDLVILDEAHRLL 142
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
62-237 |
4.94e-115 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 344.50 E-value: 4.94e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHE 141
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 142 VGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHL 221
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 16566553 222 ISKLNSYYGNVPVIEV 237
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
62-237 |
1.92e-67 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 220.15 E-value: 1.92e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQ-IVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSgIVLVSGEPGSGKSTQVPQWCAEFALSRGFQKGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPH 220
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPA 160
|
170
....*....|....*..
gi 16566553 221 LISKLNSYYGNVPVIEV 237
Cdd:cd17986 161 LEPKLRAFWGNPPVVHV 177
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
78-237 |
4.20e-58 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 194.22 E-value: 4.20e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 78 NQIVIVSGDAKCGKSAQVPQWCAEYCLSIHyQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETI 157
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAKG-GKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 158 LRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17917 80 IKFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIHI 159
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
51-237 |
1.11e-57 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 194.17 E-value: 1.11e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 51 RYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSiHYQHGGVICTQVHKQTVVQLALRV 130
Cdd:cd17973 2 RYFEILEKRRELPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELP-HQPKKLVACTQPRRVAAMSVAQRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 131 ADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPE 210
Cdd:cd17973 81 AEEMDVKLGEEVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPD 160
|
170 180
....*....|....*....|....*..
gi 16566553 211 LKLIINSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17973 161 LKLIVMSATLDAGKFQKYFDNAPLLKV 187
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
60-687 |
2.85e-55 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 206.06 E-value: 2.85e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 60 EDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHyqhgGVIC-TQVHKQTVVQLALRVADEMDVNI 138
Cdd:PRK11131 71 ENLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVK----GLIGhTQPRRLAARTVANRIAEELETEL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 139 GHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSS 218
Cdd:PRK11131 147 GGCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 219 ---PHLISKlnsYYGNVPVIEVKNK-HPVEVVY--LSE----AQKDSFESILRLIFEIHHSGeKGDIVVFLACEQDIEKV 288
Cdd:PRK11131 227 tidPERFSR---HFNNAPIIEVSGRtYPVEVRYrpIVEeaddTERDQLQAIFDAVDELGREG-PGDILIFMSGEREIRDT 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 289 CETVyqgSNLNpdLGELVVVPLYPKekcslfkpLDETEKRcQVYQ----RRVVLTTSSGEFLIWSNSVRFVIDVGVERRK 364
Cdd:PRK11131 303 ADAL---NKLN--LRHTEILPLYAR--------LSNSEQN-RVFQshsgRRIVLATNVAETSLTVPGIKYVIDPGTARIS 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 365 VYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEE-FASkdmtplKPA----EMQEANLTSMVLFMKRIdia 439
Cdd:PRK11131 369 RYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDdFLS------RPEftdpEILRTNLASVILQMTAL--- 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 440 GLGHCD---FMNRPAPESLMQALEDLDYLAALDNDGN-----LSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAA 511
Cdd:PRK11131 440 GLGDIAafpFVEAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITS 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 512 MVTA--PNcfsHVPHGAEEAALTCWKTFLHPEGDHFTLISI--YKAYQDTTLNSSSeycVEKWCRDYFLNCSALRMADVI 587
Cdd:PRK11131 520 ALSIqdPR---ERPMDKQQASDEKHRRFADKESDFLAFVNLwnYLQEQQKALSSNQ---FRRLCRTDYLNYLRVREWQDI 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 588 RAELLEIIKRIELPY-AEPAfgskeNTLNIKKALLSGYFMQIA-RDVD-----GSGNylmlthkqvAQLHPLSGYSITKK 660
Cdd:PRK11131 594 YTQLRQVVKELGIPVnSEPA-----EYREIHTALLTGLLSHIGmKDAEkqeytGARN---------ARFSIFPGSGLFKK 659
|
650 660
....*....|....*....|....*..
