1S4V_A 2 VPASVDWRKKG---AVTS--VKDQG---QCGSCWAFSTIVAVEGINQIKTNk-----LVSLSEQELVDCDTd--QNq--- 63 castor bean Q9XZI2 67 LPIAFDWRNKDg--VNYAgvDRNQHiprYCGSCWAFGSTSALADRFNIKRKna--wpQVYLSVQEVIDCGGq--GS---- 136 dog roundworm P91771 66 LPVAWDWRNINg--VNYAsvDRNQHipqYCGSCWAFGSTSALADRFNIKRKga--wpPAYLSVQEVIDCANa--GS---- 135 Onchocerca vo... O28333 594 LPSRFDWRDYTg--LSa---VRDQGs---CGSCWAHSAVAALESALIVESGas---sSIDLSEQHLLSCEQd--CEvgig 660 Archaeoglobus... XP_002951961 211 LYPVWDSRSVNg--SNYIspVKDQG---GCGSCVAFAVTGAAEAAVAAARKtt--vnSNDYSEQWLFFCNGmssa----- 278 Volvox carter... 2123443A 218 LPLEFDWTSPPdgsRSPVtpIRNQGi---CGSCYASPSAAALEARIRLVSNfs---eQPILSPQTVVDCSPy--SEg--- 286 Schistosoma m... AAC32040 222 LPKEFDWVNRPeglRSPVtpVRNQKt---CGSCYAFASTAAIEARIRLASRfr---lQPILSPQDIIDCSPy--SEg--- 290 Schistosoma j... NP_496805 223 TEPTVDWRP-------FLkpILDQS---TCGGCWAFSMISMIESFFAIQgy-----nTSSLSVQQLLTCDTkvdSTygl- 286 nematode NP_506318 221 LPTGWDWRNVSg--VNYCspTRNQHipvYCGSCWVFGTTGALNDRFNVARKgrwpmtQLSPQEIIDCNGKg--------- 289 nematode 2118248A 231 LPTSWDWRNVHg--INFVspVRNQAs---CGSCYSFASMGMLEARIRILTNns-----qTPILSPQEVVSCsqy------ 294 human
1S4V_A 64 --------GCN-GGLMDYAF-EFIKQR-GG--ITteANYPYEAydgtcdvskenapavsidgh-------------envp 117 castor bean Q9XZI2 137 ---------CE-GGEPGGVY-QFAHEKgIP--He--TCNNYQArdgkctaynkcgscwpddcfsinnytlykvgdfgrvs 201 dog roundworm P91771 136 ---------CE-GGEPGPVY-KYAHEFgIP--He--TCNNYQArdgtcssynkcgscwpgscfsiknytiyrvknygavs 200 Onchocerca vo... O28333 661 dwcwassgDCD-GGWPHKAL-NFIINNgVP--De--SCFPYTAtngncgskcgdwedrtegavyr----------gkvss 724 Archaeoglobus... XP_002951961 279 -----afpNCDsGWFATAAAkVVVTKN-IP--YEl-NY-PYTGsrgcalgspperr------------------------ 324 Volvox carter... 2123443A 287 ---------CN-GGFPFLIAgKYGEDf-gL--PQk-IVIPYTGedtgkctvsknctryyttdysyig------gyygatn 346 Schistosoma m... AAC32040 291 ---------CD-GGFPYLVAgKHGED---FgfVEe-KCNPYTGvksgtcnkllgctryyttdyhyig------gyygatn 350 Schistosoma j... NP_496805 287 -----anvGCK-GGYFQIAG-SYLEVSaAR--Da--SLIPFDLedtscdssffppvvptillfddgyis--gnftaaqli 353 nematode NP_506318 290 --------nCQ-GGEIGNVL-EHAKIQgLV--Ee--GCNVYRAtngecnpyhrcgscwpnecfsltnytryyvkdygqvq 355 nematode 2118248A 295 ------aqgCE-GGFPYLIAgKYAQDFgLV--Ee--ACFPYTGtdspckmkedcfryysseyhyvg--------gfyggc 355 human
1S4V_A 118 endenallkavanqpvSVAIDAggSD-----FQFYSEG----VFTG--SCGTE---------LDHGVAIVGYGTti---- 173 castor bean Q9XZI2 202 gidkmkaeifhngpiaCGIAAT--KA-----FEMYSGG----IYTEe-TS-EE---------IDHIIAVYGWGVdhd--- 256 dog roundworm P91771 201 glhkmkaeiyhhgpiaCGIAAT--KA-----FETYAGG----IYNEr-TN-ED---------IDHIISVHGWGVdse--- 255 Onchocerca vo... O28333 725 nvealkralichgplsVASENW--EHa----LLLVG-------YDDl-ST----------------ICTQKYGKs----- 769 Archaeoglobus... XP_002951961 325 ----aeggfkdtaytdITQAKQ--HIrmygaVTSYFAvygdfFRWRasSPPYAwd--------gISALAG-YHQvlvvgy 389 Volvox carter... 2123443A 347 eklmqlelisngpfpvG-FEVY--ED-----FQFYKEG----IYHHt-TVQTDhynfnpfelTNHAVLLVGYGVdk---- 409 Schistosoma m... AAC32040 351 edlmklelvkngpfpvG-FEVY--GD-----FLQYKSG----VYSHt-DIINNhhpfnpfelTNHAVLLVGYGIdn---- 413 Schistosoma j... NP_496805 354 tmeqniedkvrkgpiaVGMAAG--PD-----IYKYSEG----VYDG--DCGTI---------INHAVVIVGFT------- 404 nematode NP_506318 356 grdkimseikkggpiaCAIGAT--KKf----EYEYVKG----VYSEk-SD-LE---------SNHIISLTGWGVde---- 410 nematode 2118248A 356 nealmklelvhhgpmaVAFEVY--DD-----FLHYKKG----IYHHt-GLRDPfnp---felTNHAVLLVGYGTdsa--- 417 human
1S4V_A 174 dGTK-YWTVKNSWGPE-------WGEKGYIRMERGisdKEGLCGI-AMEASYP 217 castor bean Q9XZI2 257 ssVP-YWIGRNSWGTP-------WGESGWFRVVTS---EYKH-AGsRynlkie 297 dog roundworm P91771 256 sgVP-YWIGRNSWGTP-------WGENGWFRIVTS---EYKN-SSsKYNLKIE 296 Onchocerca volvulus O28333 770 ----gCWILKNSWGVFsgfshdvWHEYGYAYIPYS---GFKYSDIkNGAYYVI 815 Archaeoglobus fulgidus XP_002951961 390 nDIGsYWIVKNSWGTR-------WGDNGFIRISYS---A-NVGFMsGYVGSIi 431 Volvox carteri f. nagariensis 2123443A 410 lSGEpYWKVKNSWGVE-------WGEQGYFRILRG---T-DECGVeSLGVRFD 451 Schistosoma mansoni AAC32040 414 sSNLpYWKIKNSWGQY-------WGEEGYFRILRG---S-DECGVqSIAIKFD 455 Schistosoma japonicum NP_496805 405 --DD-YWIIRNSWGAS-------WGEAGYFRVKRT---PGKDPCQfYKYWSQA 444 nematode NP_506318 411 ngVE-YWIARNSWGEA-------WGELGWFRVVTS---KFKDGQGdQYNMGIE 452 nematode 2118248A 418 sgMD-YWIVKNSWGTG-------WGENGYFRIRRG---TD-ECAIeSIAVAAT 458 human
Jiyao W et al.(2023). "The conserved domain database in 2023.",