gi 16566553 661 MPEWVLFHKFSISENNYIRITSEISPE 687
Cdd:PRK11131 660 PPKWVMVAELVETSRLWGRIAARIEPE 686
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
241-404 |
2.97e-53 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 181.58 E-value: 2.97e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 241 HPVEVVYLSEA-----------QKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQgSNLNPDLGELVVVP 309
Cdd:cd18791 1 FPVEVYYLEDIlellgissekeDPDYVDAAVRLILQIHRTEEPGDILVFLPGQEEIERLCELLRE-ELLSPDLGKLLVLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 310 LYPKEKCSLFKPLDEtekRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRK 389
Cdd:cd18791 80 LHSSLPPEEQQRVFE---PPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRA 156
|
170
....*....|....*
gi 16566553 390 QILGSSSSGKFFCLY 404
Cdd:cd18791 157 GRAGRTRPGKCYRLY 171
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
75-654 |
4.22e-52 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 194.53 E-value: 4.22e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 75 LLQNQIVIVSGDAKCGKSAQVPQWCAEyclSIHYQHGGVICTQ--------VhkqtvvqlALRVADEMDVNIGHEVGYVI 146
Cdd:COG1643 23 LRAHQVVVLAAPPGAGKTTQLPLALLE---LGWGAGGRIGMLEprrlaaraA--------AERMAEELGEPVGETVGYRV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 147 PFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATD--------VLLGLlkdvllaRPELKLIINS- 217
Cdd:COG1643 92 RFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADlllallldLQPAL-------RPDLKLLVMSa 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 218 -------SPHLisklnsyyGNVPVIEVKNK-HPVEVVYL--SEAQKDSFESILRLIFEIHHSGEkGDIVVFLACEQDIEK 287
Cdd:COG1643 165 tldaerfARLL--------GDAPVIESSGRtYPVEVRYRplPADERDLEDAVADAVREALAEEP-GDILVFLPGEREIRR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 288 VCETvyqgsnLNPDLG-ELVVVPLY----PKEKCSLFKPLDETekrcqvyQRRVVLTTS----S----GefliwsnsVRF 354
Cdd:COG1643 236 TAEA------LRGRLPpDTEILPLYgrlsAAEQDRAFAPAPHG-------RRRIVLATNiaetSltvpG--------IRY 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 355 VIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEE-FASkdMTPLKPAEMQEANLTSMVLFM 433
Cdd:COG1643 295 VIDSGLARIPRYDPRSGVTRLPTERISQASANQRAGRAGRLAPGICYRLWSEEdFAR--RPAFTDPEILRADLASLILEL 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 434 KRI---DIAGLghcDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIA 510
Cdd:COG1643 373 AAWglgDPEDL---PFLDPPPARAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILA 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 511 AMVTAPNCFSHVPHGAEEAALTCWKTFLHPegdhftlisiykayqdttlnssseycvekwcRDYFLNCSALRmadviraE 590
Cdd:COG1643 450 ALLSERDPRRGAAGSDLLARLNLWRRLREQ-------------------------------QREFLSYLRLR-------E 491
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16566553 591 LLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLmLTHKQVAQLHPLSG 654
Cdd:COG1643 492 WRDLARQLRRLLGEGANEEPADYEAIGLLLALAYPDRIARRRGEGGRYL-LARGRGAALFPGSP 554
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
58-237 |
1.09e-42 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 152.64 E-value: 1.09e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 58 EREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSihyQHGGVICTQVHKQTVVQLALRVADEMDVN 137
Cdd:cd17971 2 QRESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYT---SRGKIGCTQPRRVAAMSVAKRVAEEFGCC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 138 IGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINS 217
Cdd:cd17971 79 LGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTS 158
|
170 180
....*....|....*....|
gi 16566553 218 SPHLISKLNSYYGNVPVIEV 237
Cdd:cd17971 159 ATLDAVKFSQYFYEAPIFTI 178
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
62-237 |
2.01e-40 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 146.11 E-value: 2.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAE--YClsihyQHGGVI-CTQVHKQTVVQLALRVADEMDVNI 138
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEagYT-----KGGGKIgCTQPRRVAAMSVAARVAEEMGVKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 139 GHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSS 218
Cdd:cd17974 76 GNEVGYSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSA 155
|
170
....*....|....*....
gi 16566553 219 PHLISKLNSYYGNVPVIEV 237
Cdd:cd17974 156 TMDAEKFSAFFDDAPIFRI 174
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
62-235 |
7.76e-38 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 139.03 E-value: 7.76e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQwcaeYCLSIHYQHGGVI-CTQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQ----YLYEAGFARGGMIgITQPRRVAAVSVAKRVAEEMGVELGQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLAR-----PELKLII 215
Cdd:cd17978 77 LVGYSVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRkeqklSPLKVII 156
|
170 180
....*....|....*....|
gi 16566553 216 NSSPHLISKLNSYYGNVPVI 235
Cdd:cd17978 157 MSATLDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
62-218 |
1.86e-37 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 138.37 E-value: 1.86e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEyclsIHYQHGG--VICTQVHKQTVVQLALRVADEMDVNIG 139
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAE----AGWTAGGrvVGCTQPRRVAAVTVAGRVAEEMGAVLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 140 HEVGYVIPFENCCTN-ETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSS 218
Cdd:cd17980 77 HEVGYCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASA 156
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
62-237 |
1.01e-36 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 135.67 E-value: 1.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQwcaeYCLSIHYQHGGVI-CTQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQ----YLHEDGYTDYGMIgCTQPRRVAAMSVAKRVSEEMGVELGE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPH 220
Cdd:cd17983 77 EVGYAIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATM 156
|
170
....*....|....*..
gi 16566553 221 LISKLNSYYGNVPVIEV 237
Cdd:cd17983 157 DADKFADFFGNVPIFTI 173
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
62-237 |
1.29e-33 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 127.28 E-value: 1.29e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSihyQHGGVICTQVHKQTVVQLALRVADEMDVNIGHE 141
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRRVAAISVAQRVAEEMKCTLGSK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 142 VGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDV-----LLGLLKDVLLARPELKLIIN 216
Cdd:cd17984 78 VGYQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDIlfgllKKLFQEKSPNRKEHLKVVVM 157
|
170 180
....*....|....*....|.
gi 16566553 217 SSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17984 158 SATLELAKLSAFFGNCPVFDI 178
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
62-237 |
5.08e-33 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 125.25 E-value: 5.08e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQwcaeYCLSIHYQHggVICTQVHKQTVVQLALRVADEMDVNIGHE 141
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQ----YLLAAGFRH--IACTQPRRIACISLAKRVAFESLNQYGSK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 142 VGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHL 221
Cdd:cd17979 75 VAYQIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATIN 154
|
170
....*....|....*.
gi 16566553 222 ISKLNSYYGNVPVIEV 237
Cdd:cd17979 155 IELFSGYFEGAPVVQV 170
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
62-237 |
3.14e-28 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 111.86 E-value: 3.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCL-SIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNSLqGPPLPVANIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPH 220
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....*..
gi 16566553 221 LISKLNSYYGNVPVIEV 237
Cdd:cd17985 161 NAELFSDYFNSCPVIHI 177
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
62-217 |
2.26e-27 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 109.75 E-value: 2.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQ--WCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVnIG 139
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQflYEAGFGSPESDNPGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 140 HEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVL-----------LGLLKDVLLAR 208
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILigmlsrivplrAKLYLQDQTVK 159
|
....*....
gi 16566553 209 PeLKLIINS 217
Cdd:cd17982 160 P-LKLVIMS 167
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
62-237 |
2.85e-27 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 108.70 E-value: 2.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHyqhgGVIC-TQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIR----GLIGhTQPRRLAARSVAERIAEELKTELGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPH 220
Cdd:cd17989 77 AVGYKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATI 156
|
170
....*....|....*..
gi 16566553 221 LISKLNSYYGNVPVIEV 237
Cdd:cd17989 157 DAERFSRHFNNAPIIEV 173
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
62-237 |
9.69e-26 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 104.49 E-value: 9.69e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAE-YCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGH 140
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEdYVLRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 141 EVGYVIPFENCCTNET-ILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSP 219
Cdd:cd17976 81 NVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*...
gi 16566553 220 HLISKLNSYYGNVPVIEV 237
Cdd:cd17976 161 GDNQRLSRYFGGCPVVRV 178
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
458-547 |
4.07e-25 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 100.00 E-value: 4.07e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 458 ALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCF---SHVPHGAEEAALTCW 534
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFvqpNFLDPRSAAKAARRR 80
|
90 100
....*....|....*....|....
gi 16566553 535 KTFLHPE-----------GDHFTL 547
Cdd:pfam04408 81 RRAADEKarakfarldleGDHLTL 104
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
62-237 |
2.04e-24 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 100.67 E-value: 2.04e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYClsihYQHGG---VICTQVHKQTVVQLALRVADEMDVNI 138
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDC----YANGIpcrIFCTQPRRLAAIAVAERVAAERGEKI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 139 GHEVGYVIPFENCCTNETILRYCTDDMLQREMMS-NPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINS 217
Cdd:cd17987 77 GQTVGYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSS 156
|
170 180
....*....|....*....|
gi 16566553 218 SPHLISKLNSYYGNVPVIEV 237
Cdd:cd17987 157 AALDVNLFIRYFGSCPVIYI 176
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
62-237 |
2.60e-24 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 100.69 E-value: 2.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQwcaeYCLSIHYQHGG-----VICTQVHKQTVVQLALRVADEM-- 134
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQ----FILDDAIERGKgsscrIVCTQPRRISAISVAERVAAERae 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 135 DVNIGHEVGYVIPFEN-CCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKL 213
Cdd:cd17981 77 SCGLGNSTGYQIRLESrKPRKQGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKV 156
|
170 180
....*....|....*....|....
gi 16566553 214 IINSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17981 157 ILMSATLNAEKFSDYFNNCPMIHI 180
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
127-515 |
3.72e-24 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 108.47 E-value: 3.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 127 ALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLL 206
Cdd:PRK11664 65 AQRLAEQLGEKPGETVGYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQ 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 207 A-RPELKLIINSSPHLISKLNSYYGNVPVIEVKNK-HPVEVVYLSEAQKDSFE-----SILRLIFEihhsgEKGDIVVFL 279
Cdd:PRK11664 145 GlRDDLKLLIMSATLDNDRLQQLLPDAPVIVSEGRsFPVERRYQPLPAHQRFDeavarATAELLRQ-----ESGSLLLFL 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 280 ACEQDIEKVCEtvyqgsNLNPDLGELVVV-PLYPkekcSLfkPLDETEKRCQ---VYQRRVVLTTSSGEFLIWSNSVRFV 355
Cdd:PRK11664 220 PGVGEIQRVQE------QLASRVASDVLLcPLYG----AL--SLAEQQKAILpapAGRRKVVLATNIAETSLTIEGIRLV 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 356 IDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKdmTPLKP-AEMQEANLTSMVLfmk 434
Cdd:PRK11664 288 VDSGLERVARFDPKTGLTRLVTQRISQASMTQRAGRAGRLEPGICLHLYSKEQAER--AAAQSePEILHSDLSGLLL--- 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 435 riDIAGLGHCD-----FMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDcvDEVLTI 509
Cdd:PRK11664 363 --ELLQWGCHDpaqlsWLDQPPAAALAAAKRLLQQLGALDGQGRLTARGRKMAALGNDPRLAAMLVAAKEDD--EAALAT 438
|
....*.
gi 16566553 510 AAMVTA 515
Cdd:PRK11664 439 AAKLAA 444
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
24-237 |
6.75e-24 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 101.06 E-value: 6.75e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 24 SSDGDEEEVLAC--EDLELNPFDGLPY----SSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQ 97
Cdd:cd17972 15 SSNIDEGPLAFAtpEQISMDLKNELMYqreqDHNLQQILQERELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 98 WCA-EYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNE--TILrYCTDDMLQREMMSnp 174
Cdd:cd17972 95 YILdDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEVGKSCGYSVRFESVLPRPhaSIL-FCTVGVLLRKLEA-- 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16566553 175 flGSYGV--IILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17972 172 --GIRGIshVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILMSATIDTSMFCEYFFNCPVIEV 234
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
62-237 |
1.17e-23 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 98.83 E-value: 1.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHG--GVICTQVHKQTVVQLALRVADEMDVNIG 139
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEDLLLNGGTAQkcNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 140 -----HEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLI 214
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|...
gi 16566553 215 INSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILRI 183
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
464-548 |
1.26e-22 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 92.33 E-value: 1.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 464 YLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFshvPHGAEEAALTCWKTFLHPEGD 543
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPR---PKEKREDADAARRRFADPESD 77
|
....*
gi 16566553 544 HFTLI 548
Cdd:smart00847 78 HLTLL 82
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
616-696 |
2.42e-20 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 85.77 E-value: 2.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 616 IKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGY-SITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVP 694
Cdd:pfam07717 1 LRAALAAGLYPNVARRDPKGKGYTTLSDNQRVFIHPSSVLfNEKTFPPEWVVYQELVETTKVYIRTVTAISPEWLLLFAP 80
|
..
gi 16566553 695 QY 696
Cdd:pfam07717 81 HI 82
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
62-191 |
3.20e-16 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 77.16 E-value: 3.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 62 LPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQwcaeYCLSIHYQHG---GVICTQVHKQTVVQLALRVADEMDVNI 138
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQ----FILDHYYKRGkycNIVVTQPRRIAAISIARRVSQEREWTL 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 16566553 139 GHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERS 191
Cdd:cd17988 77 GSLVGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERD 129
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
90-237 |
1.82e-13 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 68.90 E-value: 1.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 90 GKSAQVP----QWCAEyclsihyQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDM 165
Cdd:cd17990 29 GKTTRVPlallAELWI-------AGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGYRVRGESRVGRRTRVEVVTEGV 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16566553 166 LQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLA-RPELKLIINSSPHLISKLNSYYGNVPVIEV 237
Cdd:cd17990 102 LLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQLlRDDLRLLAMSATLDGDGLAALLPEAPVVES 174
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
78-191 |
2.64e-03 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 39.78 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16566553 78 NQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVH--KQTVVQLALRVADEMDVNIGHEVGYVIP-----FEN 150
Cdd:smart00487 24 LRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTRElaEQWAEELKKLGPSLGLKVVGLYGGDSKReqlrkLES 103
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 16566553 151 CCTNetILrYCTDDMLQREMMSNPF-LGSYGVIILDDIHERS 191
Cdd:smart00487 104 GKTD--IL-VTTPGRLLDLLENDKLsLSNVDLVILDEAHRLL 142
|
|
| |
